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Myocardial Reperfusion Injury

open access: yesNew England Journal of Medicine, 2007
Lethal reperfusion injury is a paradoxical type of myocardial injury caused by the restoration of coronary blood flow after an ischemic episode. This review focuses on the mechanisms of the injury, on attempts to protect the heart against it, and on promising new approaches to cardioprotection during percutaneous coronary intervention.
Derek M Yellon, Derek J Hausenloy
exaly   +11 more sources

Perioperative Myocardial Injury

open access: yesTurkish Journal of Anaesthesiology and Reanimation, 2023
An increasing body of evidence suggests that a postoperative rise in cardiac troponin, even in the absence of other diagnostic criteria for myocardial infarction, is still associated with a range of postoperative complications including myocardial death and all-cause mortality.
Jack Brooker, Alparslan Turan
doaj   +3 more sources

Leucine zipper protein 1 prevents doxorubicin-induced cardiotoxicity in mice

open access: yesRedox Biology, 2023
Objective: Doxorubicin (DOX) is commonly used for chemotherapy; however, its clinical value is extremely dampened because of the fatal cardiotoxicity. Leucine zipper protein 1 (LUZP1) plays critical roles in cardiovascular development, and this study is ...
Di Fan   +15 more
doaj   +1 more source

Expression pattern and diagnostic value of ferroptosis-related genes in acute myocardial infarction

open access: yesFrontiers in Cardiovascular Medicine, 2022
BackgroundFerroptosis is a form of regulatory cell death (RCD) caused by iron-dependent lipid peroxidation. The role of ferroptosis in the process of acute myocardial infarction (AMI) is still unclear and requires further study.
Jiahe Wu   +19 more
doaj   +1 more source

Comprehensive Analysis of circRNA-miRNA-mRNA Regulatory Network and Novel Potential Biomarkers in Acute Myocardial Infarction

open access: yesFrontiers in Cardiovascular Medicine, 2022
BackgroundCircular RNA (circRNA) plays an important role in the regulation of gene expression and the occurrence of human diseases. However, studies on the role of circRNA in acute myocardial infarction (AMI) are limited.
Jiahe Wu   +19 more
doaj   +1 more source

Myocardial injury

open access: yesМЕДИЦИНА НЕВІДКЛАДНИХ СТАНІВ, 2020
В обзоре представлены сведения о клинических отличиях между типами инфаркта миокарда, изложенные в соответствии с Четвертым универсальным определением инфаркта миокарда. Показано центральное место тропонина как маркера повреждения сердечной мышцы в современной диагностике инфаркта миокарда, в частности важность контроля этого показателя в динамике ...
Yakovleva, L.M., Yakovleva, L.M.
  +5 more sources

Protein O-GlcNAcylation in multiple immune cells and its therapeutic potential

open access: yesFrontiers in Immunology, 2023
O-GlcNAcylation is a post-translational modification of proteins that involves the addition of O-GlcNAc to serine or threonine residues of nuclear or cytoplasmic proteins, catalyzed by O-GlcNAc transferase (OGT).
Huanhuan Cai   +10 more
doaj   +1 more source

Myocardial Injury after Stroke [PDF]

open access: yesJournal of Clinical Medicine, 2021
The cardiovascular system is markedly affected by stress after stroke. There is a complex interaction between the brain and heart, and the understanding of the mutual effects has increased in recent decades. Stroke is accompanied by pathological disturbances leading to autonomic dysfunction and systemic inflammation, which leads to changes in ...
Michal Mihalovic, Petr Tousek
openaire   +2 more sources

Association of Clinical and Immunological Characteristics With Disease Severity and Outcomes in 211 Patients With COVID-19 in Wuhan, China

open access: yesFrontiers in Cellular and Infection Microbiology, 2021
BackgroundCoronavirus disease 2019 (COVID-19) has posed a great threat to global public health. There remains an urgent need to address the clinical significance of laboratory finding changes in predicting disease progression in COVID-19 patients.
Man Wang   +11 more
doaj   +1 more source

Remote Ischemic Preconditioning Neither Improves Survival nor Reduces Myocardial or Kidney Injury in Patients Undergoing Transcatheter Aortic Valve Implantation (TAVI) [PDF]

open access: yes, 2020
BACKGROUND: Peri-interventional myocardial injury occurs frequently during transcatheter aortic valve implantation (TAVI). We assessed the effect of remote ischemic preconditioning (RIPC) on myocardial injury, acute kidney injury (AKIN) and 6-month ...
Flechsig, Mandy   +14 more
core   +1 more source

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