Results 31 to 40 of about 3,367,821 (256)

Cardiovascular Disease in Myeloproliferative Neoplasms

JACC CardioOncology, 2022
Myeloproliferative neoplasms are associated with increased risk for thrombotic complications. These conditions most commonly involve somatic mutations in genes that lead to constitutive activation of the Janus-associated kinase signaling pathway (eg ...
O. Leiva, G. Hobbs, K. Ravid, P. Libby
semanticscholar   +1 more source

Chronic myeloproliferative disorders: A rarest case with oral manifestations and dental management

Journal of Indian Academy of Oral Medicine and Radiology, 2012
Chronic myeloproliferative disorders (CMPD) are rarest hematological disorders (malignant myeloid neoplasms). The three most common chronic myeloproliferative disorders are polycythemia vera, essential thrombocythemia and chronic idiopathic myelofibrosis.
Pritesh B Ruparelia, Kosha Pritesh Ruparelia, Rajan Shirolkar, Anurag Tripathi   +3 more
doaj   +1 more source

Bone Marrow Fibrosis in Chronic myeloid leukemia (CML) and other Myeloproliferative Disorders Evaluated by Using Special Histochemical Stains for Collagen.

مجلة كلية الطب, 2011
Background: It is still difficult to give a final diagnosis in chronic myeloproliferative disorders (CMPDs) because of the overlap of the common pathological and clinical features of these disorders like bone marrow fibrosis which is considered important
Ali Khalil I. Al-Khafaji, Haider H. Jaleel Al-Shammari, Salim R. Hamudi Al-Obeidi   +2 more
doaj   +1 more source

Feline primary erythrocytosis: a multicentre case series of 18 cats [PDF]

, 2018
A retrospective multicentre case series of feline primary erythrocytosis (PE) was evaluated. The aim was to gain better understanding of disease presentation and progression to guide management and prognostication. Case records were assessed for evidence
Balazs Szladovits, Barbara Glanemann, Hannah Darcy, Isuru Gajanayake, Katherine Simpson, Mayank Seth, McLornan D, Yvonne McGrotty   +7 more
core   +1 more source

Molecular pathogenesis of the myeloproliferative neoplasms

Journal of Hematology & Oncology, 2021
The Philadelphia negative myeloproliferative neoplasms (MPN) compromise a heterogeneous group of clonal myeloid stem cell disorders comprising polycythaemia vera, essential thrombocythaemia and primary myelofibrosis.
G. Greenfield, M. McMullin, K. Mills
semanticscholar   +1 more source

JAK2V617F-bearing vascular niche enhances malignant hematopoietic regeneration following radiation injury

Haematologica, 2018
Myeloproliferative neoplasms are clonal stem cell disorders characterized by hematopoietic stem/progenitor cell expansion. The acquired kinase mutation JAK2V617F plays a central role in these disorders.
Chi Hua Sarah Lin, Yu Zhang, Kenneth Kaushansky, Huichun Zhan   +3 more
doaj   +1 more source

Is porto sinusoidal vascular disease to be actively searched in patients with portal vein thrombosis? [PDF]

, 2019
Porto sinusoidal vascular liver disease (PSVD) and portal vein thrombosis (PVT) are distinct vascular liver diseases characterized, respectively, by an intrahepatic and a prehepatic obstacle to the flow in the liver portal system. PVT may also occur as a
D'Amati, G., Gioia, S., Nardelli, S., Ridola, L., Riggio, O.   +4 more
core   +1 more source

The pathobiology of thrombosis, microvascular disease, and hemorrhage in the myeloproliferative neoplasms.

Blood, 2021
Thrombotic, vascular, and bleeding complications are the most common causes of morbidity and mortality in the Philadelphia chromosome-negative myeloproliferative neoplasms (MPNs).
H. Hasselbalch, M. Elvers, A. Schafer
semanticscholar   +1 more source

Methylation of the suppressor of cytokine signaling 3 gene (SOCS3) in myeloproliferative disorders

Haematologica, 2008
Background The JAK2 V617F mutation can be found in patients with polycythemia vera, essential thrombocythemia and idiopathic myelofibrosis. Mutation or methylation of other components of JAK/STAT signaling, such as the negative regulators suppressor of ...
Nasios Fourouclas, Juan Li, Daniel C. Gilby, Peter J. Campbell, Philip A. Beer, Elaine M. Boyd, Anne C. Goodeve, David Bareford, Claire N. Harrison, John T. Reilly, Anthony R. Green, Anthony J. Bench   +11 more
doaj   +1 more source

Erythematous Macular Eruption in an Older Woman [PDF]

, 2019
A white woman in her 70s with advanced Alzheimer disease was referred to the hematology clinic for evaluation of a high hemoglobin level (169 g/L; normal range, 120-160 g/L) and red blood cell count (5.67 × 1012/L; normal range, 3.8-4.8 × 1012/L) as well
Kernohan, Neil, McLaughlin, David, Tauro, Sudhir   +2 more
core   +2 more sources