Results 111 to 120 of about 108,555 (300)

Positron Emission Tomography in the Diagnosis and Management of Coronary Artery Disease

Medicina, 2018
Cardiac positron emission tomography (PET) and positron emission tomography/computed tomography (PET/CT) are encouraging precise non-invasive imaging modalities that allow imaging of the cellular function of the heart, while other non-invasive ...
Eglė Kazakauskaitė, Diana Žaliaduonytė-Pekšienė, Eglė Rumbinaitė, Justas Keršulis, Ilona Kulakienė, Renaldas Jurkevičius   +5 more
doaj   +1 more source

Inhibition of Macrophage ARID3A Alleviates Myocardial Ischemia‐Reperfusion Injury After Heart Transplantation by Reducing THBS1/CD47 Signaling‐Mediated Neutrophil Extracellular Traps Formation

Advanced Science, EarlyView.
This study reveals that ARID3A in macrophages can transcriptionally regulate the THBS1‐CD47 axis after heart transplantation (HT), thereby inducing activated neutrophils to release NETs through the p38 MAPK signaling pathway. The itaconate derivative 4‐OI can inhibit ARID3A in macrophages and promote the accumulation of antioxidant factors, thereby ...
Hao Tian, Yonghong Xiong, Junbiao Zhan, Zhikun Lu, Yuxi Zhang, Yan Leng, Qin Huang, Zhongyuan Xia   +7 more
wiley   +1 more source

A randomized, placebo-controlled trial of late Na current inhibition (ranolazine) in coronary microvascular dysfunction (CMD): impact on angina and myocardial perfusion reserve. [PDF]

, 2015
AimsThe mechanistic basis of the symptoms and signs of myocardial ischaemia in patients without obstructive coronary artery disease (CAD) and evidence of coronary microvascular dysfunction (CMD) is unclear.
Anderson, R David, Bairey Merz, C Noel, Berman, Daniel S, Brown, Garrett H, Cook-Wiens, Galen, Handberg, Eileen M, Mehta, Puja K, Minissian, Margo B, Pepine, Carl J, Petersen, John W, Rogatko, André, Shaw, Leslee J, Shufelt, Chrisandra L, Shuster, Jonathan J, Thomson, Louise EJ, Wei, Janet   +15 more
core   +1 more source

Engineered Multifunctional Hydrogel Delivering Novel CBX7 Inhibitor Modulates Cuproptosis Via Liquid–Liquid Phase Separation to Restore Cardiac Function in Aged Myocardial Infarction

Advanced Science, EarlyView.
An age‐adapted therapy pairs δ‐Amyrenone, a CBX7 inhibitor, with an alginate hydrogel (CSAδ) to rescue infarcted elderly hearts. CSAδ disrupts CBX7–ATP7A liquid–liquid phase separation, restores ATP7A trafficking and copper efflux, suppresses cuproptosis, supplies oxygen, scavenges ROS, promotes M2 polarization, supports angiogenesis, and enhances ...
Jun Liu, Peng Qu, Jiao Shi, Tingting Liang, Yao Gu, Xue Li, Cui Ma, Danyang Zhao, Feila Liu, Qi Liang, Panke Cheng, Qian Lei   +11 more
wiley   +1 more source

Bidirectional ventricular tachycardia in cardiac sarcoidosis. [PDF]

, 2016
A 73-year-old man with history of pulmonary sarcoidosis was found to have runs of non-sustained bidirectional ventricular tachycardia (BVT) with two different QRS morphologies on a Holter monitor.
Benjamin, Mina M, Field, Michael E, Hayes, Kevin, Hoffmayer, Kurt S, Scheinman, Melvin M   +4 more
core   +2 more sources

The many ways to myocardial perfusion imaging.

The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of..., 2005
Myocardial perfusion imaging (MPI) is important for the management of patients with suspected or known coronary artery disease (CAD). Nuclear cardiology is the most widely used noninvasive approach for the assessment of myocardial perfusion. The available single-photon emission computed tomography (SPECT) flow agents are characterized by a rapid ...
CUOCOLO, ALBERTO, ACAMPA, WANDA, IMBRIACO, MASSIMO, DE LUCA, NICOLA, Iovino GL, SALVATORE, MARCO   +5 more
openaire   +4 more sources

Nanozymes for Non‐Neoplastic Diseases: Catalytic Therapy Redefined

Aggregate, EarlyView.
Non‐neoplastic diseases pose a significant health burden. Nanozymes, enzyme‐like nanomaterials, offer promising strategies for regulating oxidative stress and inflammation. This review explores their development, structure–function relationships, and therapeutic potential, with a focus on precision medicine through targeted delivery and multimodal ...
Ling Mei, Xikai Wang, Zhuang Hu, Jierui Yan, Xiaobo Wang, Haoran Wang, Ya Hou, Pengfei Zhang, Qihang Ding   +8 more
wiley   +1 more source

Cardiovascular risk factors and development of nomograms in an Italian cohort of patients with suspected coronary artery disease undergoing SPECT or PET stress myocardial perfusion imaging

Frontiers in Nuclear Medicine
IntroductionSingle-photon emission computed tomography (SPECT) and positron emission tomography (PET) are non-invasive nuclear medicine techniques that can identify areas of abnormal myocardial perfusion. We assessed the prevalence of cardiovascular risk
Rosario Megna, Mario Petretta, Carmela Nappi, Roberta Assante, Emilia Zampella, Valeria Gaudieri, Teresa Mannarino, Adriana D’Antonio, Roberta Green, Valeria Cantoni, Mariarosaria Panico, Wanda Acampa, Alberto Cuocolo   +12 more
doaj   +1 more source

Magnetic resonance multitasking for motion-resolved quantitative cardiovascular imaging. [PDF]

, 2018
Quantitative cardiovascular magnetic resonance (CMR) imaging can be used to characterize fibrosis, oedema, ischaemia, inflammation and other disease conditions.
Christodoulou, Anthony G, Li, Debiao, Nguyen, Christopher, Shaw, Jaime L, Wang, Nan, Xie, Yibin, Yang, Qi   +6 more
core   +2 more sources

Microgels for 3D Biofabrication

Aggregate, EarlyView.
This review highlights microgels as a versatile platform advancing biomanufacturing and tissue regeneration. It details their fabrication methods, core functions (bioprinting inks, suspension support baths, porous sacrificial scaffolds), and pivotal applications (drug delivery, dynamic cell culture microenvironments, tissue engineering scaffolds ...
Ting Xie, Huaibin Wang, Jieting Li, Leyan Xuan, Farzana Nazir, Long Chen, Zeyu Luo, Mian Wang, Yingling Miao, Dongyang Zhang, Wanlu Li, Guosheng Tang   +11 more
wiley   +1 more source