Results 21 to 30 of about 329,173 (304)
Heat Shock Protein 70 Protects the Heart from Ischemia/Reperfusion Injury through Inhibition of p38 MAPK Signaling. [PDF]
, 2020 BackgroundHeat shock protein 70 (Hsp70) has been shown to exert cardioprotection. Intracellular calcium ([Ca2+]i) overload induced by p38 mitogen-activated protein kinase (p38 MAPK) activation contributes to cardiac ischemia/reperfusion (I/R) injury ...
Chen, Qing-Cai +10 more
core +1 more source
Reviews in Cardiovascular Medicine, 2021 The relationship between the in-stent neoatherosclerosis (ISNA) formation and the plaque’s characteristic changes in the non-culprit lesion is unclear.
Lei Xing +10 more
doaj +1 more source
Frontiers in Pharmacology, 2022 Diabetic cardiomyopathy (DCM) is a prevalent complication in patients with diabetes, resulting in high morbidity and mortality. However, the molecular mechanisms of diabetic cardiomyopathy have yet to be fully elucidated. In this study, we investigated a
Dandan Zhang +15 more
doaj +1 more source
Prevalence of anginal symptoms and myocardial ischemia and their effect on clinical outcomes in outpatients with stable coronary artery disease: data from the international observational CLARIFY registry [PDF]
, 2014 Importance: In the era of widespread revascularization and effective antianginals, the prevalence and prognostic effect of anginal symptoms and myocardial ischemia among patients with stable coronary artery disease (CAD) are unknown.<p></p>
Al-Zaibag, Muayed +11 more
core +1 more source
BMC Cardiovascular Disorders, 2022 Background Calcified plaque is thought to adversely impact outcomes after percutaneous coronary intervention (PCI). This study sought to evaluate the impact of nodular calcification in patients with acute coronary syndrome treated with primary ...
Abigail Demuyakor +17 more
doaj +1 more source
Transient limb ischemia induces remote ischemic preconditioning in vivo [PDF]
, 2002 Background-Ischemic preconditioning reduces local tissue injury caused by subsequent ischemia-reperfusion (IR), but may also have a salutary effect on IR injury of tissues remote from those undergoing preconditioning.
Hoschtitzky, JA +9 more
core +1 more source
Lipids in Health and Disease, 2017 Background The mechanism of cholesteryl ester transfer protein (CETP) in lipid metabolism is still unclear. Furthermore, the relationship of CETP and atherosclerosis (AS) has been controversial. As pigs are a good model for both lipid and AS research, we
Tao Chen +5 more
doaj +1 more source
ACE-inhibition prevents postischemic coronary leukocyte adhesion and leukocyte-dependent reperfusion injury [PDF]
, 1997 Objective: Polymorphonuclear leukocytes (PMN), retained in the microvascular bed, can contribute to postischemic myocardial reperfusion injury. Since a beneficial effect of ACE-inhibition on reperfusion injury has been reported, we investigated the ...
Becker, Bernhard F. +6 more
core +1 more source
Omentin-1 effects on mesenchymal stem cells: proliferation, apoptosis, and angiogenesis in vitro
Stem Cell Research & Therapy, 2017 Background Mesenchymal stem cells (MSCs) are emerging as an extremely promising therapeutic agent for tissue repair. However, limitations exist such as the low numbers of MSCs obtained from donors, and the poor survival and function of donor cells ...
Li Yin +6 more
doaj +1 more source
Ferroptosis: A Potential Target in Cardiovascular Disease
Frontiers in Cell and Developmental Biology, 2022 Ferroptosis is a new form of regulatory cell death characterized by iron-dependent and intracellular lipid peroxidation. Ferroptosis can be divided into two stages.
Yanlong Leng +9 more
doaj +1 more source