Results 111 to 120 of about 644,429 (317)

An Implantable Phototriggered Prodrug Depot Patch Enables Actively Programmable Drug Release for Post‐Myocardial Infarction Therapy

Advanced Science, EarlyView.
An implantable phototriggered prodrug depot patch (iPDP) is presented that enables actively programmable drug release post‐implantation. Covalently conjugated prodrug ensures minimal leakage; illumination parameters serve as a code to precisely control dose per release.
Haipeng Lu, Kaicheng Deng, Zhang Zhang, Qirui Wang, Weijing Gao, Liyin Shen, Lei Zhang, Wenting Hu, Yang Zhu, Zhengwei Mao, Tanchen Ren   +10 more
wiley   +1 more source

Out-of-hours primary percutaneous coronary intervention for ST-elevation myocardial infarction is not associated with excess mortality: a study of 3347 patients treated in an integrated cardiac network [PDF]

, 2013
OBJECTIVES: Timely delivery of primary percutaneous coronary intervention (PPCI) is the treatment of choice for ST-segment elevation myocardial infarction (STEMI).
Rathod, Krishnaraj S., Gallagher, Sean M., Gallagher, SM, Bromage, Dan, Wragg, Andrew, Knight, Charles, Wragg, A, Jain, Ajay K., Archbold, AR, Rathod, KS, Bromage, DI, Knight, CJ, Jones, DA, Mathur, Anthony, Jones, Daniel A., Jain, AK, Whitbread, Mark, Whitbread, M, Mathur, A, Archbold, Andrew   +19 more
core   +1 more source

Beyond Potency: Emerging Determinants and Optimization Strategies Enhancing Therapeutic Efficacy of Adult Stem Cells

Advanced Science, EarlyView.
Adult stem cell therapy requires more than high in vitro potency. This review proposes a systems framework in which cell‐intrinsic programs, instructive microenvironmental cues, and pre‐/post‐delivery engineering are co‐designed under standardized translational rules.
Soo‐Rim Kim, Yun Jae Jung, Hwa‐Yong Lee   +2 more
wiley   +1 more source

Cavity Microelectrode Arrays for Electrical Recordings From Neurons

Advanced Electronic Materials, EarlyView.
Microelectrode arrays (MEAs) are used to study electrophysiological activity. However, their signals are small with high noise. By adding a 100‐nanometer‐high cavity above the electrode, which reduces impedance without affecting resolution, we improve signal quality.
Johannes Lewen, Bernhard Wolfrum, Andreas Offenhäusser   +2 more
wiley   +1 more source

The Relation Between Managed Care Market Share and the Treatment of Elderly Fee-For-Service Patients with Myocardial Infarction [PDF]

Managed care may affect medical treatments for non-managed-care patients if it alters local market structure or physician behavior. We investigate whether higher levels of overall managed care market share are associated with greater use of recommended ...
Laurence C. Baker, Mark McClellan, Craig Frances, Paul A. Heidenreich   +3 more
core  

Characteristics of Anal Fistula Cancer in Patients Who Underwent Surgery: A Nationwide Observational Study Using Diagnosis Procedure Combination Data

Annals of Gastroenterological Surgery, EarlyView.
The characteristics of patients with anal fistula cancer included a higher proportion of men, younger age, more smokers, and tumor‐related characteristics, including more advanced local progression. Surgical characteristics included a lower rate of minimally invasive surgery, a higher proportion of total pelvic exenterations, and longer postoperative ...
Nobuaki Hoshino, Hiromitsu Kinoshita, Kazutaka Obama, Kiyohide Fushimi, Susumu Kunisawa, Yuichi Imanaka   +5 more
wiley   +1 more source

Efficacy of zofenopril in combination with amlodipine in patients with acute myocardial infarction: a pooled individual patient data analysis of four randomized, double-blind, controlled, prospective studies.

, 2018
Objective: In the four SMILE (Survival of Myocardial Infarction Long-Term Evaluation) studies, early administration of zofenopril in acute myocardial infarction (AMI) showed beneficial effects as compared to placebo and other angiotensin converting ...
Borghi C, Omboni S, Degli Esposti D, Bacchelli S, Ambrosioni E, SMILE (Survival of Myocardial Infarction Long-Term Evaluation) Working Project, Reggiardo G   +6 more
core   +1 more source

Relationship Between Hospital Volume and Outcomes of Minimally Invasive Esophagectomy for Esophageal Cancer: Analysis of the National Clinical Database in Japan

Annals of Gastroenterological Surgery, EarlyView.
According to multivariable analysis conducted using a hierarchical logistic regression model, using VHH as the reference group, the odds ratios for mortality by hospital volume category were as follows: VLH, 2.70 (p < 0.0001); LH, 1.72 (p = 0.052); MH, 1.70 (p = 0.034); and HH, 1.43 (p = 0.173).
Soji Ozawa, Hiraku Kumamaru, Yuko Kitagawa, Kazuo Koyanagi, Junya Oguma, Harushi Udagawa, Hiroaki Miyata, Yasushi Toh, Hisahiro Matsubara   +8 more
wiley   +1 more source

Iron Deposition following Chronic Myocardial Infarction as a Substrate for Cardiac Electrical Anomalies: Initial Findings in a Canine Model

, 2013
Purpose: Iron deposition has been shown to occur following myocardial infarction (MI). We investigated whether such focal iron deposition within chronic MI lead to electrical anomalies. Methods: Two groups of dogs (ex-vivo (n = 12) and in-vivo (n = 10))
Cokic Ivan, Stewart Brian, Tang, Richard, Cokic, Ivan, Wang Xunzhang, Allen M Amorn, Thajudeen, Anees, Bennett, Nathan, Richard L Q Tang, Nathan Bennett (459351), Amorn, Allen M., Sotirios A Tsaftaris, Bennett Nathan, Harlev Doron, Thajudeen Anees, Tsaftaris Sotirios A., Chugh, Sumeet S., Brian Stewart, Harlev, Doron, Allen M. Amorn (459348), Sumeet S. Chugh (215629), Tsaftaris, Sotirios A., Shehata Michael, Xunzhang Wang, Rohan Dharmakumar (459355), Chugh Sumeet S., Dharmakumar Rohan, Doron Harlev, Hsin-Jung Yang, Yang, Hsin-Jung, Amorn Allen M., Brian Stewart (459350), Wang, Xunzhang, Avinash Kali, Enzhao Liu, Nathan Bennett, Avinash Kali (459342), Warren M. Jackman (459354), Michael Shehata, Richard L. Q. Tang (459345), Tang Richard L. Q., Hsin-Jung Yang (459344), Michael Shehata (459347), Warren M Jackman, Jackman Warren M., Liu Enzhao, Liu, Enzhao, Sotirios A. Tsaftaris (459353), Ivan Cokic (459341), Rohan Dharmakumar, Stewart, Brian, Sumeet S Chugh, Ivan Cokic, Anees Thajudeen, Enzhao Liu (459349), Yang Hsin-Jung, Dharmakumar, Rohan, Jackman, Warren M., Kali, Avinash, Doron Harlev (459352), Shehata, Michael, Anees Thajudeen (459346), Kali Avinash, Xunzhang Wang (459343)   +63 more
core   +1 more source

AI‐Assisted IoT‐Enabled ECG Monitoring: Integrating Foundational and Generative AI Tools for Sustainable Smart Healthcare—Recent Trends

AI &Innovation, EarlyView.
ABSTRACT The rapid evolution of the Internet of Things (IoT) has significantly advanced the field of electrocardiogram (ECG) monitoring, enabling real‐time, remote, and patient‐centric cardiac care. This paper presents a comprehensive survey of AI assisted IoT‐based ECG monitoring systems, focusing on the integration of emerging technologies such as ...
Amrita Choudhury, Kandarpa Kumar Sarma, Lachit Dutta   +2 more
wiley   +1 more source