Results 11 to 20 of about 229,436 (314)

Hypertension and Myocardial Ischemia

Medical Clinics of North America, 2009
Detailed studies over the past 30 years have built up an impressive evidence base for the presence of myocardial ischemia in patients who have hypertension. This relationship ranges from the obvious association with obstructive coronary artery disease to mechanisms related to hemodynamic, microcirculatory, and neuroendocrine abnormalities. All of these
Murphy, BP, Stanton, T, Dunn, FG
openaire   +6 more sources

Allosteric inhibition of cobalt binding to albumin by fatty acids : implications for the detection of myocardial ischemia [PDF]

, 2012
The biomarker "ischemia-modified albumin" (IMA), measured by the albumin-cobalt-binding assay (ACB assay), is the only FDA-approved biomarker for early diagnosis of myocardial ischemia.
Peter J. Sadler, Sadler, P. J., Sadler, Peter J., Claudia A. Blindauer, Teresa J. T. Pinheiro, Stewart, Alan J., Blindauer, Claudia A., Pinheiro, Teresa J. T., Jin Lu, Lu, Jin, Alan J. Stewart   +10 more
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NOX1 promotes myocardial fibrosis and cardiac dysfunction via activating the TLR2/NF-κB pathway in diabetic cardiomyopathy

Frontiers in Pharmacology, 2022
Diabetic cardiomyopathy (DCM) is a prevalent complication in patients with diabetes, resulting in high morbidity and mortality. However, the molecular mechanisms of diabetic cardiomyopathy have yet to be fully elucidated. In this study, we investigated a
Dandan Zhang, Dandan Zhang, Yilan Li, Yilan Li, Weijie Wang, Weijie Wang, Xueyan Lang, Xueyan Lang, Yanxiu Zhang, Yanxiu Zhang, Qianqian Zhao, Qianqian Zhao, Jingru Yan, Jingru Yan, Yao Zhang, Yao Zhang   +15 more
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A novel swine model for evaluation of dyslipidemia and atherosclerosis induced by human CETP overexpression

Lipids in Health and Disease, 2017
Background The mechanism of cholesteryl ester transfer protein (CETP) in lipid metabolism is still unclear. Furthermore, the relationship of CETP and atherosclerosis (AS) has been controversial. As pigs are a good model for both lipid and AS research, we
Tao Chen, Meng Sun, Jia-Qiang Wang, Jin-Jin Cui, Zhong-Hua Liu, Bo Yu   +5 more
doaj   +1 more source

Ferroptosis: A Potential Target in Cardiovascular Disease

Frontiers in Cell and Developmental Biology, 2022
Ferroptosis is a new form of regulatory cell death characterized by iron-dependent and intracellular lipid peroxidation. Ferroptosis can be divided into two stages.
Yanlong Leng, Yanlong Leng, Xing Luo, Xing Luo, Jiaying Yu, Jiaying Yu, Haibo Jia, Haibo Jia, Bo Yu, Bo Yu   +9 more
doaj   +1 more source

Protecting the ischemic heart : pharmacological protection against myocardial ischemia in rats in vivo and in vitro [PDF]

, 2004
Today in Switzerland approximately 40% of all deaths are due to cardiovascular diseases. More than half of these are due to ischemic heart disease. Among the fatal consequences of ischemic heart disease are life-threatening arrhythmias and myocardial ...
Butz, Silvia
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Q50, an Iron-Chelating and Zinc-Complexing Agent, Improves Cardiac Function in Rat Models of Ischemia/Reperfusion-Induced Myocardial Injury [PDF]

, 2013
Background: Reperfusion of ischemic myocardium may contribute to substantial cardiac tissue damage, but the addition of iron chelators, zinc or zinc complexes has been shown to prevent heart from reperfusion injury.
Faragó, Nóra, Hirschberg Kristóf, Korkmaz S, Merkely Béla Péter, Radovits, Tamás, Hirschberg, Kristóf, Barnucz E, Karck Matthias, Szabó Gábor, Fábián Gabriella, Gyuris Márió, Puskás László G., Loganathan Sivakkanan, Radovits Tamás, Weymann Alexander, Szabó, Csaba, Fábián, Gabriella, Loganathan, Sivakkanan, Karck, Matthias, Merkely, Béla, Kanizsai Iván, Faragó Nóra, Hegedűs Péter, Korkmaz, Sevil, Li Shiliang, Hegedűs, Péter, Gyuris, Márió, Szabó Csaba, Zubarevich Alina, Li, Shiliang, Puskás, László G., Korkmaz Sevil, Ózsvári, Béla, Zubarevich, Alina, Weymann, Alexander, Li S, Merkely Béla, Barnucz, Enikő, Puskás László, Kanizsai, Iván, Szabó, Gábor, Barnucz Enikő, Loganathan S, Ózsvári Béla   +43 more
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Omentin-1 effects on mesenchymal stem cells: proliferation, apoptosis, and angiogenesis in vitro

Stem Cell Research & Therapy, 2017
Background Mesenchymal stem cells (MSCs) are emerging as an extremely promising therapeutic agent for tissue repair. However, limitations exist such as the low numbers of MSCs obtained from donors, and the poor survival and function of donor cells ...
Li Yin, Dan Huang, Xinxin Liu, Yongshun Wang, Jingjin Liu, Fang Liu, Bo Yu   +6 more
doaj   +1 more source

Focal Geometry and Characteristics of Erosion-Prone Coronary Plaques in vivo Angiography and Optical Coherence Tomography Study

Frontiers in Cardiovascular Medicine, 2021
Objective: This study compared focal geometry and characteristics of culprit plaque erosion (PE) vs. non-culprit plaques in ST-segment elevated myocardial infarction (STEMI) patients in whom optical coherence tomography (OCT) identified PE as the cause ...
Muhua Cao, Muhua Cao, Tianyu Wu, Tianyu Wu, Jiawei Zhao, Jiawei Zhao, Zhuo Du, Zhuo Du, Zhuozhong Wang, Zhuozhong Wang, Lulu Li, Lulu Li, Guo Wei, Guo Wei, Jinwei Tian, Jinwei Tian, Haibo Jia, Haibo Jia, Gary S. Mintz, Bo Yu, Bo Yu   +20 more
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Intravenous sphingosylphosphorylcholine protects ischemic and postischemic myocardial tissue in a mouse model of myocardial ischemia/reperfusion injury [PDF]

, 2010
HDL, through sphingosine-1-phosphate (S1P), exerts direct cardioprotective effects on ischemic myocardium. It remains unclear whether other HDL-associated sphingophospholipids have similar effects.
Bodo Levkau, Levkau, Bodo, Herrgott, Ilka, Johanning, Kai, Echtermeyer, Frank, Chun, Jerold, Hildebrand, Reinhard, Ilka Herrgott, Gregor Theilmeier, Christine Herzog, Winterhalter, Michael, Frank Ulrich Müller, Schmitz, Martina, Müller, Frank Ulrich, Jan Mersmann, Michael Winterhalter, Reinhard Hildebrand, Martina Schmitz, Herzog, Christine, Frank Echtermeyer, Jerold Chun, Theilmeier, Gregor, Mersmann, Jan, Larmann, Jan, Jan Larmann, Kai Johanning   +25 more
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