CRISPR/Cas9‐edited tumor‐associated immune cells in cancer immunotherapy
Abstract Immuno‐oncology represents an emerging field that has significantly transformed tumor therapeutics, with immune cells serving as the cellular foundations of cancer immunotherapy. Due to its high efficiency and sensitivity, CRISPR/Cas9 genome editing is a highly promising technique for precise and rapid gene modification.
Yuhui Ma+6 more
wiley +1 more source
Current Anti-Myeloma Chimeric Antigen Receptor-T Cells: Novel Targets and Methods. [PDF]
Vural E, Beksaç M.
europepmc +1 more source
Long‐term survival in a dog with suspected primary nodal plasmacytoma treated with surgical excision
Abstract An 8‐year‐old Staffordshire bull terrier presented for left submandibular lymphadenopathy. Cytology showed a monomorphic population of mature plasma cells suggestive of plasma cell neoplasia. On physical examination, no other lymphadenomegaly, cutaneous or oral lesions were found.
Celia Figueroa‐González+4 more
wiley +1 more source
Revolutions at the frontline of multiple myeloma treatment: lessons and challenges to finding a cure. [PDF]
Kort J+3 more
europepmc +1 more source
Antisense inhibition of macrophage inflammatory protein 1-α blocks bone destruction in a model of myeloma bone disease [PDF]
Sun Jin Choi+6 more
openalex +1 more source
Biomarkers of Cellular Senescence in Type 2 Diabetes Mellitus
In cohorts of lean controls, obese participants without Type 2 Diabetes Mellitus (T2DM) and obese T2DM participants, we find that T‐cell expression of senescence biomarkers is altered only in the T2DM participants and not with obesity alone. Moreover, high T‐cell p16 expression in the T2DM participants is associated with impaired bone cortical indices.
Caroline Hoong+9 more
wiley +1 more source
Transcriptional analysis of BMP2 and BMP6 in patients with newly diagnosed multiple myeloma. [PDF]
Stoikos P+5 more
europepmc +1 more source
Sperm protein 17 (Sp17) in multiple myeloma: opportunity for myeloma-specific donor T cell infusion to enhance graft-versus-myeloma effect without increasing graft-versus-host disease risk [PDF]
Maurizio Chiriva‐Internati+5 more
openalex +1 more source
Zosteriform Primary Cutaneous Marginal Zone Lymphoma—A Case Report
ABSTRACT We report a case of zosteriform PCMZL presenting in a T3–T4 dermatomal distribution not previously described in the literature. Although the varicella zoster virus was not detected in this case, late diagnosis of the acute eruption of zoster or even preceding zoster ‘sine herpete’ cannot be excluded as antigenic triggers.
Natalie Teh+4 more
wiley +1 more source
Polymorphisms in Necroptosis Pathway Genes: Novel Prognostic Markers for Multiple Myeloma Treatment Outcomes. [PDF]
Sokołowski M+4 more
europepmc +1 more source