aCD47‐C‐miR34a, an antibody‐oligonucleotide platform combining an anti‐CD47 antibody with miR‐34a, is designed for targeted therapy in TNBC. This approach improved delivery and restored the tumor‐suppressing function of miR‐34a, enhanced CD8+ T‐cell activation, and inhibited tumor growth, providing a potential strategy to overcome immune evasion and ...
Youngri Ryu+11 more
wiley +1 more source
Isolated relapse of multiple myeloma in the central nervous system post autologous hematopoietic stem cell transplantation: a case report and literature review. [PDF]
Zhou Y+5 more
europepmc +1 more source
Idiotypic protein‐pulsed dendritic cell vaccination in multiple myeloma [PDF]
Seah H. Lim, R Bailey-Wood
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Radiolabeled Nanogels: From Multimodality Imaging to Combination Therapy of Cancer
Nanogel refers to nanosized particles formed by physical or chemical crosslinking of polymers. Rational design and refinement of nanogel properties are imperative to unlock their full potential, ensuring tailored solutions for personalized cancer management. This review elucidates the transformative potential of radiolabeled nanogels in revolutionizing
Sanchita Ghosh+2 more
wiley +1 more source
Population Pharmacokinetic and Pharmacokinetic-Pharmacodynamic Modeling of Serum M-Protein Response for Modakafusp Alfa in a Phase 1/2 Study of Patients With Relapsed or Refractory Multiple Myeloma. [PDF]
Li C+8 more
europepmc +1 more source
Cytotoxic activity of an interleukin 6-Pseudomonas exotoxin fusion protein on human myeloma cells.
Clay B. Siegall+3 more
openalex +1 more source
PROTEINS IN MULTIPLE MYELOMA [PDF]
Aiko Miyake+2 more
openaire +2 more sources
The regulatory effects and applications of TIGIT/CD155 on the tumor microenvironment in HCC
Background The interaction between TIGIT and CD155 compromises immune cell efficacy in tumor targeting, potentially driving hepatocellular carcinoma (HCC) progression through diverse molecular pathways. What Was Done This study investigates the interplay between CD155 and TIGIT in regulating CD8+ T cell function and elucidates its implications in HCC ...
Wenting Li+10 more
wiley +1 more source
Observation or treatment for smoldering multiple myeloma? A systematic review and meta-analysis of randomized controlled studies. [PDF]
Ntanasis-Stathopoulos I+6 more
europepmc +1 more source
Binding of Rabbit Antibodies to a Mouse Myeloma Protein by the Myeloma Cells in Vitro
openaire +3 more sources