Results 41 to 50 of about 1,197,684 (320)

Persistent Cigarette Smoking Attenuates Plaque Stabilization in Response to Lipid-Lowering Therapy: A Serial Optical Coherence Tomography Study

open access: yesFrontiers in Cardiovascular Medicine, 2021
Objective: This study aimed to investigate the effect of smoking on morphological changes in non-culprit plaques in acute coronary syndrome (ACS) patients at 1 year after percutaneous coronary intervention (PCI), using optical coherence tomography (OCT ...
Xiling Zhang   +9 more
doaj   +1 more source

Mitochondrial Membrane Permeability Inhibitors in Acute Myocardial Infarction Still Awaiting Translation [PDF]

open access: yes, 2016
Despite therapeutic advances, acute myocardial infarction (AMI) remains a leading cause of morbidity and mortality worldwide. One potential limitation of the current treatment paradigm is the lack of effective therapies to optimize reperfusion after ...
Abbate, Antonio   +3 more
core   +2 more sources

Cardiac oxidative stress and inflammatory cytokines response after myocardial infarction [PDF]

open access: yes, 2015
Oxidative stress in heart failure or during ischemia/reperfusion occurs as a result of the excessive generation or accumulation of free radicals or their oxidation products.
Cerretani D.   +6 more
core   +1 more source

Differential Expression and Bioinformatics Analysis of CircRNA in PDGF-BB-Induced Vascular Smooth Muscle Cells

open access: yesFrontiers in Genetics, 2020
Atherosclerosis is mediated by various factors and plays an important pathological foundation for cardiovascular and cerebrovascular diseases.
Jiangtian Tian   +17 more
doaj   +1 more source

The meaning of different forms of structural myocardial injury, immune response and timing of infarct necrosis and cardiac repair [PDF]

open access: yes, 2015
Although a decline in the all-cause and cardiac mortality rates following myocardial infarction (MI) during the past 3 decades has been reported, MI is a major cause of death and disability worldwide.
Bello, S   +5 more
core   +1 more source

Prognostic Role of High Sensitivity C-Reactive Protein in Patients With Acute Myocardial Infarction

open access: yesFrontiers in Cardiovascular Medicine, 2021
Background: High sensitivity CRP (hs-CRP) has attracted intense interest in risk assessment. We aimed to explore its prognostic value in patients with acute myocardial infarction (AMI).Methods and Results: We enrolled 4,504 consecutive AMI patients in ...
Xiaoyuan Zhang   +7 more
doaj   +1 more source

Myocardial ischemic effects on cardiac electro-mechanical activity [PDF]

open access: yesarXiv, 2021
In this work, we investigated the effect of varying strength of Hyperkalemia and Hypoxia, in human cardiac tissue with a local ischemic subregion, on the electrical and mechanical activity of healthy and ischemic zones of the cardiac muscle. The Monodomain model in a deforming domain is taken with the addition of mechanical feedback and stretch ...
arxiv  

The Effect of Blood Pressure Variability on Coronary Atherosclerosis Plaques

open access: yesFrontiers in Cardiovascular Medicine, 2022
Hypertension is one of the most important risk factors for coronary heart disease (CHD). The regulation of blood pressure plays a significant role in the development and prognosis of CHD.
Yue Liu   +7 more
doaj   +1 more source

Guidelines for experimental models of myocardial ischemia and infarction

open access: yesAmerican Journal of Physiology. Heart and Circulatory Physiology, 2018
Myocardial infarction is a prevalent major cardiovascular event that arises from myocardial ischemia with or without reperfusion, and basic and translational research is needed to better understand its underlying mechanisms and consequences for cardiac ...
M. Lindsey   +19 more
semanticscholar   +1 more source

ACE-inhibition prevents postischemic coronary leukocyte adhesion and leukocyte-dependent reperfusion injury [PDF]

open access: yes, 1997
Objective: Polymorphonuclear leukocytes (PMN), retained in the microvascular bed, can contribute to postischemic myocardial reperfusion injury. Since a beneficial effect of ACE-inhibition on reperfusion injury has been reported, we investigated the ...
Becker, Bernhard F.   +6 more
core   +1 more source

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