Results 131 to 140 of about 104,281 (302)

Protective Effects of Riociguat Against Contrast‐Induced Nephropathy: An Experimental and Machine Learning‐Based Study in Rats

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Contrast‐induced nephropathy (CIN) is an important cause of acute kidney injury following exposure to iodinated contrast media, and effective preventive strategies remain limited. This study investigated the renoprotective effects of riociguat, a soluble guanylate cyclase stimulator, in an experimental rat model of CIN and explored machine ...
Mustafa Begenc Tascanov   +10 more
wiley   +1 more source

Hemodynamic Significance of APEXCT Coronary Angiography Combined With Dynamic CT Myocardial Perfusion Imaging in Assessing Restenosis After Coronary Stenting

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study aimed to evaluate the hemodynamic significance of in‐stent restenosis (ISR) by using a combined anatomical‐functional approach with photon‐counting CT coronary angiography (APEX‐CT CTA) and dynamic CT myocardial perfusion imaging (CT‐MPI). We prospectively enrolled 239 symptomatic patients at least 9 months after PCI.
Liang‐Shi Wang   +6 more
wiley   +1 more source

Dynamic Mode Decomposition (DMD) for Low‐Latency Real‐Time Cardiac MRI

open access: yesMagnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To demonstrate dynamic mode decomposition (DMD) for high spatiotemporal low‐latency online reconstruction in 2D real‐time cardiac MRI. Methods DMD was applied to 2D spiral balanced steady state free precession (bSSFP) real‐time adult and fetal cardiac MRI at 0.55 T, with data from 10 healthy adult volunteers (3F/7M; age: 21–49; BMI: 20–
Ecrin Yagiz   +5 more
wiley   +1 more source

Current Status of Kidney Xenotransplantation in Basic Research

open access: yesOrgan Medicine, EarlyView.
Kidney xenotransplantation is a potential solution to the organ shortage for end‐stage kidney disease. This review systematically elaborates on the application advances of donor pig gene editing technologies, the molecular mechanisms and regulatory strategies of xenogeneic immune rejection, and the optimization approaches of immune compatibility ...
Yu Luo, Bingzhuo Liu, Weijie Lai
wiley   +1 more source

Fractional flow reserve versus intravascular ultrasound guidance for percutaneous coronary intervention in intermediate coronary stenoses: A systematic review and meta‐analysis

open access: yesPrecision Medical Sciences, EarlyView.
Fractional Flow Reserve versus Intravascular Ultrasound for guiding percutaneous coronary intervention in coronary artery disease: A systematic review and meta‐analysis of 5 studies (over 3,900 patients) showing comparable outcomes in MACE, mortality, and target vessel revascularization.
Sanket Patel   +13 more
wiley   +1 more source

Subdiaphragmatic activity-related artifacts in myocardial perfusion scintigraphy

open access: yesRadiology and Oncology
Myocardial perfusion imaging (MPI) with single photon emission computed tomography is an established non-invasive technique for assessing myocardial ischemia.
Strok Anja   +3 more
doaj   +1 more source

Metabolic engineering of adipose‐derived stem cell exosomes via arachidonic acid potentiates diabetic wound repair by orchestrating angiogenesis: A multi‐omics guided strategy

open access: yesVIEW, EarlyView.
AA‐Exos promotes angiogenesis and accelerates diabetic wound healing by activating the PI3K/AKT/mTOR pathway. Abstract Diabetic wounds are common and challenging complications of diabetes, characterized by delayed healing and an increased risk of infection.
Yujiao Cai   +7 more
wiley   +1 more source

Prognostic implications of quantified coronary atherosclerosis and myocardial perfusion in diabetes

open access: yesCardiovascular Diabetology
Background Coronary artery disease (CAD) is a major contributor to cardiovascular events in individuals with diabetes. Quantification of coronary atherosclerotic burden is now feasible from coronary computed tomography angiography (CTA) whereas positron ...
Matias Mäenpää   +12 more
doaj   +1 more source

The Clinical Utility of a Precision Medicine Blood Test Incorporating Age, Sex, and Gene Expression for Evaluating Women with Stable Symptoms Suggestive of Obstructive Coronary Artery Disease: Analysis from the PRESET Registry. [PDF]

open access: yes, 2019
Background: Evaluating women with symptoms suggestive of coronary artery disease (CAD) remains challenging. A blood-based precision medicine test yielding an age/sex/gene expression score (ASGES) has shown clinical validity in the diagnosis of ...
Budoff, Matthew J   +9 more
core   +1 more source

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