Results 41 to 50 of about 3,006,184 (303)

Markedly increased small-sized megakaryocytes and platelets count in the circulation with pseudo-hyperkalemia following splenectomy

open access: yesEuropean Journal of Medical Research, 2022
Megakaryocytes are common in the bone marrow and appear less often in circulation. Most studies on circulatory megakaryocytes have implicated myelodysplastic syndromes and myeloproliferative disorders because of disruption of the bone marrow barrier and ...
Guiying Li   +4 more
doaj   +1 more source

Splanchnic vein thrombosis in myeloproliferative neoplasms: Pathophysiology and molecular mechanisms of disease [PDF]

open access: yes, 2016
Myeloproliferative neoplasms (MPNs) are the most common underlying prothrombotic disorder found in patients with splanchnic vein thrombosis (SVT). Clinical risk factors for MPN-associated SVTs include younger age, female sex, concomitant hypercoagulable ...
How, Joan, Oh, Stephen T, Zhou, Amy
core   +2 more sources

Diagnostic and therapeutic considerations in idiopathic hypereosinophilia with warm autoimmune hemolytic anemia. [PDF]

open access: yes, 2015
Hypereosinophilic syndrome (HES) encompasses numerous diverse conditions resulting in peripheral hypereosinophilia that cannot be explained by hypersensitivity, infection, or atopy and that is not associated with known systemic diseases with specific ...
Brys, Adam K   +3 more
core   +1 more source

Down syndrome-recent progress and future prospects [PDF]

open access: yes, 2009
Down syndrome (DS) is caused by trisomy of chromosome 21 (Hsa21) and is associated with a number of deleterious phenotypes, including learning disability, heart defects, early-onset Alzheimer's disease and childhood leukaemia.
Adams   +96 more
core   +2 more sources

Coexistence of chronic lymphocytic leukemia and polycythemia vera: a case report and review of the literature

open access: yesAnnals of Saudi Medicine, 2016
Polycythemia vera is a Philadelphia chromosome-negative myeloproliferative neoplasm. Chronic lymphocytic leukemia is a monoclonal expansion of a CD5+ CD19+ B lymphocytes.
Serdal Korkmaz   +4 more
doaj   +1 more source

Fibroblast growth factor receptor signaling in hereditary and neoplastic disease: biologic and clinical implications. [PDF]

open access: yes, 2015
Fibroblast growth factors (FGFs) and their receptors (FGFRs) are transmembrane growth factor receptors with wide tissue distribution. FGF/FGFR signaling is involved in neoplastic behavior and also development, differentiation, growth, and survival.
Helsten, Teresa   +2 more
core   +2 more sources

Atypical pyoderma gangrenosum in a patient with osteomyelofibrosis [PDF]

open access: yesVojnosanitetski Pregled, 2007
Background. Atypical forms of pyoderma gangrenosum generally appear on the upper extremities; most frequently they are associated with myeloproliferative disorders, including osteomyelofibrosis.
Živanović Dubravka   +6 more
doaj   +1 more source

HDL and Glut1 inhibition reverse a hypermetabolic state in mouse models of myeloproliferative disorders

open access: yesJournal of Experimental Medicine, 2013
Elevating HDL levels reduces Glut1 expression, dampens myeloproliferation, and prevents fat loss in multiple mouse models.
E. Gautier   +10 more
semanticscholar   +1 more source

Tofacitinib Use in a Patient With Rheumatoid Arthritis and Polycythemia Vera: A Case Report. [PDF]

open access: yesClin Case Rep
ABSTRACT Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by synovial inflammation and joint destruction, whereas polycythemia vera (PV) is a myeloproliferative neoplasm driven by the Janus kinase (JAK)2 V617F mutation, resulting in erythrocytosis and increased thromboembolic risk.
Bogojevic M   +4 more
europepmc   +2 more sources

Erythromelalgia: An Uncommon Presentation Precipitated by Aspirin Withdrawal

open access: yesCase Reports in Medicine, 2012
Erythromelalgia is a rare disorder frequently associated with myeloproliferative disorders. We describe a case of elderly patient diagnosed with myeloproliferative disorder in remission.
Fatima Khalid   +4 more
doaj   +1 more source

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