Results 161 to 170 of about 5,782,005 (384)

A VH4-34+ myeloma protein with weak autoreactivity

open access: yesHaematologica, 2007
It has been suggested that VH4-34 gene segment expression is counter-selected in multiple myeloma (MM) due to a self-tolerance mechanism. We cloned and sequenced a VH4-34 gene segment from bone marrow mononuclear cells of a stage III MM patient. We show that VH4-34 was expressed by the serum IgA myeloma (M)-protein, as demonstrated by reactivity with ...
Keith M. Thompson   +5 more
openaire   +4 more sources

Enhancement of immunogenicity of a BALB-c myeloma protein in BALB-c mice.

open access: yesJournal of Immunology, 1974
Antiidiotypic antibodies to the BALB/c myeloma protein, LPC-1 (IgG2a(κ)) were induced in BALB/c mice by immunization with protein LPC-1 copolymerized with glutaraldehyde to either rabbit IgG or, preferably, C57BL IgG.
P. J. Peaker, L. Cicurei, A. Nisonoff
semanticscholar   +1 more source

Phenotypical and Genotypical Expansion of Autosomal‐Dominant KDM1A‐Related Neurodevelopmental Disorder Spectrum: A Case Report

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT KDM1A‐related neurodevelopmental disorder (CPRF, OMIM #616728) is characterized by cleft palate, global developmental delay, and distinct facial gestalt, but phenotypic knowledge of this ultra‐rare autosomal dominant disorder is limited. Here, we report on a 13‐year‐old boy with a novel heterozygous, likely pathogenic germline missense variant
Sebastian Burkart   +6 more
wiley   +1 more source

Hypoxia-inducible factor-2 is a novel regulator of aberrant CXCL12 expression in multiple myeloma plasma cells

open access: yesHaematologica, 2010
Background Multiple myeloma is an incurable malignancy of bone marrow plasma cells. Progression of multiple myeloma is accompanied by an increase in bone marrow angiogenesis.
Sally K. Martin   +8 more
doaj   +1 more source

Identification Epitope on VP4 Protein of Senecavirus A Recognized by a Monoclonal Antibody

open access: yesAnimal Research and One Health, EarlyView.
This study aims to identify conserved antigenic epitopes on the SVA VP4 protein using monoclonal antibodies, providing valuable tools for further exploring its functions and developing detection methods. SVA VP4 protein was expressed in Escherichia coli and purified with High‐Affinity Ni‐Charged Resin FF.
Liang Meng   +7 more
wiley   +1 more source

The predictive value of serum myeloma protein in solitary plasmacytoma. [PDF]

open access: yesRadiat Oncol J, 2020
Chang WI   +5 more
europepmc   +1 more source

Structural Studies on the Combining Site of the Myeloma Protein MOPC 315

open access: yes, 1975
1 Analysis of the electron spin resonance spectra of different spin-labelled haptens when bound to the Fv fragment from the immunoglobulin A of the mouse myeloma protein MOPC 315 suggests that the combining site is a cleft of overall dimension 11 A× 9 A×
R. Dwek   +6 more
semanticscholar   +1 more source

Modeling the Effects of Multiple Myeloma on Kidney Function

open access: yes, 2018
Multiple myeloma (MM), a plasma cell cancer, is associated with many health challenges, including damage to the kidney by tubulointerstitial fibrosis.
Ayati, Bruce P.   +2 more
core  

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