Results 131 to 140 of about 1,818,147 (330)

Correction: Left ventricular function and coronary microcirculation in patients with mild reduced ejection fraction after STEMI

open access: yesBMC Cardiovascular Disorders, 2022
Yuliang Ma   +9 more
doaj   +1 more source

Recent Advances in Laser‐Induced Phase Separation of PEDOT:PSS for Bioelectronics

open access: yesAdvanced Photonics Research, EarlyView.
This review explores the potential of laser‐induced phase separation of PEDOT:PSS for bioelectronic applications. It highlights the properties including enhanced electrical conductivity, wet stability, electrochemical stability, high pattern resolution, and biocompatibility.
Bei'er Zhu   +4 more
wiley   +1 more source

Cytokine Engineering Approaches for Regenerative Medicine

open access: yesAdvanced Therapeutics, EarlyView.
Engineered cytokines represent a powerful strategy to promote tissue repair and regeneration by precisely modulating immune responses. This review highlights recent advances in cytokine engineering, including strategies to enhance half‐life, improve tissue and cell targeting, and control receptor signaling.
Shiyi Li, Wenhao You, Mikaël M. Martino
wiley   +1 more source

ACUTE MYOCARDIAL INFARCTION IN ISFAHAN, IRAN: HOSPITALIZATION AND 28TH DAY CASE-FATALITY RATE

open access: yesARYA Atherosclerosis, 2010
   BACKGROUND: This study aimed to investigate 28-day case fatality rate due to acute myocardial infarction (MI) in Isfahan using a standardized surveillance system.
Nizal Sarrafzadegan   +4 more
doaj  

Engineered RGD‐Treg‐Exos Targeted Delivery of miR‐218‐5p to Activate Mitophagy and Attenuate Podocyte Injury in Diabetic Kidney Disease

open access: yesAdvanced Science, EarlyView.
Tregs‐Exos deliver miR‐218‐5p to increase mitophagy in podocytes by inhibiting the TNC/TLR4/SRC/FUNDC1 pathway. RGD‐Treg‐Exos, engineered to express RGD peptides on the membrane surface, bind to integrins on the surface of podocytes and effectively target podocytes for the delivery of miR‐218‐5p, which increases mitophagy and reduces apoptosis in ...
Zhaochen Guo   +11 more
wiley   +1 more source

Hypoglycemia Induces Diabetic Macrovascular Endothelial Dysfunction via Endothelial Cell PANoptosis, Macrophage Polarization, and VSMC Fibrosis

open access: yesAdvanced Science, EarlyView.
This study investigates hypoglycemia‐induced diabetic macrovascular endothelial dysfunction. It reveals that hypoglycemia triggers ZBP1‐dependent PANoptosis of endothelial cells, proinflammatory polarization of macrophages, and fibrosis of vascular smooth muscle cells (VSMCs) in diabetic mice.
Deyu Zuo   +10 more
wiley   +1 more source

A High-Throughput Biosensing Approach for Rapid Screening of Compounds Targeting the hNav1.1 Channel: Marine Toxins as a Case Study

open access: yesMarine Drugs
Voltage-gated sodium (Nav) channels play a crucial role in initiating and propagating action potentials throughout the heart, muscles and nervous systems, making them targets for a number of drugs and toxins.
Huijing Shen   +6 more
doaj   +1 more source

Microphysiological Uremia Model Reveals Biophysical Potentiators of Vascular Dysfunction

open access: yesAdvanced Science, EarlyView.
A microfluidic platform of engineered blood vessels is developed to study the role of mechanical forces in immune cell adhesion and extravasation in uremic microenvironments. Elevated pressure increases monocyte activity, with ICAM‐1 as a key driver. Matrix density influences monocyte phenotypes, but the uremic environment consistently promoted a pro ...
Mitesh Rathod   +9 more
wiley   +1 more source

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