Spatial transcriptome analysis of myenteric plexus and intestinal epithelium of colon in patients with Parkinson’s disease [PDF]
Acta Neuropathologica CommunicationsAlpha-synuclein (AS) accumulation is found in the nerve plexuses of the gastrointestinal tract in patients with Parknison’s disease (PD). Moreover, alterations in microbiome composition and its metabolites were confirmed in the colon of patients with PD.
Chaewon Shin +8 more
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Unusual Histology of Eosinophilic Myenteric Ganglionitis: A Case Report [PDF]
Journal of Pathology and Translational Medicine, 2017 Eosinophilic myenteric ganglionitis is a disorder characterized by infiltration of the Auerbach myenteric plexus by eosinophils. As a cause of chronic intestinal pseudo-obstruction (CIPO), eosinophilic myenteric ganglionitis has been rarely reported and ...
Hyekyung Lee +4 more
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Sympathetic Pathways Target Cholinergic Neurons in the Human Colonic Myenteric Plexus [PDF]
Frontiers in Neuroscience, 2022 BackgroundThe sympathetic nervous system inhibits human colonic motility largely by effects on enteric neurons. Noradrenergic axons, which branch extensively in the myenteric plexus, are integral to this modulatory role, but whether they contact specific
Dominic R. Parker +9 more
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Age-Related Loss of GPR68 and Calretinin Immunoreactive Neurons Within the Mucosa, Not the Myenteric Plexus of Human Colon [PDF]
British Journal of Biomedical ScienceBackgroundThe G protein-coupled receptor 68 (GPR68) detects variations in extracellular pH, and has potential roles in homeostasis and responses to ischaemia and inflammation within different organs, including the gastrointestinal tract.
Nicholas Baidoo +6 more
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The P2Y1 receptor in the colonic myenteric plexus of rats and its correlation with opioid-induced constipation [PDF]
BMC GastroenterologyThis study was designed to explore the expression changes of P2Y1 receptors in the distal colonic myenteric layer of rats. An opioid induced constipation(OIC) rat model was generated by intraperitoneal (i.p) injection of loperamide.
Yuqiong Zhao +6 more
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Quantitative morphometric analysis of the myenteric nervous plexus ganglion structures along the human digestive tract [PDF]
Vojnosanitetski Pregled, 2016 Background/Aim. All the functions of the digestive system are controlled, guided and initiated by the autonomic nervous system. A special part of this system placed in the wall of the gastrointestinal tract is known as the enteric or ...
Mandić Predrag +5 more
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Evidence for a glutamatergic neural pathway in the myenteric plexus
American Journal of Physiology-Gastrointestinal and Liver Physiology, 1991 The objective of this study was to determine whether L-glutamate (L-Glu) may serve as a neurotransmitter candidate in the guinea pig myenteric plexus.
C. Owyang, J. W. Wiley, Y. X. Lu
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Systematic Characterisation of GLP-1R in Human Enteric Nervous System: Implications for GLP-1 as a Key Regulator of Colonic Activity. [PDF]
J NeurochemGlucagon‐like peptide‐1 (GLP‐1) regulates glucose homeostasis, appetite and gastrointestinal motility through activation of the GLP‐1 receptor (GLP‐1R). Although central mechanisms are well established, the anatomical distribution of GLP‐1R within the human enteric nervous system (ENS) has not been fully defined.
Dontamsetti KD, Aktar R, Peiris M.
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An immunohistochemical study of the myenteric plexus in idiopathic achalasia
Journal of Clinical Gastroenterology, 2010 Background: Achalasia is a primary esophageal motor disorder characterized by degenerative changes of the myenteric plexus. The pathophysiologic abnormalities may be the final result of several intermeshing mechanisms, and more than one single factor may
De Santo E. +7 more
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Brazilian Journal of Medical and Biological Research, 1997 The myenteric plexus of the digestive tract of the wild mouse Calomys callosus was examined using a histochemical method that selectively stains nerve cells, and the acetylcholinesterase (AChE) histochemical technique in whole-mount preparations ...
L.B.M. Maifrino +3 more
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