Results 171 to 180 of about 88,408 (209)

Treg‐stromal cell axis in tissue repair and autoimmune diseases: Mechanisms and clinical translation

Rheumatology &Autoimmunity, EarlyView.
The Treg‐stromal cell axis as a central regulator of tissue repair and immune tolerance. Under physiological conditions, bidirectional communication between Tregs and stromal cells—mediated by cell‐surface molecular contacts, anti‐inflammatory cytokines, and extracellular vesicles—orchestrates inflammation resolution, immune tolerance, and complete ...
Peiyan Zhang, Rongyuan Gao, Zhaohui Zheng   +2 more
wiley   +1 more source

Circulating excitation-contraction coupling proteins and incident cardiovascular outcomes: associations and incremental predictive performance in the UK Biobank. [PDF]

Front Cardiovasc Med
Hu D, Gao Y, Wang J, Guo Q, Shi Z, Chen D, Xia D, Li M, Wang X, Geng B.   +9 more
europepmc   +1 more source

Potential value of slow‐wave sleep in management of chronic insomnia disorder

Sleep Research, EarlyView.
Abstract Chronic insomnia disorder (CID), acknowledged as the most common sleep disorder, has traditionally been diagnosed and managed with a focus on reducing sleep onset latency and extending total sleep duration. However, the critical importance of slow‐wave sleep (SWS), a key indicator of objective sleep quality, has been largely overlooked in ...
Liping Zhang, Qi Wu, Mengmeng Fan, Xianchao Zhao, Changjun Su   +4 more
wiley   +1 more source

Cardio-renal dysfunction in prediabetes and early type 2 diabetes: insights from myocardial strain and renal Doppler assessment. [PDF]

BMC Cardiovasc Disord
Atef A, Fayed A, El-Haddad H, Fathy M, El Deeb H.   +4 more
europepmc   +1 more source

Cell‐Based Micro/Nanorobots: From Living Carriers to Living Therapeutic Specialists

SmartBot, EarlyView.
Cell‐based micro/nanorobots integrate evolutionarily acquired biological intelligence with engineered capabilities, offering new opportunities for precision medicine in vivo. However, the complex physiological environments of different organs pose significant challenges to their clinical translation.
Junfeng Wu, Zhaoyu Zhang, Ke Xu, Enkuo Li, Yuting Cui, Yuting Zhou, Huanyu Zhou, Beipei Zhang, Shuai Jiang, Xiaodong Wang, Jialin Jiang, Lianqing Liu, Niandong Jiao   +12 more
wiley   +1 more source

The functional impact of myofiber macroscopic organization and disarray in computational models of the murine heart. [PDF]

PLoS Comput Biol
Guastamacchia C, Piersanti R, Giardini F, Coppini R, Ferrantini C, Dede' L, Sacconi L, Regazzoni F.   +7 more
europepmc   +1 more source

Cardiomyocyte Membrane‐Camouflaged Spinach Nano‐Thylakoids Enhance Myocardial Energy Metabolism and Ameliorate Heart Failure

Small, EarlyView.
Schematic illustration of the construction of MM‐NTU, its cardiac‐targeting behavior, and its light‐activated therapeutic mechanism. Thylakoids isolated from spinach chloroplasts were processed into nano‐thylakoid units (NTU) and further camouflaged with cardiomyocyte membranes to generate MM‐NTU.
Haohui Fan, Bei Song, Chengyun Liu, Peiyu Zhong, Quan Zhou, Xiaofang Zhao, Guangyu Gao, Xinyue Zhang, Xueke Guang, Tianci Yao, Ting Liu, Hao Zhang, Xinqi Diao, Weilin Lu   +13 more
wiley   +1 more source

Heart Failure with Reduced versus Preserved Ejection Fraction: Molecular Mechanisms, Immunologic Pathways, Current Therapies, and Future Directions. [PDF]

Arch Intern Med Res
Kim E, Agrawal DK.
europepmc   +1 more source

Hemodynamic Effects of Prolonged Apneic Oxygenation in Laryngologic Surgery: A Randomized Controlled Pilot Trial

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Limited data exist on cardiocirculatory responses associated with extended periods of apnea during administration of high‐flow nasal oxygen for laryngologic surgery (apneic oxygenation with HFNO, AO‐HFNO). The possibility of hemodynamic compromise in the settings of acute hypercapnia, respiratory acidosis, hyperoxia, and IV ...
Vladimir Nekhendzy, Hendrikus J. Lemmens, Amit R. Saxena, Brita M. Mittal, Edward J. Damrose, C. Kwang Sung, Raffick Bowen   +6 more
wiley   +1 more source

Development of a Predictive Model for Patient Compliance in Enhanced Recovery After Surgery (ERAS) Programs for Colorectal Surgery

World Journal of Surgery, EarlyView.
The newly developed compliance model will enable early identification of patients at risk of low adherence, thus supporting personalized perioperative management and improved recovery outcomes. ABSTRACT Background Enhanced recovery after surgery (ERAS) programs optimize perioperative care to reduce surgical stress and improve recovery.
Anas Taha, Bushra Mohandes, Michael Drew Honaker, Stephanie Taha‐Mehlitz, Shantanu Roy, Vincent Ochs, Otto Kollmar, Robert Rosenberg, Philippe C. Cattin   +8 more
wiley   +1 more source