Results 161 to 170 of about 87,247 (298)

Cardiotoxicity of BRAF/MEK inhibitors

British Journal of Pharmacology, EarlyView.
Abstract Rapidly accelerated fibrosarcoma type B/B‐Raf proto‐oncogene, serine/threonine kinase (BRAF) and mitogen‐activated protein kinase (MEK) inhibitors have transformed outcomes in cancer therapy, particularly in melanoma. However, cardiovascular toxicities are increasingly recognized in real‐world clinical practice.
Katharina Seuthe, Valerie Lohner, Kevin Terre, Thomas Riffelmacher, Roman Pfister   +4 more
wiley   +1 more source

Diagnostic and prognostic value of neutrophil extracellular traps in sepsis and their correlation with inflammatory factors. [PDF]

BMC Infect Dis
Bao Z, Zhou J, Jiang J, Zhou X.
europepmc   +1 more source

Lactate‐Primed NETosis Modulates Hepatic Regeneration During Acute Liver Failure via the TLR9/KLF15/AJUBA Axis

Cell Proliferation, EarlyView.
This study elucidates a novel Kupffer cell‐neutrophil‐hepatocyte axis that drives metabolic‐immune crosstalk during acute liver failure. Specifically, lactate‐primed NETs release links metabolic reprogramming to NETosis‐induced regenerative failure in hepatocytes via the TLR9/KLF15/AJUBA axis.
Jin Guo, Xiaoya Zhang, Danmei Zhang, Chunxia Shi, Luwen Wang, Zuojiong Gong   +5 more
wiley   +1 more source

The Roles of Four Neutrophil-Derived Proteins as Non-Invasive Biomarkers in the Assessment of Inflammatory Bowel Disease. [PDF]

J Inflamm Res
Day AS.
europepmc   +1 more source

S1 Guideline: Therapy of generalized pustular psoriasis

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary The S1 guideline “Therapy of generalized pustular psoriasis (GPP)” is a German guideline developed in accordance with the criteria of the AWMF. The full version addresses clinical presentation, pathogenesis, diagnosis and differential diagnosis, comorbidities, and therapy.
Rotraut Mößner, Neda Cramer, Sascha Gerdes, Ulrike Hüffmeier, Andreas Körber, Kai Krause, Christian Kromer, Katharina Antonia Langen, Sandra Philipp, Knut Schäkel, Michael P. Schön, Michael Schultheis, Lukas Sollfrank, Petra Staubach, Michael Sticherling, Johannes Wohlrab, Dagmar Wilsmann‐Theis, Cornelia Paul   +17 more
wiley   +1 more source

Prevalence and Correlates of Environmental Enteric Dysfunction Among Young Children in Bangladesh. [PDF]

Matern Child Nutr
Thompson L, Arnold CD, Long JM, Westcott JLE, Sthity RA, Khandaker AM, Islam MM, Black RE, Krebs NF, McDonald CM.   +9 more
europepmc   +1 more source

Histopathological analysis of CD163 and myeloperoxidase expression in neutrophil-rich dermatoses. [PDF]

An Bras Dermatol
Quintella DC, Milito CB, Cuzzi T.
europepmc   +1 more source

Eosinophilia and Hypereosinophilia: A Practical Approach to Navigating a Broad Differential Diagnosis

European Journal of Haematology, EarlyView.
ABSTRACT Eosinophilia, defined as an absolute eosinophil count (AEC) of ≥ 0.5 × 109/L, is a frequently encountered finding with a vast spectrum of potential underlying etiologies. Hypereosinophilia (HE) is defined as AEC > 1.5 × 109/L and may become life‐threatening when eosinophil‐induced organ damage occurs, defining the hypereosinophilic syndrome ...
Stijn Wigerinck, Peter Vandenberghe
wiley   +1 more source

Immature Neutrophil Phenotype and Enhanced Myeloperoxidase in Male Patients With Chronic Kidney Disease and Cardiovascular Comorbidity. [PDF]

Acta Physiol (Oxf)
Vondenhoff S, Antwerpen A, Junho CVC, Martin P, Hourtz S, Zou J, Kurt B, Haas C, Fleig S, Schulte C, Lauxen J, Wessiepe M, Späte-Schulze U, Kramann R, Floege J, Soehnlein O, Jankowski J, Goettsch C, Döring Y, Kahles F, Marx N, Baaten CCFMJ, Noels H.   +22 more
europepmc   +1 more source

Myeloperoxidase and anti-myeloperoxidase autoantibodies in renal inflammation [PDF]

, 2021
openaire   +1 more source