Results 71 to 80 of about 3,950,906 (300)

Coronary flow reserve in severe aortic valve stenosis: a positron emission tomography study

, 2008
Objectives The purpose was to test whether, in patients with severe aortic stenosis, impaired myocardial blood flow reserve is dependent on myocardial hypertrophy and may improve after valve replacement.
Glauber M, Pratali L, Paradossi U, Carpeggiani C, L'Abbate A, Neglia D   +5 more
core   +1 more source

Magnetic Micro‐ and Nanorobots for Precision Thrombolysis: Design Strategies and Translational Challenges

Advanced Robotics Research, EarlyView.
Micro‐ and nanorobots for targeted thrombolysis. This perspective elaborates on the clinical indication of blood clot disorders and current limitations for treatment. As a novel, alternative solution, micro‐ and nanorobots can be used to treat and break down thrombi.
Joshua M. Mesfin, Yimo Yan, Nikola Cesarovic, Simone Schuerle   +3 more
wiley   +1 more source

Medium-term follow-up of intermediate coronary stenoses left unrevascularized based on myocardial fractional flow reserve findings

, 2002
Objective - Coronary stenoses of intermediate severity create difficulties in decision making when revascularization is concerned. Myocardial fractional flow reserve (mFFR), an accurate tool to identify physiological significance of individual coronary ...
Boyaci, B, Ozdemir, M, Dortlemez, O, Dortlemez, H, Timurkaynak, T, Cengel, A, Cemri, M, Yalcin, R   +7 more
core   +1 more source

Cell‐Based Biohybrid Micro/Nanorobots for Biotherapy

Advanced Robotics Research, EarlyView.
This review systematically evaluates cell‐based biohybrid micro/nanorobots (CB‐BMRs), highlighting their cell selection criteria, fabrication strategies, and diverse actuation modes. Furthermore, it surveys the promising therapeutic applications of CB‐BMRs in targeted cancer, thrombosis, and inflammation treatments, while comprehensively discussing ...
Lin Wang, Chenlu Liu, Yu Zhao, Chuanhua Li, Xuyang Chen, Shixiao Ding, Lizhou Dai, Guokun Wang, Tianlong Li, Jiaxin Li, Xuejia Liu, Haocheng Wang   +11 more
wiley   +1 more source

The impact of motion correction on quantitatively measured perfusion indices using cardiac-dedicated dynamic CZT-SPECT myocardial perfusion imaging

EJNMMI Physics
Background Dynamic myocardial perfusion imaging (MPI) with cadmium-zinc-telluride (CZT) cardiac-dedicated single-photon emission computed tomography (SPECT) enables the quantification of myocardial blood flow (MBF), myocardial flow reserve (MFR), and non-
Ajay Kumar Chaudhary, Fukai Zhao, Zekun Pang, Jianming Li   +3 more
doaj   +1 more source

The coronary flow reserve in patients with coronary slow flow and diagnostic value of myocardial work indices for coronary slow flow

Zhongguo Linchuang Yixue
ObjectiveTo explore the coronary flow reserve (CFR) in patients with coronary slow flow (CSF) and the diagnostic value of non-invasive myocardial work indices derived from echocardiography for CSF.
Qiaoyan WU, Zhenzhen DING, Huiping HOU, Mengzhang WU, Yongshi WANG, Weipeng ZHAO, Limin LUO   +6 more
doaj   +1 more source

Coronary vasodilator reserve persists despite tachycardia and myocardial ischemia

, 1987
During myocardial ischemia, we tested whether coronary blood flow would increase in response to tachycardia, thereby employing known coronary flow reserve.
G. A. Pantely, J. D. Bristow, E. O. McFalls, C. G. Anselone   +3 more
core   +1 more source

Chemical Screening Identifies Danofloxacin as a Self‐Renewal Agonist of Embryonic Stem Cells through Alleviation of HDAC1‐Mediated Deacetylation of Tert and Prdm10

Advanced Science, EarlyView.
This study identified Danofloxacin as a novel supporter of the maintenance of mouse embryonic stem cell (ESC) pluripotency. It functions partially by inhibiting HDAC1, which increases specific histone acetylation marks and activates key genes like Tert and Prdm10.
Yan Zhang, Junxiang Ji, Baoxing Dong, Zhenhua Zhu, Xucheng Lv, Peng Chen, Wenqiang Liu, Min Zhou, Shou‐Dong Ye   +8 more
wiley   +1 more source

Validation of Collateral Fractional Flow Reserve by Myocardial Perfusion Imaging [PDF]

Circulation, 2002
Background — Collateral fractional flow reserve (FFR coll ) is an index to quantify collateral blood flow, derived from coronary pressure measurements.
Hitoshi, Matsuo, Sachiro, Watanabe, Tohru, Kadosaki, Takahiko, Yamaki, Shinichiro, Tanaka, Shuusaku, Miyata, Tomonori, Segawa, Yukihiko, Matsuno, Masaaki, Tomita, Hisayoshi, Fujiwara   +9 more
openaire   +2 more sources

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source