Results 71 to 80 of about 217,798 (269)

Reprogramming the Myocardial Infarction Conductive Microenvironment with Superconductive Ionic Patch for Cardiac Function Repair

Advanced Science, EarlyView.
A super‐conductive ionic patch reprograms the post‐infarction microenvironment by enabling stable ionic migration and electrical signal transmission within damaged myocardium. The patch rapidly adheres to cardiac tissue, enhances conduction velocity, suppresses excitation‐contraction decoupling, and promotes structural and functional cardiac repair in ...
Changyong Wang, Zhuang Zhang, Qi Yin, Changgeng Xu, Linlin Liang, Siwei Li, Yuwei Zhao, Chunlan Wang, Jin Zhou   +8 more
wiley   +1 more source

The association of collaterals with myocardial ischemia and viability in chronic total occlusions

, 2022
Luís Leite, G Campos, Rodolfo Silva, Elisabete Jorge, Manuel Oliveira‐Santos, Andreia Gomes, Lino Gonçalves, Miguel Castelo‐Branco, Antero Abrunhosa, Maria João Ferreira   +9 more
openalex   +2 more sources

Fluorinated Carnitine Derivatives as Tools to Visualise Carnitine Transport and Metabolism

Advanced Science, EarlyView.
Fluorinated carnitines, fluoromethyl carnitine (FMC) and [18F]fluoromethyl carnitine ([18F]FMC), are synthesised and established as powerful probes to interrogate carnitine biology. The multimodal detection facilitated by fluorine labelling, including 19F NMR, mass spectrometry, and positron emission tomography imaging, allowed for visualisation of ...
Richard S. Edwards, Ella‐May Hards, Sofia N. dos Santos, Hannah E. Greenwood, Madeleine E. George, Andrea Emanuelli, Muhammet Tanc, Thomas R. Eykyn, Timothy H. Witney   +8 more
wiley   +1 more source

Inhibiting Matrix Metalloproteinase by Cell-Based Gene Transfer Effectively Treats Acute and Chronic Ischemic Cardiomyopathy

Cell Transplantation, 2012
After a myocardial infarction (MI), an increase in the cardiac ratio of matrix metalloproteinases (MMPs) relative to their inhibitors (TIMPs) causes extracellular matrix modulation that leads to ventricular dilatation and congestive heart failure.
Hai Tian M.D., Ph.D., Ming-Li Huang, Kai-Yu Liu, Zhi-Bo Jia, Lu Sun, Shu-Lin Jiang, Wei Liu, Heather Y. Mcdonald Kinkaid, Jun Wu, Ren-Ke Li M.D., Ph.D.   +9 more
doaj   +1 more source

Prognostic impact of location and extent of vessel-related ischemia at myocardial perfusion scintigraphy in patients with or at risk for coronary artery disease [PDF]

, 2015
Francesco Nudi, Orazio Schillaci, G Neri, Annamaria Pinto, Enrica Procaccini, Maurizio Vetere, Giacomo Frati, Fabrizio Tomai, Giuseppe Biondi‐Zoccai   +8 more
openalex   +1 more source

Targeting Microglial CD49a Inhibits Neuroinflammation and Demonstrates Therapeutic Potential for Parkinson's Disease

Advanced Science, EarlyView.
This study shows that integrin receptor CD49a (Itga1 gene) is significantly upregulated in hyperactivated microglia and microglia‐specific knockdown of Itga1 rescues neuroinflammation and neurodegeneration in a chronic Parkinson's disease (PD) model by targeting PGAM5‐mediated mitochondrial dysfunction and NLRP3 activation. Targeted inhibition of CD49a
Huanpeng Lu, Yunmin Zhu, Xi Wang, Zelin Wu, Zijian Xu, Rongqing Chen, Yanwu Guo   +6 more
wiley   +1 more source

Clinical outcomes of monitored anesthesia care vs. general anesthesia in transfemoral transcatheter aortic valve implantation: a single-center retrospective study

Frontiers in Cardiovascular Medicine
BackgroundTranscatheter aortic valve implantation (TAVI) has become a preferred treatment for severe aortic stenosis in high-risk patients. In China, general anesthesia (GA) remains the standard; however, monitored anesthesia care (MAC) offers a less ...
Haoran Zhang, Haoran Zhang, Tao Chen, Tao Chen, Bo Yu, Bo Yu, Donghui Zhang, Donghui Zhang   +7 more
doaj   +1 more source

Buxu Tongyu Granule Alleviates Myocardial Ischemia by Activating Vascular Smooth Muscle Cell Soluble Guanylate Cyclase to Inhibit Abnormal Vasomotion

, 2023
Shuang Yang, Yixiu Zhao, Xiaoling Cheng, Tingting Zhan, Jiaying Tian, Xue Liu, Chunyue Ma, Zhiqi Wang, Lu-ying Jin, Qian Liu, Yanli Wang, Jian Huang, Jinhui Wang, Yan Zhang, Baofeng Yang   +14 more
openalex   +1 more source

Esketamine/Ketamine: Dual‐Action Mechanisms and Clinical Prospects beyond Anesthesia in Psychiatry, Immunology, and Oncology

Advanced Science, EarlyView.
Esketamine and ketamine are widely used for perioperative analgesia and anesthesia. Despite their established roles in analgesia, sedation, and anesthesia, as well as emerging antidepressant, anti‐tumor, and anti‐inflammatory effects, their clinical use is limited due to side effects and addiction potential.
Yinxin Wang, Jiangang Xu, Xinyu Zhou, Lu Che, Minghan Qiu, Yang Liu, Ming Gao, Zhen Yang   +7 more
wiley   +1 more source

Corrigendum: Higher serum phosphorus and calcium levels provide prognostic value in patients with acute myocardial infarction

Frontiers in Cardiovascular Medicine, 2022
Wei Cao, Wei Cao, Yilan Li, Yilan Li, Yao Wen, Shaohong Fang, Shaohong Fang, Bing Zhao, Bing Zhao, Xiaoyuan Zhang, Xiaoyuan Zhang, Yanxiu Zhang, Yanxiu Zhang, Xueyan Lang, Xueyan Lang, Bo Yu, Bo Yu, Yao Zhang, Yao Zhang   +18 more
doaj   +1 more source