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Fractional flow reserve as a surrogate for inducible myocardial ischaemia
Nature Reviews Cardiology, 2013Documentation of inducible myocardial ischaemia, related to the coronary stenosis of interest, is of increasing importance in lesion selection for percutaneous coronary intervention (PCI). Fractional flow reserve (FFR) is an easily understood, routine diagnostic modality that has become part of daily clinical practice, and is used as a surrogate ...
Tim P, van de Hoef +6 more
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CT Assessment of Myocardial Perfusion and Fractional Flow Reserve
Progress in Cardiovascular Diseases, 2015Coronary computed tomography angiography (CTA) offers a non-invasive method to detect coronary plaque and stenosis. However, to date, CTA has been most useful as a method of ruling out coronary artery disease (CAD) among patients with low to intermediate pretest probability of significant CAD.
Edward, Hulten +2 more
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On-line assessment of myocardial flow reserve
1996Myocardial blood flow is determined by two variables, namely, the resistance of the myocardial perfusion bed and the perfusion pressure. Maximal myocardial flow at any given pressure is a function of the total cross-sectional area of the coronary resistance vessels.
Martin J. Schalij +3 more
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Coronary Blood Flow Reserve and Myocardial Ischemia
2021Radionuclide myocardial perfusion imaging (MPI) using single-photon emission tomography (SPECT) or positron emission tomography (PET) is used worldwide in the assessment of patients with suspected or known coronary artery disease (CAD) [1–6]. In the recent decades, the better understanding of the coronary physiology and advances in technology have ...
Fernanda Erthal, Ronaldo Lima
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Possibilities and limitations of myocardial flow reserve
1994The concept of coronary flow reserve is important for the understanding of the physiological significance of obstructive coronary artery disease. The recent development of an angiographic method has made the measurement of coronary or myocardial flow reserve possible during routine coronary angiography.
Felix Zijlstra +2 more
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Fractional Flow Reserve-Guided Management in Stable Coronary Disease and Acute Myocardial Infarction: Recent Developments. [PDF]
European Heart Journal, 2015 Coronary artery disease (CAD) is a leading global cause of morbidity and mortality, and improvements in the diagnosis and treatment of CAD can reduce the health and economic burden of this condition.
David Corcoran +2 more
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Myocardial Perfusion and Fractional Flow Reserve
2013Myocardial CT perfusion imaging is a rapidly evolving technology that allows assessment of the functional significance of potentially obstructive coronary stenosis. The opportunity for quantification of myocardial perfusion is the greatest potential advantage of CT compared with other perfusion techniques.
K. Kitagawa, A. Erglis, M. Dewey
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Left Ventricular Hypertrophy, Myocardial Blood Flow and Coronary Flow Reserve
Cardiology, 2008In this review, the coronary haemodynamics of hypertrophic heart disease are discussed with reference to data published over the last 15 years. Coronary reserve is reduced in the presence of concentric cardiac hypertrophy, but is similar to normal in hypertrophic obstructive cardiomyopathy and aortic stenosis, despite marked left ventricular ...
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Myocardial Fractional Flow Reserve and Clinical Outcome
1997There is ample inferential evidence that patients with physiologically significant stenoses are at increased risk1. Patients with proven coronary artery disease and in whom signs of myocardial ischemia are observed at low workload have an adverse event rate which is four times higher than in those with similarly severe stenoses but in whom ischemia can
Nico H. J. Pijls, Bernard De Bruyne
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