Results 81 to 90 of about 644,429 (317)

Infusible Extracellular Matrix Biomaterial Enhances Cell‐Specific Pro‐Repair Responses Following Acute Myocardial Infarction

Advanced Healthcare Materials, EarlyView.
We measure the cell‐specific responses of administering infusible ECM (iECM) in acute myocardial infarction (MI) across multiple timepoints. Using single‐nucleus RNA sequencing and spatial transcriptomics, we measure macrophage activation, fibroblast remodeling, increased vascular development, lymphangiogenesis, cardioprotection, and neurogenesis ...
Joshua M. Mesfin, Alexander Chen, Quincy P. Lyons, Michael B. Nguyen, Maria L. Karkanitsa, Justin Yu, Van K. Ninh, Emily Gardner, Elyse G. Wong, Sriya N. Paleti, Julian Cheng, Benjamin D. Bridgelal, Kate E. Reimold, Selena Cao, Connor Uhre, Colin G. Luo, Zhenxing Fu, Kevin R. King, Karen L. Christman   +18 more
wiley   +1 more source

Long-term effects of autologous bone marrow stem cell treatment in acute myocardial infarction: factors that may influence outcomes

, 2012
AIMS: To investigate whether there are important sources of heterogeneity between the findings of different clinical trials which administer autologous stem cell treatment for acute myocardial infarction (AMI) and to evaluate what factors may influence ...
Anthony Mathur, Fisher Sheila A., Doree Carolyn, Doree, C, Mike J Clarke, Carolyn Doree (162145), Enca Martin-Rendon, Mathur Anthony, Clarke, MJ, Martin-Rendon Enca, Susan J Brunskill, Brunskill, Susan J., Susan J. Brunskill (162133), Watt, SM, Sheila A. Fisher (162124), Clifford, DM, Mike J. Clarke (162164), Watt Suzanne M., Carolyn Doree, Clifford, David M., Fisher, Sheila A., Brunskill, SJ, Suzanne M Watt, David M. Clifford (162115), Martin-Rendon, E, David M Clifford, Watt, Suzanne M., Brunskill Susan J., Clifford David M., Enca Martin-Rendon (162178), Suzanne M. Watt (162171), Fisher, SA, Doree, Caroyln, Mathur, Anthony, Clarke Mike J., Clarke, Michael, Anthony Mathur (162155), Sheila A Fisher, Martin-Rendon, Enca, Mathur, A   +39 more
core   +1 more source

The Myocardial Ischaemia National Audit Project (MINAP). [PDF]

, 2010
UNLABELLED: AIMS OF MINAP: To audit the quality of care of patients with acute coronary syndrome and provide a resource for academic research. QUALITY OF CARE INTERVENTIONS: Feedback to hospitals, ambulance services and cardiac networks regarding ...
Clive Weston, C. Weston, E. Herrett, Herrett, Emily, Fox, Keith, L. Smeeth, MINAP Academic Group, Walker, Lynne, ?, ?, Weston, Clive, null null, Smeeth, Liam, L. Walker   +12 more
core   +1 more source

Coaxially Electrospun Myocardial dECM‐ Based Nanofibrous Scaffolds Demonstrate Enhanced Cardiomyocyte Biocompatibility

Advanced Healthcare Materials, EarlyView.
Our coaxial electrospinning system is capable of incorporating decellularized myocardial extracellular matrix in a core‐sheath configuration, creating nanofibrous scaffolds. These scaffolds, in turn, support the maintenance of functional cardiomyocytes adhered to the surface of these bioactive scaffolds.
Dhanusha N. Rajapakse, Mahtab Khodadadi, Kiran M. Ali, Suh Hee Cook, Bryson T. Proctor, Tanya Upadhyay, Daxian Zha, Fatema Tuj Jahura, Marziyeh Boosaliki, Jessica M. Gluck   +9 more
wiley   +1 more source

Microvascular resistance predicts myocardial salvage and infarct characteristics in ST-elevation myocardial infarction [PDF]

, 2012
<b>Background:</b> The pathophysiology of myocardial injury and repair in patients with ST‐elevation myocardial infarction is incompletely understood. We investigated the relationships among culprit artery microvascular resistance, myocardial
Petrie, Mark C., Oldroyd, Keith G., Lindsay, M. Mitchell, Foster, John, McEntegart, Margaret, Tzemos, Nikolaos, Weale, Peter, McComb, Christie, Berry, Colin, Doolin, Orla, Payne, Alexander R., Hood, Stuart, Ford, Ian, Carrick, David   +13 more
core   +1 more source

Magnetic Micro‐ and Nanorobots for Precision Thrombolysis: Design Strategies and Translational Challenges

Advanced Robotics Research, EarlyView.
Micro‐ and nanorobots for targeted thrombolysis. This perspective elaborates on the clinical indication of blood clot disorders and current limitations for treatment. As a novel, alternative solution, micro‐ and nanorobots can be used to treat and break down thrombi.
Joshua M. Mesfin, Yimo Yan, Nikola Cesarovic, Simone Schuerle   +3 more
wiley   +1 more source

Constituent country inequalities in myocardial infarction incidence and case fatality in men and women in the United Kingdom, 1996-2005. [PDF]

, 2010
BACKGROUND: Understanding myocardial infarction (MI) incidence and case fatality trends across the four UK constituent countries is of importance following devolution of the government of health-care services.
E. Grundy, Davies, Alisha Ruth, Smeeth, Liam, D. Nitsch, Davies, AR, Nitsch, D, Nitsch, Dorothea, Smeeth, L, L. Smeeth, Grundy, Emily, A. R. Davies, Grundy, E   +11 more
core   +1 more source

In Vivo Microplastic Detection With Photoacoustic Imaging

Advanced Science, EarlyView.
ABSTRACT Microplastics are posing an escalating threat to both ecological systems and human health. Yet, current methods for investigating their bioaccumulation are highly invasive, requiring destructive analysis of ex vivo tissues via mass spectrometry, dye labelling, or Raman microspectroscopy.
Joseph C. Bear, Olumide Ogunlade, Jayvian Mavi, Emily J. Deniszczyc, Daolong Chen, Heeva Javaheri, Paul Beard, Mark F. Lythgoe, Daniel J. Stuckey, P. Stephen Patrick   +9 more
wiley   +1 more source

Gender differences in hospital mortality and use of percutaneous coronary intervention in acute myocardial infarction : microsimulation analysis of the 1999 nationwide french hospitals database. [PDF]

Background— Women with acute myocardial infarction have a higher hospital mortality rate than men. This difference has been ascribed to their older age, more frequent comorbidities, and less frequent use of revascularization.
Steg, Philippe Gabriel, Dormont, Brigitte, Milcent, Carine, Durand-Zaleski, Isabelle   +3 more
core  

PET Imaging of Cardiac Inflammation in Viral Myocarditis Using a DPP4‐Targeted Probe

Advanced Science, EarlyView.
This study describes a DPP4‐targeted PET probe for imaging myocardial inflammation by selectively targeting activated immune cells. Derived from the clinically approved small‐molecule inhibitor linagliptin, the probe demonstrates favorable biodistribution with specific cardiac uptake in myocarditis.
Wanhao Gao, Wenzhu Hu, Du Tang, Xinxin Liu, Kun Yu, Lixia Feng, Minyu Liao, Wang Lin, Wenqiang Zhu, Sanjay Rajagopalan, Xiaoli Lan, Jixin Zhong, Dao Wen Wang, Dawei Jiang, Xiaoquan Rao   +14 more
wiley   +1 more source