Results 181 to 190 of about 218,133 (348)

miR-483-3p targets FGFR2 to inhibit cardiomyocyte pyroptosis NLRP3/Caspase-1/GSDMD signaling axis and reduce myocardial fibrosis [PDF]

, 2023
Xiangwei Lv, Liqin Chen, Zi-Feng He, Mingyu Zhang, Rongyan Chen, Tongtong Xu   +5 more
openalex   +1 more source

Cardiovascular‐Kidney‐Metabolic Syndrome in People With HIV: An Emerging Frontier for Clinical Pharmacology

Clinical Pharmacology &Therapeutics, EarlyView.
As antiretroviral therapy (ART) prolongs lifespans, people with HIV (PWH) face a new syndemic: Cardiovascular‐Kidney‐Metabolic (CKM) syndrome. Yet CKM in PWH is poorly characterized. Inflammation, complex pharmacokinetic (PK) alterations, ART‐associated metabolic effects, and gut dysbiosis amplify risk. Managing CKM increases medication burden, thereby
Aaron S. Devanathan, Thomas D. Nolin
wiley   +1 more source

Myocardial fibrosis

, 2020
Joachim Feger, Yuranga Weerakkody, Tom Foster   +2 more
openaire   +1 more source

Proteomics discovery in children and young adults with HIV identifies fibrosis, inflammatory, and immune biomarkers associated with myocardial impairment [PDF]

Josephine Harrington, Andrew W. McCrary, Maggie Nguyen, Winstone Nyandiko, Piers Barker, Myra Koech, Nathan M. Thielman, Michael J. Muehlbauer, Svati H. Shah, Gerald S. Bloomfield   +9 more
openalex   +1 more source

The effect of myocardial fibrosis on ventricular remodeling following valve replacement for severe aortic stenosis. A CMR study comparing transcatheter aortic valve implantation and surgical aortic valve replacement [PDF]

, 2012
Timothy Fairbairn, Christopher D Steadman, Adam N Mather, Manish Motwani, Daniel J. Blackman, Sven Plein, Gerry P McCann, John P. Greenwood   +7 more
openalex   +1 more source

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

ESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang, Umar Raza, Jia Song, Junyan Lu, Shun Yao, Xiaohong Liu, Wei Zhang, Shujuan Li   +7 more
wiley   +1 more source

Radiotherapy-induced diffuse myocardial fibrosis in early-stage breast cancer patients – multimodality imaging study with six-year follow-up [PDF]

, 2023
Mikko Moisander, Tanja Skyttä, Sari Kivistö, Heini Huhtala, Kjell Nikus, Vesa Virtanen, Pirkko‐Liisa Kellokumpu‐Lehtinen, Pekka Raatikainen, Suvi Tuohinen   +8 more
openalex   +1 more source

Association of COPD with adverse outcomes in heart failure patients with preserved ejection fraction

ESC Heart Failure, Volume 12, Issue 2, Page 799-808, April 2025.
Abstract We performed a systematic review and meta‐analysis to detect the impact of chronic obstructive pulmonary disease (COPD) on the prognosis of heart failure patients with preserved ejection fraction (HFpEF). We systematically screened eligible literature from three electronic databases, PubMed, EMBASE and Cochrane Library, up to April 2023.
Shuo Xu, Zhenbang Gu, Wengen Zhu, Shenghui Feng   +3 more
wiley   +1 more source

Cardiac overexpression of metallothionein rescues cold exposure-induced myocardial contractile dysfunction through attenuation of cardiac fibrosis despite cardiomyocyte mechanical anomalies

, 2012
Yingmei Zhang, Nan Hu, Yinan Hua, Kacy L. Richmond, Feng Dong, Jun Ren   +5 more
openalex   +2 more sources

Biomarkers of lung congestion and injury in acute heart failure

ESC Heart Failure, Volume 12, Issue 2, Page 781-789, April 2025.
Abstract Acute heart failure (AHF) classification and management are primarily based on lung congestion and/or hypoperfusion. The quantification of the vascular and tissue lung damage is not standard practice though biomarkers of lung injury may play a relevant role in this context.
Marco Guazzi, Gabriele Novello, Francesca Bursi, Anna Caretti, Noemi Furlotti, Ross Arena, Paola Argiento, Julio Núñez, Antoni Bayes‐Genis, Marco Metra   +9 more
wiley   +1 more source