Results 101 to 110 of about 3,593 (184)

Preoperative activation of the renineangiotensin system and myocardial injury in noncardiac surgery: exploratory mechanistic analysis of the SPACE randomised controlled trial [PDF]

Background Hypertension therapy in older adults is often suboptimal, in part because of inadequate suppression of the renin–angiotensin–aldosterone system (RAAS).
Ackland, G
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Effect of Remote Ischemic Preconditioning on Myocardial Injury in Noncardiac Surgery: the PRINCE Randomized Clinical Trial

Background: Major noncardiac surgery carries high rates of postoperative myocardial injury and other complications. Remote ischemic preconditioning (RIPC) was reported to decrease these complications.
Greco, Massimiliano, Russo, Andrea, Cherednichenko, Andrey, Meroi, Francesco, Bosso, Stefano, Rana, Nerlep, Livi, Francesca, Covello, Remo Daniel, Donadello, Katia, Schiavoni, Lorenzo, Wang, Lini, Sansone, Pasquale, Roasio, Agostino, Fresilli, Stefano, Yavorovskiy, Andrey, Lombardi, Gaetano, Konkayev, Aidos, Bellomo, Rinaldo, Subbotin, Valerii, Bove, Tiziana, Šitum, Ivan, Belletti, Alessandro, Kabibulatov, Aituar, Guarracino, Fabio, Momesso, Elena, Pruna, Alessandro, Oliva, Federico Mattia, Beretta, Luigi, D'Amico, Filippo, Marmiere, Marilena, Pieri, Marina, Ryzhkov, Pavel, Turi, Stefano, Ti, Lian Kah, Brusasco, Claudia, Monaco, Fabrizio, Corradi, Francesco, Labanca, Rosa, Subbotin, Valery, Micali, Marco, Vietri, Simone, Monti, Giacomo, Lei, Chong, Berikashvili, Levan, Giardina, Giuseppe, Lembo, Rosalba, Fresta, Giuseppe, Kadantseva, Kristina, Landoni, Giovanni, Cecconi, Maurizio, Likhvantsev, Valery, Zangrillo, Alberto, Smirnova, Anastasia, Efremov, Sergey, Mantilla-Gutierrez, Hugo   +54 more
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Associations of Intraoperative Radial Arterial Systolic, Diastolic, Mean, and Pulse Pressures with Myocardial and Acute Kidney Injury after Noncardiac Surgery: A Retrospective Cohort Analysis

, 2020
BACKGROUND: Arterial pressure is a complex signal that can be characterized by systolic, mean, and diastolic components, along with pulse pressure (difference between systolic and diastolic pressures).
Turan, Alparslan, Ahuja, Sanchit, Khanna, Ashish K, Yang, Dongsheng, Ruetzler, Kurt, Mascha, Edward J, Maheshwari, Kamal, Cohen, Barak, Sessler, Daniel I   +8 more
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An Educational Intervention on the Role of Perioperative Troponin Monitoring in Adult Patients Undergoing Noncardiac Surgery

, 2021
Background: Myocardial injury after noncardiac surgery is considered a common perioperative complication associated with increased morbidity and mortality following surgery.
Plancarte, Araceli, Brady, Daniel, Valdes, Jorge   +2 more
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Study of the effect of Remote Ischaemic Preconditioning (RIPC) on the early and late phase of hepatic ischaemia reperfusion injury and the role of haemoxygenase in RIPC.

, 2010
Reperfusion following ischaemia results in endothelial and parenchymal injury through a complex cascade of events. This often occurs in human liver transplantation as well as with major liver resections and is referred to as Ischaemia Reperfusion ...
Tapuria, N.
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Association Between Myocardial Injury and Cardiovascular Outcomes of Orthopaedic Surgery

, 2020
BACKGROUND: Myocardial injury after noncardiac surgery (MINS) is common and of prognostic importance. Little is known about MINS in orthopaedic surgery.
Heels-Ansdell, Dianne, Devereaux, P.J., Villar, Juan Carlos, Garutti, R. Ignacio, McQueen, Matthew J., Malaga, German, Winemaker, Mitchell, Carlos Villar, Juan, Wang, Chew Yin, Le Manach, Yannick, Borges, Flavia, Heels-Ansdell, Diane, De Beer, Justin, VanHelder, Tomas, Thabane, Lehana, Leuwer, Martin, Biccard, Bruce M., Cruz, Patricia, Jacka, Michael J., Aguilera, Xavier, Garutti, Ignacio, Chan, Matthew T.V., Thomas, Sabu, Botto, Fernando, Sessler, Daniel I., Kurz, Andrea, Garg, Amit X., Nagele, Peter, Abraham, Valsa, Berwanger, Otavio, Srinathan, Sadeesh, Lamas, Claudia, Jacka, Michael, Pettit, Shirley, Rodseth, Reitze N., Szczeklik, Wojciech, Buse, Giovanna Lurati, Rubery, Paul, Shatin, NT, Yusuf, Salim, Avram, Victoria, Adili, Anthony, Walsh, Michael, Bosch, Jackie, Sigamani, Alben, Guyatt, Gordon, Mrkobrada, Marko, Pearse, Rupert M., Wang, C.Y., Alonso-Coello, Pablo, Thorlund, Kristian, Urrútia Cuchí, Gerard, Chow, Clara K., Bhandari, Mohit, Polanczyk, Carisi A., Chow, Clara, Tiboni, Maria   +56 more
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Prevention, Epidemiology, and Prognosis of Perioperative ­Myocardial Injury

, 2016
Annually over 200 million adults undergo noncardiac surgery worldwide. Myocardial ischaemia is a frequent cause of perioperative cardiac morbidity and mortality.
Philip Devereaux, Erin Morley, Erin Sloan   +2 more
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The PRINCE trial of remote ischaemic preconditioning in noncardiac surgery to reduce myocardial injury: sign o' the times.

The remote ischemic PReconditioning In Non-Cardiac surgEry (PRINCE) trial was a multinational, double-blind trial in which 1213 patients undergoing noncardiac surgical procedures were randomly assigned to receive remote ischaemic preconditioning (RIPC ...
Ackland, GL, Pinto, BB
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Design of a Randomized Placebo-Controlled Trial to Assess Dabigatran and Omeprazole in Patients with Myocardial Injury after Noncardiac Surgery (MANAGE)

, 2018
BACKGROUND: Worldwide approximately 200 million adults undergo major surgery annually, of whom 8 million are estimated to suffer a myocardial injury after noncardiac surgery (MINS).
Devereaux, P.J., Franzosi, Maria Grazia, Vincent, Jessica, Villar, Juan Carlos, Reitze Rodseth, Villa, Juan Carlos, Connolly, Stuart J., Sessler, Daniel I, Gordon Guyatt, Juan Carlos Villar, John Neary, Bangdiwala, Shrikant I., Miriam de Nadal, Tandon, Vikas, Shrikant I. Bangdiwala, Clive Kearon, Emmanuelle Duceppe, Denis Xavier, Magloire, Patrick, Daniel I. Sessler, Biccard, Bruce M., Bangdiwala, Shrikant I, Navneet K. Chaudhry, Meyhoff, Christian S., Rodseth, Reitze, Popova, Ekaterine, Jessica Vincent, Otavio Berwanger, Vikas Tandon, Botto, Fernando, Sessler, Daniel I., de Nadal, Miriam, Srinathan, Sadeesh K, Neary, John, Salim Yusuf, Devereaux, P J, Maria Grazia Franzosi, Eikelboom, John W, Berwanger, Otavio, Srinathan, Sadeesh K., Rao, Mangala, Pettit, Shirley, Duceppe, Emmanuelle, Shirley Pettit, Sadeesh K. Srinathan, Joel Parlow, Parlow, Joel, Szczeklik, Wojciech, Sharma, Mukul, Yusuf, Salim, Connolly, Stuart J, Wojciech Szczeklik, Patrick Magloire, Chaudhry, Navneet K., Mukul Sharma, Xavier, Denis, Bruce M. Biccard, Stuart J. Connolly, Guyatt, Gordon, Chaudhry, Navneet K, Kearon, Clive, Bongani Mayosi, Mangala Rao, Mayosi, Bongani, Meyhoff, Christian S, P.J. Devereaux, Christian S. Meyhoff, Guyatt, Gordon H., John W. Eikelboom, Fernando Botto, Biccard, Bruce M, Ekaterine Popova, Eikelboom, John W.   +72 more
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Myocardial injury after non-cardiac surgery: a new clinical entity

, 2014
Objectives: The objective was to determine the diagnostic criteria of a prognostically important troponin elevation following non-cardiac surgery. Background: A postoperative troponin leak following non-cardiac surgery is independently associated with 30-
Biccard, B M
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