Results 1 to 10 of about 274,417 (262)

Leucine zipper protein 1 prevents doxorubicin-induced cardiotoxicity in mice

open access: yesRedox Biology, 2023
Objective: Doxorubicin (DOX) is commonly used for chemotherapy; however, its clinical value is extremely dampened because of the fatal cardiotoxicity. Leucine zipper protein 1 (LUZP1) plays critical roles in cardiovascular development, and this study is ...
Di Fan   +15 more
doaj   +1 more source

Expression pattern and diagnostic value of ferroptosis-related genes in acute myocardial infarction

open access: yesFrontiers in Cardiovascular Medicine, 2022
BackgroundFerroptosis is a form of regulatory cell death (RCD) caused by iron-dependent lipid peroxidation. The role of ferroptosis in the process of acute myocardial infarction (AMI) is still unclear and requires further study.
Jiahe Wu   +19 more
doaj   +1 more source

Comprehensive Analysis of circRNA-miRNA-mRNA Regulatory Network and Novel Potential Biomarkers in Acute Myocardial Infarction

open access: yesFrontiers in Cardiovascular Medicine, 2022
BackgroundCircular RNA (circRNA) plays an important role in the regulation of gene expression and the occurrence of human diseases. However, studies on the role of circRNA in acute myocardial infarction (AMI) are limited.
Jiahe Wu   +19 more
doaj   +1 more source

Protein O-GlcNAcylation in multiple immune cells and its therapeutic potential

open access: yesFrontiers in Immunology, 2023
O-GlcNAcylation is a post-translational modification of proteins that involves the addition of O-GlcNAc to serine or threonine residues of nuclear or cytoplasmic proteins, catalyzed by O-GlcNAc transferase (OGT).
Huanhuan Cai   +10 more
doaj   +1 more source

Association of Clinical and Immunological Characteristics With Disease Severity and Outcomes in 211 Patients With COVID-19 in Wuhan, China

open access: yesFrontiers in Cellular and Infection Microbiology, 2021
BackgroundCoronavirus disease 2019 (COVID-19) has posed a great threat to global public health. There remains an urgent need to address the clinical significance of laboratory finding changes in predicting disease progression in COVID-19 patients.
Man Wang   +11 more
doaj   +1 more source

Mapping and Ablation of Isolated Frequent Symptomatic Premature Atrial Contractions in Patients With Structurally Normal Heart

open access: yesFrontiers in Cardiovascular Medicine, 2022
BackgroundThe present study investigated the safety and efficacy of mapping and ablating isolated premature atrial contractions (PACs) in patients with a structurally normal heart, as well as whether the elimination of PACs by radiofrequency catheter ...
Bo He   +24 more
doaj   +1 more source

Direct cardiac reprogramming: Toward the era of multi-omics analysis

open access: yesCell Insight, 2022
Limited regenerative capacity of adult cardiomyocytes precludes heart repair and regeneration after cardiac injury. Direct cardiac reprograming that converts scar-forming cardiac fibroblasts (CFs) into functional induced-cardiomyocytes (iCMs) offers ...
Mengxin Liu   +3 more
doaj   +1 more source

Identification of ribosomal protein family as immune-cell-related biomarkers of NAFLD by bioinformatics and experimental analyses

open access: yesFrontiers in Endocrinology, 2023
BackgroundImmune cells play an integral role in the development and progression of non-alcoholic fatty liver disease (NAFLD). This study was to identify immune-cell-related biomarkers for the diagnosis and treatment of NAFLD.Methods and findingsFirst, we
Gerui Li, Hang Li, Ze Chen, Ze Chen
doaj   +1 more source

Atrioventricular accessory pathway unmasked by heart valve replacement

open access: yesAnnals of Noninvasive Electrocardiology, 2022
A 50‐year‐old male patient with a history of severe valvular regurgitation underwent mitral and aortic valve replacement surgery 3 months ago. Preoperative 12‐lead electrocardiogram presented atrial flutter (AFL) and atrial fibrillation.
Yanli Long, Yi Li, Zhibing Lu
doaj   +1 more source

Myocardial injury is a risk factor for 6-week mortality in liver cirrhosis associated esophagogastric variceal bleeding

open access: yesScientific Reports, 2023
This study sought to investigate risk factors for 6-week mortality of patients with decompensated liver cirrhosis associated esophagogastric variceal bleeding (EGVB) and clinical characteristics of myocardial injury in cirrhotic patients with EGVB.
Bihan Liu   +5 more
doaj   +1 more source

Home - About - Disclaimer - Privacy