Results 91 to 100 of about 39,467 (264)

Sex matters in CSU: Women face greater burden and poorer urticaria control, especially in midlife—CURE insights

open access: yesJournal of the European Academy of Dermatology and Venereology, EarlyView.
Chronic spontaneous urticaria affects more females than males, with predominance starting at age 31. The rates of several symptoms, including angioedema, sleep disturbance and systemic symptoms, are significantly higher in females than in males. Overall, females face greater burden and poorer urticaria control.
Emek Kocatürk   +40 more
wiley   +1 more source

Improved Diagnosis of the Transition to JAK2V617F Homozygosity: The Key Feature for Predicting the Evolution of Myeloproliferative Neoplasms [PDF]

open access: yes, 2013
Most cases of BCR-ABL1-negative myeloproliferative neoplasms (MPNs), essential thrombocythemia, polycythemia vera and primary myelofibrosis are associated with JAK2V617F mutations.
Bianchini, Michele   +6 more
core   +3 more sources

Patient characteristics and clinical determinants of outpatient red cell transfusions

open access: yesTransfusion, EarlyView.
Abstract Background There is a knowledge gap in the outpatient transfusion practice of red blood cells (RBC) according to optimal trigger, dose, and interval as well as which patients are in need of outpatient transfusion. Study Design and Methods This single‐center retrospective analysis investigates RBC transfusion practices in 804 patients with 5591
Nora Hemesath   +10 more
wiley   +1 more source

Frequency of heterozygous TET2 deletions in myeloproliferative neoplasms

open access: yesCancer Management and Research, 2010
Joseph Tripodi1, Ronald Hoffman1, Vesna Najfeld2, Rona Weinberg31The Myeloproliferative Disorders Program, Tisch Cancer Institute, Department of Medicine and 2Department of Medicine and Pathology, Mount Sinai School of Medicine, 3The Myeloproliferative ...
Joseph Tripodi   +3 more
doaj  

Calreticulin: Challenges Posed by the Intrinsically Disordered Nature of Calreticulin to the Study of Its Function

open access: yesFrontiers in Cell and Developmental Biology, 2017
Calreticulin is a Ca2+-binding chaperone protein, which resides mainly in the endoplasmic reticulum but also found in other cellular compartments including the plasma membrane. In addition to Ca2+, calreticulin binds and regulates almost all proteins and
Lilian Varricchio   +8 more
doaj   +1 more source

Advancements in genetic analysis: Insights from a case study and review of next‐generation sequencing techniques for veterinary oncology applications

open access: yesVeterinary Clinical Pathology, EarlyView.
Abstract Acute myeloid leukemia (AML) poses significant challenges in veterinary medicine, with limited treatment options and poor survival rates. While substantial progress has been made in characterizing human AML, translating these advancements to veterinary practice has been hindered by limited molecular understanding and diagnostic tools. The case
R. Adam Harris   +5 more
wiley   +1 more source

Review of current classification, molecular alterations, and tyrosine kinase inhibitor therapies in myeloproliferative disorders with hypereosinophilia

open access: yesJournal of Blood Medicine, 2013
Violaine Havelange,1,2 Jean-Baptiste Demoulin1 1de Duve Institute, Université catholique de Louvain, Brussels, Belgium; 2Department of Hematology, Cliniques universitaires Saint-Luc, Université catholique de Louvain, Brussels, Belgium ...
Havelange V, Demoulin JB
doaj  

The Calreticulin gene and myeloproliferative neoplasms [PDF]

open access: yes, 2016
The Philadelphia negative myeloproliferative neoplasms include polycythaemia vera (PV), essential thrombocytopenia (ET) and primary myelofibrosis (PMF).
Clinton, Aoibhinn   +1 more
core   +1 more source

Alzheimer\u27s Disease and Down\u27s Syndrome: An Overview [PDF]

open access: yes, 2011
The association between Alzheimer\u27s Disease and Down\u27s Syndrome is well recognized through clinical observations and genetic studies. However, the exact nature and the implications of this link is far from clear as yet.
Desai, M.B.B.S., Dr.Devanshu
core   +1 more source

Adding low-dose antidepressants to interferon alpha treatment for chronic hepatitis C improved psychiatric tolerability in a patient with schizoaffective psychosis [PDF]

open access: yes, 2000
Treatment of chronic hepatitis C with interferon alpha (IFN-alpha) is relatively contraindicated in patients with psychiatric disorders because of possible severe psychiatric side effects.
Amann, B.   +5 more
core   +1 more source

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