Results 151 to 160 of about 17,260 (285)

A Phase 2 Trial of Frexalimab, a CD40L Antagonist, in Adolescents and Adults With Recent‐Onset Type 1 Diabetes (FABULINUS): Rationale and Study Design

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Introduction Type 1 diabetes (T1D) is a chronic autoimmune disease, characterised by progressive destruction of the insulin‐producing pancreatic β‐cells. Preserving remaining β‐cells at the time of diagnosis may improve long‐term outcomes. Frexalimab is a humanised monoclonal antibody specific for CD40L undergoing evaluation for treatment of ...
Andriy Cherkas   +11 more
wiley   +1 more source

Functional myocardial bridging resulting in sub-endocardial anterior myocardial infarction

open access: yesHellenic Journal of Cardiology, 2023
Linda Kimani   +4 more
doaj   +1 more source

Myocardial Bridging and Cardiac Arrest. [PDF]

open access: yesJACC Case Rep
Iyer KV   +9 more
europepmc   +1 more source

Evaluation of the Safety, Efficacy and Pharmacokinetics of BGM0504 in Chinese Adults With Type 2 Diabetes: A Multicentre, Randomised, Controlled and Double‐Blind Phase II Trial

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aim This study aimed to evaluate its safety, tolerability, pharmacokinetics, pharmacodynamics and efficacy in Chinese adults with T2DM and to preliminarily compare its efficacy and safety with semaglutide through multiple subcutaneous injections. Materials and Methods In this multicentre, randomised, placebo‐controlled and semaglutide‐positive‐
Ping Jin   +9 more
wiley   +1 more source

Intracoronary Electrocardiography During Dobutamine Stress for Functional Assessment of Myocardial Bridging. [PDF]

open access: yesJACC Case Rep
Miyazaki Y   +9 more
europepmc   +1 more source

Thrombosis and Circulation: From Bench to Bedside

open access: yes
Thrombosis and Circulation Research, EarlyView.
Zhenguo Zhai
wiley   +1 more source

Proteomic Profiling Captures Residual Cardiovascular Risk Beyond the PREVENT Model in Individuals With Cardiovascular–Kidney–Metabolic Syndrome Stages 2–3

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Background Cardiovascular–kidney–metabolic (CKM) syndrome reflects complex pathobiological interactions among metabolic disorders, kidney injury, and cardiovascular disease (CVD). Stages 2 and 3 represent critical phases of disease progression characterised by high pathological heterogeneity.
Xuefei Han   +4 more
wiley   +1 more source

Real-world presentation of myocardial bridging in the cath-lab: a case series. [PDF]

open access: yesEur Heart J Case Rep
D'Amario D   +7 more
europepmc   +1 more source

Real‐World Use of Emicizumab in Patients With Acquired Haemophilia A: An Interim Safety Analysis of a Large‐Scale Post‑Marketing Surveillance Study

open access: yesHaemophilia, EarlyView.
ABSTRACT Introduction Acquired haemophilia A (AHA) is a rare autoimmune disorder where the development of autoantibodies to factor (F)VIII neutralise its function, leading to bleeding. Emicizumab has been approved for treating AHA in Japan. Aim This post‐marketing study was performed to primarily examine the use and safety of emicizumab, and indirectly
Midori Shima   +8 more
wiley   +1 more source

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