Results 41 to 50 of about 101,760 (277)

Frequency of Myocardial Dysfunction in Neonatal Sepsis: A Single Center Experience [PDF]

Pediatric Sciences Journal
Background: Myocardial dysfunction is an association of neonatal sepsis that might occur without underlying cardiac structural defect (CSD). Aims of the work: To study frequency of myocardial dysfunction (MD) in sepsis in full term neonates without CSD.
Sara I. AboElnour, Al Kassem Al Gameel, Noha Metwally Hammad   +2 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Long‐term prognostic value of an index of myocardial performance in patients with myocardial infarction [PDF]

Clinical Cardiology, 2002
AbstractBackground: The Tei index of myocardial performance (IMP), which combines parameters of both systolic and diastolic ventricular function, is a useful prognostic factor in many clinical settings.Hypothesis: This study assessed the long‐term prognostic value of IMP in patients discharged from hospital after acute myocardial infarction (AMI ...
Piotr, Szymański, Joanna, Rezler, Sebastian, Stec, Andrzej, Budaj   +3 more
openaire   +2 more sources

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Effect of septoplasty on left ventricular myocardial performance in patients with nasal septum deviation

Brazilian Journal of Otorhinolaryngology, 2022
Introduction: Nasal septum deviation is the leading cause of upper airway obstruction. Chronic upper airway obstruction may cause myocardial injury due to chronic hypoxia. Effects of septoplasty on left venticular diastolic and sistolic functions are not
Hakan Kaya, Ercan Kurt, Mehtap Koparal, Hakan Tibilli, Yusuf Hosoglu, Safiye Kafadar, Arif Suner, Serdar Türkmen   +7 more
doaj   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Myocardial Performance Index in Nephrotic Syndrome

Journal of Clinical & Experimental Cardiology, 2018
Background: Primary or idiopathic nephrotic syndrome (PNS) is the most frequent form of Nephrotic Syndrome in children. There is an increased incidence of heart disease in patients with (PNS). Protein wasting and systemic inflammatory activation during PNS may contribute to cardiac remodeling and dysfunction.
Salah Mohamed Saleh, Khaled Sayed Mahmoud Elmaghraby, Ashraf Mohamed Abdelfadil, Hanem Saad Mohamed   +3 more
openaire   +1 more source

Tissue Doppler Echocardiography and Myocardial Performance Index in Patients with Scleroderma [PDF]

Journal of International Medical Research, 2005
In this study, left and right ventricular functions were examined echocardiographically in 22 patients with scleroderma and 22 healthy volunteers. Conventional and tissue Doppler echocardiography and myocardial performance indexes were used as measures of right and left ventricular global functions.
Yurtkuran, M, Cordan, J, Ediz, B, Kaderli, AA, Gullulu, S, Gullulu, M, Baran, I, Ozdemir, B, Ekbul, A   +8 more
openaire   +3 more sources

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source