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NanoArrayPAD-X: Nanoprobe Array and 3D-µPAD for the Simultaneous Detection of Respiratory Pathogens and Biomarkers at the Point of Care. [PDF]
Biosensors (Basel)Vaquer A +13 more
europepmc +1 more source
Causal association between neutrophil extracellular traps and rheumatoid arthritis: A 2-sample bidirectional Mendelian randomization study. [PDF]
Medicine (Baltimore)Luo J, Li X, Wang X, Yuan J.
europepmc +1 more source
Association of Oxidative Stress Markers with Cardio-Kidney-Metabolic Parameters and Cardiovascular Disease in Patients with Type 2 Diabetes Mellitus. [PDF]
BiomoleculesRoumeliotis S +5 more
europepmc +1 more source
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Current Opinion in Hematology, 2000
This review covers recent advances in the biology of myeloperoxidase. Mechanisms of posttranslational processing and how these fail in some of the common deficiency mutants are discussed. We also review the enzymology that points to myeloperoxidase having a number of physiologic substrates in addition to chloride and the evidence that it produces ...
C C, Winterbourn +2 more
openaire +3 more sources
This review covers recent advances in the biology of myeloperoxidase. Mechanisms of posttranslational processing and how these fail in some of the common deficiency mutants are discussed. We also review the enzymology that points to myeloperoxidase having a number of physiologic substrates in addition to chloride and the evidence that it produces ...
C C, Winterbourn +2 more
openaire +3 more sources
Proceedings of the Association of American Physicians, 1999
Phagocytes respond to stimulation with a burst of oxygen consumption, and much, if not all, of the extra oxygen consumed in the respiratory burst is converted first to the superoxide anion and then to hydrogen peroxide (H2O2). Myeloperoxidase (MPO), which is released from cytoplasmic granules of neutrophils and monocytes by a degranulation process ...
K, Saito, Y, Nakamura
openaire +4 more sources
Phagocytes respond to stimulation with a burst of oxygen consumption, and much, if not all, of the extra oxygen consumed in the respiratory burst is converted first to the superoxide anion and then to hydrogen peroxide (H2O2). Myeloperoxidase (MPO), which is released from cytoplasmic granules of neutrophils and monocytes by a degranulation process ...
K, Saito, Y, Nakamura
openaire +4 more sources
Hematology/Oncology Clinics of North America, 1988
MPO activity is critical for optimal microbicidal activity of normal PMNs. In the absence of MPO, auxiliary mechanisms protect most MPO-deficient hosts from clinically significant sequelae, except for some persons with diabetes mellitus who suffer severe candidal disease.
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MPO activity is critical for optimal microbicidal activity of normal PMNs. In the absence of MPO, auxiliary mechanisms protect most MPO-deficient hosts from clinically significant sequelae, except for some persons with diabetes mellitus who suffer severe candidal disease.
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Diagnostic Assays for Myeloperoxidase and Myeloperoxidase Deficiency
2014Neutrophils (PMN) represent the dominant cell in the acute response to microbial infection and can contribute to some of the tissue damage that accompanies sterile inflammation. Effective antimicrobial activity in neutrophil phagosomes reflects the combined action of soluble agents in plasma with PMN-derived reactive oxygen species and granule proteins,
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Neuromediated Myeloperoxidase Deficiency
Archives of Pediatrics & Adolescent Medicine, 1990Sir.—In the March 1925 issue ofAJDC, Sato1reported changes in the blood myeloid leukocytes, resulting from injuries to certain parts of the brain produced experimentally in animals. Only those rabbits that had received bilateral thermocautery lesions of the corpora striata showed a myeloperoxidase (MPO)–negative reaction of neutrophils in fresh blood ...
P, Cocchi, C, Cocchi
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