Results 151 to 160 of about 176,278 (292)

Gout and NLRP3 Inflammasome Biology

Arthritis &Rheumatology, EarlyView.
This review describes the three broad stages of acute inflammation in the context of gout: initiation, leucocyte mobilization, and self‐resolution. A typical case of a gout flare is presented. The role of the NLRP3 inflammasome in acute monosodium urate crystal–induced inflammation is reviewed in detail.
Raewyn Poulsen, Nicola Dalbeth
wiley   +1 more source

Effect of Coronary Vasodilator Drugs on Retrograde Flow in Areas of Chronic Myocardial Ischemia

, 1964
Wadie M. Fam, Maurice McGregor
openalex   +1 more source

Left Ventricular Pressure-Volume Alterations and Regional Disorders of Contraction During Myocardial Ischemia Induced by Atrial Pacing [PDF]

, 1970
Edward M. Dwyer
openalex   +1 more source

Deletion of Cardiac miR-17-92 Cluster Increases Ischemia/ Reperfusion Injury via PTEN Upregulation [PDF]

, 2017
The miR-17- 92 cluster is necessary for cell proliferation and development of the cardiovascular system. Deletion of this cluster leads to death in neonatal mice.
Prakash, Meeta B
core   +1 more source

Senkyunolide I Improves Septicemia‐Induced Brain Dysfunction via Regulating Nrf2 and Astrocyte Activity.

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Senkyunolide I (Sen I) has a protective effect on the blood–brain barrier (BBB) in rats with sepsis‐associated encephalopathy (SAE). This study investigated whether Sen I regulates Nrf2 to ameliorate sepsis‐induced brain dysfunction (SIBD). Sixty rats were randomly assigned into Sham group, SAE group (Model group), SAE + Sen I group (72 mg/kg,
Haohao Cao, Tao Liu, Meixia Xu
wiley   +1 more source

Mitochondria-derived methylmalonic acid, a surrogate biomarker of mitochondrial dysfunction and oxidative stress, predicts all-cause and cardiovascular mortality in the general population

Redox Biology, 2020
Background: Inherited methylmalonic acidemia is characterized by mitochondrial dysfunction, oxidative stress, and damage of mitochondria-rich organs in children. It is unclear whether methylmalonic acid (MMA) is related to poor prognosis in adults.
Shanjie Wang, Yige Liu, Jinxin Liu, Wei Tian, Xiaoyuan Zhang, Hengxuan Cai, Shaohong Fang, Bo Yu   +7 more
doaj  

The "border zone" in myocardial ischemia. An electrophysiological, metabolic, and histochemical correlation in the pig heart. [PDF]

, 1979
M J Janse, Juan Cinca, H Moréna, J W Fiolet, A G Kléber, G. P. de Vries, A Becker, D Durrer   +7 more
openalex   +1 more source

Remote preconditioning by aortic constriction: affords cardioprotection as classical or other remote ischemic preconditioning? Role of iNOS [PDF]

, 2011
Dose remote preconditioning by aortic constriction (RPAC) affords cardioprotection similar to classical or other remote ischemic preconditioning stimulus?
Akash Sharma, Arshee Munajjam, Ashish Sharma, Ashish Tiwari, Ashok Sharma, B.P. Srinivasan, Bhawna Vaishnav, Divya Sharma, Kunal Kishore, Richa Sharma, Rita Kumari, Shyam Agarwal   +11 more
core   +1 more source

Management of hypotension in dihydropyridine calcium channel blocker overdose: The role of high‐dose insulin therapy

British Journal of Clinical Pharmacology, EarlyView.
Aims Amlodipine poisoning is a leading cause of cardiovascular medication‐related deaths, commonly managed with high‐dose insulin (HDI) therapy. However, HDI is a vasodilator that is counterproductive in managing vasoplegia. We aim to study HDI therapy in patients with hypotension following dihydropyridine calcium channel antagonist (CCA) overdose ...
Betty S. H. Chan, Katherine Z. Isoardi, Darren M. Roberts, Ong Sook Har   +3 more
wiley   +1 more source

EFFECT OF MYOCARDIAL ISCHEMIA AT VARYING TEMPERATURES ON LEFT VENTRICULAR FUNCTION AND TISSUE OXYGEN TENSION

, 1961
Jack J. Greenberg, L. Henry Edmunds
openalex   +1 more source