Results 91 to 100 of about 554,014 (305)

Protecting the ischemic heart : pharmacological protection against myocardial ischemia in rats in vivo and in vitro [PDF]

, 2004
Today in Switzerland approximately 40% of all deaths are due to cardiovascular diseases. More than half of these are due to ischemic heart disease. Among the fatal consequences of ischemic heart disease are life-threatening arrhythmias and myocardial ...
Butz, Silvia
core   +1 more source

Nucleoside‐Modified mRNA Encoding Alpha‐Galactosidase A Ameliorates Fabry Disease Phenotypes in Human IPSC‐Derived Cardiomyocytes

Advanced Science, EarlyView.
Human iPSC‐derived Fabry cardiomyocytes exhibited broad transcriptional dysregulation, apoptosis, mitochondrial dysfunction, impaired reactive oxygen species handling, altered contractility, and abnormal calcium transient decay, potentially mediated by phospholamban hyperphosphorylation.
Malte Juchem, Lea Oehlsen, Sedef Ersoy, Jia Li Ye, Natalie Weber, Elisa Mohr, Wilson Agyapong, Junqing Liu, Maximilian Fuchs, Ke Xiao, Christopher Jahn, Reto Eggenschwiler, Tobias Cantz, Julia Beimdiek, Falk F. R. Buettner, Theresia Kraft, Jan Hegermann, Ivonne J. Knorr, Lisa Ernst, Linda Feldbrügge, Resa Puffert, Kevin Schmidt, Christian Bär, Jeannine Hoepfner, Thomas Thum   +24 more
wiley   +1 more source

Incidencia y significado clínico del grado de perfusión miocárdica durante la angioplastia primaria en el paciente con inf arto agudo del miocardio Incidence and clinical signification of myocardial perfusion degree during primary angioplasty in patients with acute myocardial infarction

Revista Colombiana de Cardiología, 2006
Introducción y objetivos: un porcentaje variable de pacientes con infarto agudo del miocardio tratados con intervención coronaria percutánea primaria, tiene compromiso de la perfusión miocárdica a pesar de reestablecer el flujo coronario epicárdico.
Nabil Hamdan, Édgar Hurtado, Pablo Castro, Luis Calderón, Germán Gómez, Gilberto Estrada   +5 more
doaj  

Data for comparison of computed tomography angiography and dynamic myocardial perfusion to detect significant stenosis by coronary angiography

Data in Brief, 2018
This article describes data related to a research article titled “Feasibility of dynamic myocardial CT perfusion using single-source 64-row CT”, Tomizawa et al. (in press) [1].
Nobuo Tomizawa, Shengpu Chou, Yusuke Fujino, Masaru Kamitani, Kodai Yamamoto, Shinichi Inoh, Takeshi Nojo, Kanako K. Kumamaru, Shigeki Aoki, Sunao Nakamura   +9 more
doaj   +1 more source

Role of DECT in coronary artery disease: a comparative study with ICA and SPECT

Diagnostic and Interventional Radiology, 2020
PURPOSEEarlier imaging techniques for coronary artery disease (CAD) focused primarily on either morphological or functional assessment of CAD.
Kamireddy V. Prasad Reddy, Manphool Singhal, Rajesh Vijayvergiya, Ashwani Sood, Niranjan Khandelwal   +4 more
doaj   +1 more source

SPARC Drives Podocyte Mitochondrial Damage and Ferroptosis in Diabetic Kidney Disease Following Klotho Deficiency

Advanced Science, EarlyView.
Klotho deficiency promotes podocyte mitochondrial dysfunction and ferroptosis through activation of the PKCα/CUX1/SPARC/TGFβ‐RII axis. SPARC emerges as a key mediator linking Klotho loss to podocyte injury in DKD and other kidney injury models, suggesting broader implications for CKD progression.
Qing Yang, Huimin Jiang, Chenyang Xiong, Xindi Zhou, Qinqin Tan, Han Xiao, Lan Qiu, Chun Gan, Yaxi Chen, Haiping Yang, Wei Jiang, Qiu Li   +11 more
wiley   +1 more source

Source, triggers and clinical implications of hyperlactemia in patients undergoing mitral valve surgery using Custodiol cardioplegia [PDF]

, 2013
Postoperative blood hyperlactaemia is an indicator of organ anaerobic metabolism and is associated with morbidity after cardiac surgery. This prospective study aims to explore the source, triggers and clinical implications for hyperlactaemia in patients ...
Zanchettin, Chiara, Angelini, Gianni D, Zoffoli, Giampaolo, Suleiman, M.Saadeh, Ascione, Raimondo, Polesel, Elvio, Mangino, Domenico, Venturini, Andrea   +7 more
core   +1 more source

Serial Molecular‐Microstructural Multimodal Intravascular Imaging of Atherosclerotic Plaques in Mice

Advanced Science, EarlyView.
A novel longitudinal molecular and microstructural intravascular imaging approach is developed to study murine atherosclerosis. The technique combines a unique surgical model with a miniaturized multimodal device to detect macrophage activity and lipid simultaneously.
Jiawen Li, Joanne T. M. Tan, Lei Xiang, Jiandi Liu, Ayla Hoogendoorn, Victoria A. Nankivell, Lauren Sandeman, Richard Le, Rouyan Chen, Robert A. McLaughlin, Peter J. Psaltis, Johan W. Verjans, Christina A. Bursill   +12 more
wiley   +1 more source

CD11b+CD43hiLy6Clo splenocyte‐derived macrophages exacerbate liver fibrosis via spleen–liver axis

Hepatology, EarlyView., 2022
A population of splenic monocytes migrate into the liver and shift to macrophages, which account for the exacerbation of liver fibrosis. Abstract Background and Aims Monocyte‐derived macrophages (MoMFs), a dominant population of hepatic macrophages under inflammation, play a crucial role in liver fibrosis progression.
Shaoying Zhang, Dan Wan, Mengchen Zhu, Guihu Wang, Xurui Zhang, Na Huang, Jian Zhang, Chongyu Zhang, Qi Shang, Chen Zhang, Xi Liu, Fanfan Liang, Chunyan Zhang, Guangyao Kong, Jing Geng, Libo Yao, Shemin Lu, Yongyan Chen, Zongfang Li   +18 more
wiley   +1 more source

Processing myocardial perfusion data [PDF]

, 2010
The invention relates to a system for processing cardiac data. The system comprises a processor that is arranged to obtain patient-specific myocardial perfusion data.
Breeuwer, Marcel; id_orcid, Olivan Bescos, Javier, Termeer, Maurice A.   +2 more
core   +1 more source