Results 121 to 130 of about 1,289,832 (353)

A review of the molecular mechanisms underlying the development and progression of cardiac remodeling [PDF]

, 2017
Pathological molecular mechanisms involved in myocardial remodeling contribute to alter the existing structure of the heart, leading to cardiac dysfunction.
Angelini, Francesco, Bordin, Antonella, Carrizzo, Albino, Chimenti, Isotta, DE FALCO, Elena, Forte, Maurizio, Frati, Giacomo, Nocella, Cristina, Pagano, Francesca, Palmerio, Silvia, Schiavon, Sonia, Schirone, Leonardo, Sciarretta, Sebastiano, Valenti, Valentina, Vecchione, Carmine, Yee, Derek   +15 more
core   +3 more sources

Cardiac Organoid Model Inspired Micro‐Robot Smart Patch to Treat Myocardial Infarction

Advanced Materials, EarlyView.
The heart organoid model exhibits the acidic microenvironment characteristic of myocardial infarction, which emerges as a pivotal force propelling the movement of micro‐robots. These micro‐robots, administered through microneedles, can penetrate deep into the tissue, effectively delivering therapeutic payloads to facilitate heart repair.
Fangfang Wang, Zilu Xu, Feiyang Zheng, Dongcheng Yang, Kaige Xu, Ming Ke, Xiao Zhou, Xiaohan Zhang, Ju Tan, Yong Liu, Yansha Hao, Malcolm Xing, Chuhong Zhu   +12 more
wiley   +1 more source

Three-dimension structure of ventricular myocardial fibers after myocardial infarction [PDF]

, 2010
Background To explore the pathological changes of three-dimension structure of ventricular myocardial fibers after anterior myocardial infarction in dog heart. Methods Fourteen acute anterior myocardial infarction models were made from healthy dogs (mean
C Gao, C Gao, CA Beltrami, Changqing Gao, E Braunwald, E Schwammenthal, F Torrent-Guasp, F Torrent-Guasp, F Torrent-Guasp, GD Buckberg, HM Thai, JE Møller, Libin Li, MA Pfeffer, P Gaudron, PL Temporelli, R Willenheimer, T Zhang, Weihua Ye, WH Ye, WH Ye   +20 more
core   +3 more sources

Long-term use of ticagrelor in patients with prior myocardial infarction.

New England Journal of Medicine, 2015
BACKGROUND The potential benefit of dual antiplatelet therapy beyond 1 year after a myocardial infarction has not been established. We investigated the efficacy and safety of ticagrelor, a P2Y12 receptor antagonist with established efficacy after an ...
Marc P. Bonaca, Deepak L. Bhatt, Marc Cohen, P. Steg, R. Storey, E. Jensen, G. Magnani, S. Bansilal, M. Fish, K. Im, O. Bengtsson, T. Oude Ophuis, A. Budaj, P. Théroux, M. Ruda, C. Hamm, S. Goto, J. Špinar, J. Nicolau, R. Kiss, S. Murphy, S. Wiviott, P. Held, E. Braunwald, M. Sabatine   +24 more
semanticscholar   +1 more source

Artificially Weaved Textile‐like Surface Micromachined Graphene‐Polymer Flexible Bioelectrodes

Advanced Materials Technologies, EarlyView.
This study reports on the engineering of microscale textured surfaces of SU‐8/PMMA polymer composites much like a “weft‐warp” pattern to resemble “artificially‐weaved” textiles. These microstructured surfaces enable conformal layering of functional reduced graphene oxide (rGO), all‐in‐all offering favorable features including remarkable self ...
Seba Nur Alhasan, S. Sajjad Mirbakht, Saygun Guler, Osman Sahin, Muhammad Umar, Burcu Arman Kuzubasoglu, Murat Kaya Yapici   +6 more
wiley   +1 more source

Cost‐effectiveness of second‐line therapies in adults with chronic immune thrombocytopenia

American Journal of Hematology, Volume 98, Issue 1, Page 122-130, January 2023., 2023
Abstract Major options for second‐line therapy in adults with chronic immune thrombocytopenia (ITP) include splenectomy, rituximab, and thrombopoietin receptor agonists (TRAs). The American Society of Hematology guidelines recommend rituximab over splenectomy, TRAs over rituximab, and splenectomy or TRAs while noting a lack of evidence on the cost ...
George Goshua, Pranay Sinha, Natalia Kunst, Lauren Pischel, Alfred Ian Lee, Adam Cuker   +5 more
wiley   +1 more source

The Biological Basis for Cardiac Repair After Myocardial Infarction: From Inflammation to Fibrosis.

Circulation Research, 2016
In adult mammals, massive sudden loss of cardiomyocytes after infarction overwhelms the limited regenerative capacity of the myocardium, resulting in the formation of a collagen-based scar.
S. Prabhu, N. Frangogiannis
semanticscholar   +1 more source

Mechanochemistry: Fundamental Principles and Applications

Advanced Science, EarlyView.
In this review, the physicochemical principles of mechanochemistry are first clarified. Based on this foundation, the research basis and cutting‐edge scientific achievements in four areas are introduced: solid‐state organic chemistry, polymers, interface science, and biomechanochemistry.
Liang Dong, Luofei Li, Huiyan Chen, Yi Cao, Hai Lei   +4 more
wiley   +1 more source

Red blood cell eNOS is cardioprotective in acute myocardial infarction

Redox Biology, 2022
Red blood cells (RBCs) were shown to transport and release nitric oxide (NO) bioactivity and carry an endothelial NO synthase (eNOS). However, the pathophysiological significance of RBC eNOS for cardioprotection in vivo is unknown.
Miriam M. Cortese-Krott, Tatsiana Suvorava, Francesca Leo, Sophia K. Heuser, Anthea LoBue, Junjie Li, Stefanie Becher, Rebekka Schneckmann, Tanu Srivrastava, Ralf Erkens, Georg Wolff, Joachim P. Schmitt, Maria Grandoch, Jon O. Lundberg, John Pernow, Brant E. Isakson, Eddie Weitzberg, Malte Kelm   +17 more
doaj  

Cascaded Framework for Automatic Evaluation of Myocardial Infarction from Delayed-Enhancement Cardiac MRI [PDF]

arXiv, 2020
Automatic evaluation of myocardium and pathology plays an important role in the quantitative analysis of patients suffering from myocardial infarction. In this paper, we present a cascaded convolutional neural network framework for myocardial infarction segmentation and classification in delayed-enhancement cardiac MRI.
arxiv