Results 31 to 40 of about 39,467 (264)

Platelets as mediators of Thromboinflammation in chronic Myeloproliferative Neoplasms [PDF]

, 2019
Chronic myeloproliferative neoplasms (MPN) are stem cell disorders driven by mutations in JAK2, CALR, or MPL genes and characterized by myeloid proliferation and increased blood cell counts.
Heller, Paula Graciela, Marin Oyarzún, Cecilia Paola   +1 more
core   +1 more source

Failure of Splenectomy to Ameliorate Portal Hypertension in Myeloproliferative Disorders

Canadian Journal of Gastroenterology, 1994
The correct treatment of portal hypertension associated with myeloproliferative disorders remains uncertain. Splenectomy has been advocated by some to eliminate the forward flow component of the portal hypertension and thus reduce portal pressure.
Samuel S Lee, Guido Van Rosendaal, Thomas E Lay, James K Kelly, Graham F Pineo   +4 more
doaj   +1 more source

Myeloproliferative neoplasms working group consensus recommendations for diagnosis and management of primary myelofibrosis, polycythemia vera, and essential thrombocythemia

Indian Journal of Medical and Paediatric Oncology, 2015
According to the 2008 revision of the World Health Organization (WHO) classification of myeloid malignancies, philadelphia chromosome (Ph)-negative myeloproliferative neoplasms (MPNs) include clonal, hematologic disorders such as polycythemia vera ...
M B Agarwal, Hemant Malhotra, Prantar Chakrabarti, Neelam Varma, Vikram Mathews, Jina Bhattacharyya, Tulika Seth, K Gayathri, Hari Menon, P G Subramanian, Ajay Sharma, Maitreyee Bhattacharyya, Jay Mehta, A K Vaid, Sandeep Shah, Shyam Aggarwal, P K Gogoi, Reena Nair, Usha Agarwal, Subhash Varma, S. V. S. S. Prasad, Marie Therese Manipadam   +21 more
doaj   +1 more source

Markedly increased small-sized megakaryocytes and platelets count in the circulation with pseudo-hyperkalemia following splenectomy

European Journal of Medical Research, 2022
Megakaryocytes are common in the bone marrow and appear less often in circulation. Most studies on circulatory megakaryocytes have implicated myelodysplastic syndromes and myeloproliferative disorders because of disruption of the bone marrow barrier and ...
Guiying Li, Bin Wang, Dongyan Li, Rong Zhu, Xueyan Chen   +4 more
doaj   +1 more source

Essential Thrombocythemia's Role in the Complex Landscape of Vasculitis: A Case Report. [PDF]

Clin Case Rep
ABSTRACT Peripheral gangrenes have been sporadically documented as the initial presentation of essential thrombocythemia (ET), as exemplified in the preceding case reports. Nevertheless, the prevalence of vasculitis‐induced skin problems as the primary indication of ET has not been extensively examined.
Jafari Nakhjavani MR, Mirzohreh ST, Kolahi S, Hajialilo M, Jafarpour M, Ghasembaglou A, Sattary Oskouie MA, Pourlak T, Tahsini Tekantapeh S.   +8 more
europepmc   +2 more sources

Oncogenes in Myeloproliferative Disorders [PDF]

Cell Cycle, 2007
Myeloproliferative disorders (MPDs) constitute a group of hematopoietic malignancies that feature enhanced proliferation and survival of one or more myeloid lineage cells. William Dameshek is credited for introducing the term "MPDs" in 1951 when he used it to group chronic myeloid leukemia (CML), polycythemia vera (PV), essential thrombocythemia (ET ...
Ayalew Tefferi, D. Gary Gilliland, D. Gary Gilliland   +2 more
openaire   +3 more sources

Diagnostic and therapeutic considerations in idiopathic hypereosinophilia with warm autoimmune hemolytic anemia. [PDF]

, 2015
Hypereosinophilic syndrome (HES) encompasses numerous diverse conditions resulting in peripheral hypereosinophilia that cannot be explained by hypersensitivity, infection, or atopy and that is not associated with known systemic diseases with specific ...
Brys, Adam K, Sheth, Milan R, Sohn, David D, Sweidan, Alexander J   +3 more
core   +1 more source

Case Report: Free-Floating Intracoronary Thrombus: Who Is the Convict?

Frontiers in Oncology, 2022
In young patients, especially with no traditional coronary risk factors, hypercoagulable states may always be considered as an alternative cause of acute coronary syndromes.
Francesca Mantovani, Ambra Paolini, Andrea Barbieri, Giuseppe Boriani   +3 more
doaj   +1 more source

Myelopoiesis and Myeloproliferative Disorders

Veterinary Clinics of North America: Small Animal Practice, 1996
Myeloid cells arise from a common stem cell whose development is regulated by stimulatory and inhibitory growth factors. Pluripotential hematopoietic stem cells are most influenced by IL-3, GM-CSF, and stem cell factor while committed progenitor cells are regulated by variable concentrations of GM-CSF, G-CSF, M-CSF, IL-5, Epo, and Tpo.
Department of Physiological Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FloridaDepartment of Physiological SciencesCollege of Veterinary MedicineUniversity of FloridaGainesvilleFlorida ( host institution ), Raskin, Rose E.   +1 more
openaire   +4 more sources

Down syndrome-recent progress and future prospects [PDF]

, 2009
Down syndrome (DS) is caused by trisomy of chromosome 21 (Hsa21) and is associated with a number of deleterious phenotypes, including learning disability, heart defects, early-onset Alzheimer's disease and childhood leukaemia.
Adams, Adayev, Ahn, Ait Yahya-Graison, Altafaj, Antonarakis, Arron, Aylward, Aylward, Bartel, Belichenko, Bercovich, Best, Bliss, Brault, Canfield, Canzonetta, Carothers, Clark, Contestabile, Costa, de Graaf, De Vita, Denoeud, Dowjat, Draheim, E. M.C. Fisher, Ermak, Ermak, F. K. Wiseman, Fernandez, Freeman, Fuentes, Gerstein, Glasson, Granholm, Granholm, Groet, Guidi, Gwack, Harashima, Hasle, Hassold, Hill, Holland, Holtzman, Holtzman, Hunter, Hunter, Izraeli, Janicki, Johannsen, K. A. Alford, Kiyoi, Klusmann, Kuhn, Lai, Lee, Liang, Loos, Lorenzi, Mart  nez de Lagr  n, Maslen, Meng, Moore, Morice, Morris, Morrison, Murthy, Necchi, Nistor, O'Doherty, O'Donovan, O'Nuallain, Olson, Park, Pearlson, Prandini, Richtsmeier, Ryoo, Sato, Seo, Sethupathy, Stefansson, Sultan, Sussan, Toso, Tybulewicz, V. L.J. Tybulewicz, Wahab, Walters, Wechsler, Wegiel, Weis, Williams, Woods, Yang   +96 more
core   +2 more sources