Results 131 to 140 of about 8,496 (180)

The action of neurotensin on single myenteric neurones

European Journal of Pharmacology, 1979
The action of neurotensin was studied on single myenteric neurones within ganglia of the myenteric plexus isolated from the guinea-pig ileum. Drugs were applied by adding them to the perfusing Krebs solution. Extracellular recording with glass suction electrodes indicated that neurotensin (100 pM-300 nM) caused a dose-dependent excitation of about 50 ...
J T, Williams, Y, Katayama, R A, North
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Aging of the myenteric plexus: neuronal loss is specific to cholinergic neurons

Autonomic Neuroscience, 2003
Neuron loss occurs in the myenteric plexus of the aged rat. The myenteric plexus is composed of two mutually exclusive neuronal subpopulations expressing, respectively, nitrergic and cholinergic phenotypes. The goal of the present study, therefore, was to determine if neuron loss is specific to one phenotype, or occurs in both.
Robert J, Phillips, Elizabeth J, Kieffer, Terry L, Powley   +2 more
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Calcium signalling and removal mechanisms in myenteric neurones

Neurogastroenterology & Motility, 2002
To characterize further the Ca2+ signalling mechanisms of myenteric neurones, we studied the effect of thapsigargin, a blocker of the Ca2+‐store ATPase, and the mechanisms involved in restoring the intracellular Ca2+ concentration ([Ca2+]i) after activation.
P, Vanden Berghe, L, Missiaen, J, Janssens, J, Tack   +3 more
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Effects of morphine on myenteric plexus neurones

Neuropharmacology, 1976
Abstract Intracellular recordings were made from neurones in the isolated myenteric plexus of the guinea-pig ileum. Approximately 50% of neurones responded to bath application of normorphine (10 nM−1 μM) with an immediate hyperpolarization. The hyperpolarization was usually associated with a fall in membrane resistance. The effect reversed on washing
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Distribution of muscarinic receptors on cultured myenteric neurons

Brain Research, 1984
The distribution of neurotransmitter receptors over the neuronal cell surface remains an outstanding question in neurobiology. In this study we have used autoradiographic procedures to localize muscarinic receptors on living cultures of enteric neurons, using the specific irreversible muscarinic ligand, [3H]propylbenzilylcholine mustard ([3H]PrBCM ...
N J, Buckley, G, Burnstock
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An intracellular study of myenteric neurons in the mouse colon

Journal of Neurophysiology, 1986
Intracellular recordings have been made in vitro from the myenteric neurons of the distal colon of normal littermates of the piebald-lethal mouse. Out of a total of 90 neurons, 82 were classified as S/type 1 cells and 8 as AH/type 2 cells. Seventy-eight out of 82 S cells showed spontaneous fast excitatory postsynaptic potentials (EPSPs) sensitive to d-
K, Furukawa, G S, Taylor, R A, Bywater
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Interactions between serotonin and cisapride on myenteric neurons

European Journal of Pharmacology, 1985
Intracellular recording methods were used to investigate the interactions between serotonin (5-HT) and cisapride on myenteric neurons of guinea-pig small intestine. Serotonin had three actions on the neurons. One was a slowly rising depolarization associated with increased input resistance and discharge of spikes that lasted six or more times longer ...
P R, Nemeth, C A, Ort, D H, Zafirov, J D, Wood   +3 more
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Noradrenergic innervation of serotoninergic neurons in the myenteric plexus

Journal of Comparative Neurology, 1987
AbstractThe monoaminergic innervation of the guinea pig small intestine was investigated to determine if there is an anatomical basis for the hypothesis that serotoninergic and noradrenergic neurons physiologically interact in the enteric nervous system.
M D, Gershon, D L, Sherman
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Synaptic activity of myenteric neurons in tissue culture

Journal of the Autonomic Nervous System, 1985
Intracellular recordings were made from myenteric neurons of the guinea-pig caecum grown in tissue culture. The experiments were carried out on cultures older than 15 days, in which the neurons formed ganglion-like aggregates with many interconnecting nerve fibres.
M, Hanani, G, Burnstock
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Neuronal and Non-Neuronal Plasticity in the Rat Following Myenteric Denervation

1997
The plasticity of the enteric nervous system in adulthood has always been a field of research of the greatest interest. Many experimental models have been developed, allowing to investigate the importance of the peripheral field of innervation in the control of growth and differentiation of enteric neurons during postnatal life (Filogamo, 1987 ...
C, Cracco, G, Filogamo
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