Abstract Atrial fibrillation (AF), the most common clinical arrhythmia, is driven by inflammatory activation and oxidative stress, though precise molecular links remain unclear. This study identifies the P2X7 receptor as a key upstream regulator orchestrating proarrhythmic atrial remodeling through reactive oxygen species (ROS)‐mediated mitogen ...
Lingnan Zhang, Yeran Zhu, Xinshun Gu
wiley +1 more source
Myocardial Perfusion Imaging with Cardiovascular Magnetic Resonance in Nonischemic Cardiomyopathies: An In-Depth Review of Techniques and Clinical Applications. [PDF]
Sharka I +14 more
europepmc +1 more source
Redox Regulation and Oxidative Stress in Health and Disease: Mechanisms and Therapeutic Targeting
Reactive species serve crucial roles which are tightly regulated in both physiological as well as disease states. At physiological levels, these species are integral to redox signaling, while uncontrolled redox promotes disease pathology. This review examines the dysregulation of these processes.
Mohammad Hossein Azadi +2 more
wiley +1 more source
Efficacy of coronary computed tomography angiography and its fractional flow reserve in predicting myocardial ischemia in patients with obstructive coronary artery disease with positron emission tomography myocardial perfusion imaging as a reference standard. [PDF]
Wang T +6 more
europepmc +1 more source
ABSTRACT Purpose The objective of this study was to develop and evaluate an accelerated free‐breathing motion corrected and averaged late gadolinium enhancement MRI (FB PSIR‐MoCo LGE) protocols. Methods Simultaneous multi‐slice (SMS) bSSFP imaging with GC‐LOLA correction and a multiband factor of two was implemented into a FB PSIR‐MoCo LGE sequence ...
Grzegorz Tomasz Kowalik +11 more
wiley +1 more source
The Western Denmark Myocardial Perfusion Imaging Registry: A Review and Validation Study. [PDF]
Søby JH +12 more
europepmc +1 more source
ABSTRACT Purpose First‐pass perfusion cardiovascular MR (FPP‐CMR) enables the non‐invasive diagnosis of microcirculation and coronary artery disease. In free‐breathing FPP‐CMR, motion correction is usually performed in the image domain, requiring an initial reconstruction.
Elisa Moya‐Sáez +10 more
wiley +1 more source
Significance of Coronary Artery Calcifications and Ischemic Electrocardiographic Changes Among Patients Undergoing Myocardial Perfusion Imaging. [PDF]
Kokkinidis DG +9 more
europepmc +1 more source
ABSTRACT Purpose To develop a new method for free‐running three‐dimensional (3D) extracellular volume mapping of the heart in a single scan with mid‐scan contrast injection. Methods 3D cardiac MR imaging was performed with a single scan that acquired k‐space data continuously using an inversion recovery (IR) sequence with a spoiled gradient‐echo ...
Wonil Lee +8 more
wiley +1 more source

