Results 41 to 50 of about 39,467 (264)
Annals of Saudi Medicine, 2016 Polycythemia vera is a Philadelphia chromosome-negative myeloproliferative neoplasm. Chronic lymphocytic leukemia is a monoclonal expansion of a CD5+ CD19+ B lymphocytes.
Serdal Korkmaz +4 more
doaj +1 more source
Hyperkalemia in Clinical Practice, an Important Reminder of Testing Modality. [PDF]
Clin Case RepABSTRACT We describe a patient with hyperkalemia and ECG changes with persistent mild hyperkalemia without ECG changes following treatment. Their hyperkalemia was confounded by the presence of true hyperkalemia due to an acute kidney injury and pseudohyperkalemia due to significant thrombocytosis.
Turner AG, Vardesh DL.
europepmc +2 more sources
Fibroblast growth factor receptor signaling in hereditary and neoplastic disease: biologic and clinical implications. [PDF]
, 2015 Fibroblast growth factors (FGFs) and their receptors (FGFRs) are transmembrane growth factor receptors with wide tissue distribution. FGF/FGFR signaling is involved in neoplastic behavior and also development, differentiation, growth, and survival.
Helsten, Teresa +2 more
core +2 more sources
Idiopathic noncirrhotic portal hypertension: current perspectives [PDF]
, 2016 The term idiopathic noncirrhotic portal hypertension (INCPH) has been recently proposed to replace terms, such as hepatoportal sclerosis, idiopathic portal hypertension, incomplete septal cirrhosis, and nodular regenerative hyperplasia, used to describe ...
D'AMATI, Giulia +5 more
core +1 more source
Erythromelalgia: An Uncommon Presentation Precipitated by Aspirin Withdrawal
Case Reports in Medicine, 2012 Erythromelalgia is a rare disorder frequently associated with myeloproliferative disorders. We describe a case of elderly patient diagnosed with myeloproliferative disorder in remission.
Fatima Khalid +4 more
doaj +1 more source
Targeting self-renewal pathways in myeloid malignancies [PDF]
, 2013 A fundamental property of hematopoietic stem cells (HSCs) is the ability to self-renew. This is a complex process involving multiple signal transduction cascades which control the fine balance between self-renewal and differentiation through ...
Copland, M., Sands, W.A., Wheadon, H.
core +2 more sources
JAK2 Inhibition: Reviewing a New Therapeutical Option in Myeloproliferative Neoplasms
Advances in Hematology, 2012 JAK2 is a tyrosine kinase gene that plays an essential role in the development of normal haematopoiesis. Hyperactivation of JAK2 occurs in myeloproliferative neoplasms by different mechanisms.
Mar Bellido, Peter A. W. te Boekhorst
doaj +1 more source
Orbital myeloid sarcoma (chloroma): Report of 2 cases and literature review
American Journal of Ophthalmology Case Reports, 2020 Purpose: Myeloid sarcoma (MS) of the orbit is an uncommon condition in occurring in children, generally coupled to myeloproliferative neoplasms. Observations: We describe two rare cases of orbital MS in young boys with aggressive local symptoms but ...
Mohammad A. AlSemari +11 more
doaj +1 more source
Arthritis &Rheumatology, EarlyView.Objective Vacuoles E1 enzyme X‐linked autoinflammatory somatic syndrome (VEXAS) is a recently identified rare genetic disorder associated with somatic mutations in the UBA1 gene. VEXAS presents with a combination of inflammatory and hematologic manifestations, leading to increased morbidity and mortality.
Arsene M. Mekinian +111 more
wiley +1 more source
Haematologica, 2013 Myeloproliferative disorders are associated with increased risk of thrombosis and vascular complications. The pathogenesis of these complications is not completely known.
Margarita Hurtado-Nedelec +8 more
doaj +1 more source