Results 321 to 330 of about 5,867,860 (378)

Beyond bacterial defences: the role of lysozyme in cancer

open access: yesClinical and Translational Medicine, Volume 16, Issue 2, February 2026.
Lysozyme (LYZ) is a multi‐functional secreted factor that encompasses both antibacterial and immunomodulatory functions. Emerging evidence highlights its complex role in tumour progression by directly influencing tumour cells and modulating the immune microenvironment.
Lei Wang   +4 more
wiley   +1 more source

Novel proteomic characterization of multiple myeloma bone marrow interstitial fluid links prognosis to coagulation pathways. [PDF]

open access: yesClin Proteomics
Cutler S   +10 more
europepmc   +1 more source

Tofacitinib‐Induced Weight Gain in Context: comment on the article by Wollenhaupt et al.

open access: yes
ACR Open Rheumatology, Volume 8, Issue 2, February 2026.
Andriko Palmowski   +4 more
wiley   +1 more source

Metabolic reprogramming of efferocytosis in the tumour microenvironment: From apoptotic‐cell clearance to therapeutic targeting

open access: yesClinical and Translational Medicine, Volume 16, Issue 2, February 2026.
This review systematically deconstructs the pathological efferocytic—metabolic axis in tumours, framing it as a three‐stage, self‐reinforcing cycle: from metabolite‐driven macrophage recruitment, through hijacked surface recognition, to post‐phagocytic metabolic reprogramming that locks in immunosuppression.
Qianlu Yang, Jie Yan, Qianxi Yang
wiley   +1 more source

DNTTIP1 drives leukaemogenesis through MiDAC‐mediated epigenetic silencing of BMF

open access: yesClinical and Translational Medicine, Volume 16, Issue 2, February 2026.
DNTTIP1 cooperates with SP1 to recruit HDAC1/2, leading to BMF silencing and reduced competitive binding of BMF to BCL2.This suppresses autophagy and apoptosis, promoting leukaemic cell survival. Targeting the DNTTIP1‐HDAC1/2‐BMF axis reactivates BMF and induces anti‐leukaemic effects.
Ruolin Xiu   +12 more
wiley   +1 more source

Single-cell RNA sequencing reveals immune regulatory mechanisms and molecular therapeutic strategies in the microenvironment of multiple myeloma. [PDF]

open access: yesInt J Surg
Su Q   +13 more
europepmc   +1 more source

Therapeutic Potential of Exportin 1 and Aurora Kinase A Inhibition in Multiple Myeloma Cells. [PDF]

open access: yesHematol Rep
Okabe S   +6 more
europepmc   +1 more source

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