Results 91 to 100 of about 1,979,548 (395)

Low-Attenuation Noncalcified Plaque on Coronary Computed Tomography Angiography Predicts Myocardial Infarction

Circulation, 2020
Supplemental Digital Content is available in the text. Background: The future risk of myocardial infarction is commonly assessed using cardiovascular risk scores, coronary artery calcium score, or coronary artery stenosis severity.
M. Williams, J. Kwieciński, M. Doris, P. McElhinney, Michelle S D'souza, S. Cadet, P. Adamson, A. Moss, S. Alam, A. Hunter, Anoop S. V. Shah, N. Mills, T. Pawade, Chengjia Wang, J. W. Weir McCall, Michael Bonnici-Mallia, C. Murrills, G. Roditi, E. V. van Beek, L. Shaw, E. Nicol, D. Berman, P. Slomka, D. Newby, M. Dweck, D. Dey   +25 more
semanticscholar   +1 more source

A Personalized, 3D Printed Polymeric Device for the Prevention of Post‐Myocardial Infarction Cardiac Remodeling

Advanced Healthcare Materials, EarlyView.
Myocardial infarction often leads to pathological remodelling and ventricular dilatation, key features of HFrEF. This study introduces a personalized, 3D‐printed cardiac restraint device (CARD) printed using rationally designed inks displaying the requested printability and mechanical properties.
Nicola Mansour, Daniel Cohn, Ishita Sarkar, Raja Alamore, Kareem Abd Rbo, Offer Amir, Dean Nachman   +6 more
wiley   +1 more source

Divergent roles of red cell arginase in humans and mice: RBC Arg1 KO mice show preserved systemic l-arginine bioavailability and infarct size in vivo

Redox Biology
In humans and other primates, red blood cells (RBCs) constitutively express high levels of liver-type arginase 1 (Arg1), which regulates systemic l-arginine and nitric oxide (NO) bioavailability, particularly under pathological conditions such as sickle ...
Sophia K. Heuser, Junjie Li, Zhixin Li, Anthea LoBue, Kyle Heard, Julia Hocks, Tatsiana Suvorava, Ron-Patrick Cadeddu, Corinna Strupp, Luke Dunaway, Zhengbing Zhuge, Stacy L. Gelhaus, André Heinen, Ulrich Germing, Martin Feelisch, Mattias Carlström, Brant Isakson, Malte Kelm, Jon O. Lundberg, Miriam M. Cortese-Krott   +19 more
doaj   +1 more source

Mitochondria in acute myocardial infarction and cardioprotection

EBioMedicine, 2020
Acute myocardial infarction (AMI) and the heart failure (HF) that often follows are among the leading causes of death and disability worldwide. As such, new treatments are needed to protect the myocardium against the damaging effects of the acute ...
C. Ramachandra, S. Hernandez-Resendiz, G. Crespo-Avilan, Ying-Hsi Lin, D. Hausenloy   +4 more
semanticscholar   +1 more source

Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction

Advanced Healthcare Materials, EarlyView.
Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang, Jingguo Qu, Tonghuan Xiao, Xinyang Han, Michael Tin‐Cheung Ying   +4 more
wiley   +1 more source

Is combined myocardial performance index and tricuspid annular plane systolic excursion a better predictive estimator than each of them alone in patients with inferior ST-elevation myocardial infarction?

Türk Kardiyoloji Derneği Arşivi, 2014
Objectives: We aimed to assess the combined estimator of left ventricular (LV) myocardial performance index (MPI) and tricuspid annular plane systolic excursion (TAPSE) as a pooled independent predictive factor for hospital mortality and one-year ...
Hamlet Grigori Hayrapetyan, Karlen Grigori Adamyan, Inna Arshavir Arakelyan   +2 more
doaj   +1 more source

New perspectives to repair a broken heart [PDF]

, 2009
The aim of cardiac cell therapy is to restore at least in part the functionality of the diseased or injured myocardium by the use of stem/ progenitor cells.
BARILE, Lucio, CHIMENTI, ISOTTA, DI CONSIGLIO, ALBERTO, FORTE, ELVIRA, FRATI, GIACOMO, GAETANI, ROBERTO, GIACOMELLO, Alessandro, IONTA, VITTORIA, MESSINA, ELISA, MIRALDI, Fabio   +9 more
core   +1 more source

Acute Myocardial Infarction in Young Individuals.

Mayo Clinic proceedings, 2020
Globally, cardiovascular disease remains a major cause of adverse outcomes in young individuals, unlike its decline in other age groups. This group is not well studied and has a unique risk profile with less traditional cardiovascular risk factors ...
R. Gulati, A. Behfar, J. Narula, A. Kanwar, A. Lerman, L. Cooper, Mandeep Singh   +6 more
semanticscholar   +1 more source

Extracellular Vesicles Modulation by an Adiponectin Receptor Agonist Provides Cardioprotection for Myocardial Ischemic Injury

Advanced Healthcare Materials, EarlyView.
This study demonstrates that ALY688, a drug mimicking the heart‐protective hormone adiponectin, reduces myocardial ischemia injury. ALY688 increases the production of extracellular vesicles, which carry protective cargo including adiponectin itself.
Jialing Tang, Wing Yan Chung, Serena M. Pulente, Yubin Lei, Khang Nguyen, Eddie Tam, Nadya M. Morrow, Ilka Lorenzen‐Schmidt, Fengxia Xiao, Augusto Zani, Dylan Burger, Hye Kyoung Sung, Erin E. Mulvihill, Gary Sweeney   +13 more
wiley   +1 more source

How to balance acute myocardial infarction and COVID-19: the protocols from Sichuan Provincial People’s Hospital

Intensive Care Medicine, 2020
Dear Editor, Acute myocardial infarction (AMI) is a cardiovascular emergency and requires an emergency diagnosis and treatment process. Unfortunately, the highly contagious COVID-19 pneumonia is obviously affecting the diagnosis and treatment of acute ...
Jie Zeng, Jianxin Huang, Lingai Pan
semanticscholar   +1 more source