Results 151 to 160 of about 104,281 (302)

Regadenoson in the detection of coronary artery disease

open access: yesVascular Health and Risk Management, 2008
Christiane Buhr1, Mario Gössl2, Raimund Erbel1, Holger Eggebrecht11Department of Cardiology, West-German Heart Center Essen, University of Duisburg-Essen, Essen, Germany; 2Cardiovascular Diseases, Mayo Clinic College of Medicine, Rochester, MN 55905,
Christiane Buhr   +3 more
doaj  

Hepatocyte TrkB Acts as a Gatekeeper Against MASH‐Related Liver Fibrosis by Suppressing the TGFβ/CCL2 Axis and Macrophage Infiltration

open access: yesCell Proliferation, EarlyView.
Hepatocyte TrkB is identified as a critical gatekeeper against MASH‐related fibrosis. Mechanistically, TrkB inhibits the TGFβ/SMAD3/FOS axis to suppress CCL2 secretion, thereby blocking pathogenic macrophage recruitment and ameliorating liver fibrosis.
Yueying Chen   +11 more
wiley   +1 more source

Behind the scenes: how the EMILIN/Multimerin family shapes the cancer landscape

open access: yesThe FEBS Journal, EarlyView.
The EMILIN/Multimerin family members regulate key hallmarks of cancer—including apoptosis, angiogenesis, metastasis, and tumor microenvironment remodeling. As indicated, their function in immune evasion, drug resistance, and metabolic reprogramming remains largely unexplored.
Evelina Poletto   +9 more
wiley   +1 more source

The role of myocardial perfusion imaging in the screening of silent ischemia in diabetic patients

open access: yesIranian South Medical Journal, 2010
Background: More than 70%of diabetes patients die from cardiovascular causes. Furthermore, consequences of coronary artery disease (CAD) are more severe ,because myocardial ischemia is often silent in these patients.
Majid Assadi   +5 more
doaj  

Proteolysis at the extracellular matrix interface: Molecular architects and regulators in health and disease

open access: yesThe FEBS Journal, EarlyView.
The extracellular matrix (ECM) is a dynamic scaffold that orchestrates tissue architecture and cellular communication. A critical but underexplored interplay between proteases and cluster of differentiation molecules (CD) governs ECM turnover and directs cell fate.
David Jurnečka   +3 more
wiley   +1 more source

Giants in the cold: Morphological evidence for vascular heat retention in the viscera but not the skeletal muscle of the basking shark (Cetorhinus maximus)

open access: yesJournal of Fish Biology, EarlyView.
Abstract Fewer than 50 of the over 30,000 extant species of fishes have developed anatomical specializations facilitating endothermy in specific body regions. The plankton‐feeding basking shark (Cetorhinus maximus), traditionally classified as an ectotherm, was recently shown to have regionally endothermic traits such as centralized red muscle (RM ...
C. Antonia Klöcker   +9 more
wiley   +1 more source

Contrast‐enhanced CT—Nephrotoxic or not? A critical review of propensity‐score‐adjusted studies

open access: yesJournal of Internal Medicine, EarlyView.
Abstract Retrospective, propensity‐score‐adjusted (PSA) studies have indicated to practitioners in the field that contrast‐induced acute kidney injury (AKI) after contrast‐enhanced CT (CECT) is of minor importance or even non‐existent. This has led to controversies between clinicians demanding CECT not to miss any diagnoses and radiologists reluctant ...
Ulf Nyman   +6 more
wiley   +1 more source

Cell Therapy for Periodontal, Soft‐Tissue, and Craniofacial Regeneration

open access: yesJournal of Periodontal Research, EarlyView.
The clinical translation of mesenchymal stem/stromal cells (MSCs) represents a major advancement in dentistry, especially for periodontal, soft‐tissue, and craniofacial regeneration. However, several challenges remain to be addressed, including the absence of standardised protocols, limited scalability, regulatory hurdles, a lack of well‐controlled ...
Kamal Mustafa   +5 more
wiley   +1 more source

Evaluation of the Effect of Myocardial Localisation Errors on Myocardial Blood Flow Estimates from Myocardial Perfusion MRI [PDF]

open access: yes, 2010
Biglands, J   +6 more
core   +1 more source

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