Results 121 to 130 of about 129,108 (303)

Equine models in translational medicine: A comparative approach to human health

Animal Models and Experimental Medicine, EarlyView.
This diagram summarizes and contrasts rodent and equine models, outlining their strengths, limitations, and applications. Horses offer naturally occurring diseases, genetic and physiological similarities to humans, and suitability for longitudinal and clinical‐scale studies.
Shayan Boozarjomehri Amnieh, Katarzyna Ropka‐Molik   +1 more
wiley   +1 more source

IRF‐1 modulates hepatic ferroptosis and aggravates liver ischemia/reperfusion injury via DYRK1α

Animal Models and Experimental Medicine, EarlyView.
IRF‐1 modulates hepatic ferroptosis and aggravates liver ischemia/reperfusion injury via DYRK1α. Abstract Background The purpose is to define the contribution of the interferon regulatory factor‐1–dual‐specificity tyrosine phosphorylation‐regulated kinase 1α (IRF‐1–DYRK1α) axis to hepatocellular ferroptosis during liver ischemia/reperfusion injury ...
Jinping Zhang, Jinming Zhang, Siyuan Song, Mingyang Li, Liying Sun, Zhijun Zhu, Dongdong Lin   +6 more
wiley   +1 more source

Single-centre, single-blind, randomized, active-controlled phase-3 non-inferiority study to investigate the safety and efficacy of the cardioplegic solution Cardioplexol™

Frontiers in Cardiovascular Medicine
ObjectivesEffective and reliable cardioplegic cardiac arrest is crucial for maximizing myocardial protection and preserving postoperative contractile function. Aim of this study was to demonstrate, in line with an ongoing European registration procedure,
Hendrik T. Tevaearai Stahel, Gabriel Weiss, Gabriel Weiss, Peter Landowski, Peter Landowski, Sandra Folkmann, Sandra Folkmann, Marieluise Harrer, Marieluise Harrer, Bernard Voet, Martin Grabenwöger, Martin Grabenwöger, Martin Grabenwöger   +12 more
doaj   +1 more source

Myocardial damage in cardioplegia and cardiopulmonary bypass

, 2016
Cardiopulmonary bypass and cardioplegia are the most frequently used techniques in cardiac surgery. The level of cardiac mortality in the postoperative period depends on them both directly and indirectly.
A.О. Taratorina, V.S. Kolesnikov, G.G. Taradin, Ye.V. Yeshchenko, M.Т. Vatutin   +4 more
core  

Identificación de nuevos biomarcadores en los síndromes coronarios agudos [PDF]

, 2012
[spa] La aterosclerosis, engrosamiento de la pared arterial, puede progresar gradualmente hasta complicarse con la aparición de un trombo ocasionando una obstrucción brusca de una arteria con obliteración del flujo en el órgano irrigado por dicha arteria.
Cubedo Ràfols, Judit
core  

Chrysin alleviates pressure overload–induced myocardial remodeling through regulating the PI3K/AKT/NRF2 pathway–mediated oxidative stress response

Animal Models and Experimental Medicine, EarlyView.
In this study, we primarily simulated pathological myocardial remodeling induced by transverse aortic constriction surgery and found significant cardiac hypertrophy and fibrosis, characterized by deteriorated cardiac function. Oxidative stress response is considered as a pivotal pathological process, which contributes to inflammation and apoptosis of ...
Yijia Wang, Xing Feng, Shuhui Zhao, Yuchong Fu, Ao Zhang, Xiaofeng Shen, Bowen Yu, Yihao Wang, Jiahui Lin, Bing Zhang, Weiping Ji, Lianpin Wu, Xiaoling Guo   +12 more
wiley   +1 more source

Upper hemisternotomy vs. full sternotomy for hemiarch and proximal aortic replacement

Frontiers in Cardiovascular Medicine
IntroductionHemiarch replacement with proximal aortic replacement is seldom performed via upper hemisternotomy (UHS). We report our surgical technique and postoperative outcomes in 11 patients who underwent UHS for hemiarch and proximal aortic ...
Jeffrey A. Zucker, Vishal N. Shah, Joshua R. Chen, Christopher Pritting, Colin King, Jacqueline McGee, Megary McCoy, Konstadinos Plestis   +7 more
doaj   +1 more source

Remote preconditioning by aortic constriction: affords cardioprotection as classical or other remote ischemic preconditioning? Role of iNOS

, 2011
Dose remote preconditioning by aortic constriction (RPAC) affords cardioprotection similar to classical or other remote ischemic preconditioning stimulus?
Ashok Sharma, Akash Sharma, Ashish Sharma, Ashish Tiwari, Divya Sharma, Arshee Munajjam, Kunal Kishore, Rita Kumari, Shyam Agarwal, B.P. Srinivasan, Bhawna Vaishnav, Richa Sharma   +11 more
core  

Therapeutic Applications of Stimuli‐Based Release and Engineering of Extracellular Vesicles

Advanced NanoBiomed Research, EarlyView.
This review summarizes the effects of endogenous and exogenous stimuli, their effects on the natural release of extracellular vesicles, as well as their uptake and release. It also gives an overview of stimuli‐responsive EVs and their therapeutic applications. Extracellular vesicles (EVs), nano‐ to microsized lipid bilayer membrane‐bound particles, are
Gloria Kemunto, Kristen Dellinger
wiley   +1 more source

Hypoglycemic Effects and Myocardial Protection of Sanghuangporus vaninii Polysaccharide on Diabetes Rats

Shipin gongye ke-ji
To examine the hypoglycemic effects and myocardial protection of Sanghuangporus vaninii polysaccharide (SP) in T2DM rats, these effects were assessed in rats fed a high glucose and high fat diet combined with streptozotocin (STZ).
Yue CHANG, Yue WU, Jianfeng GUO, Weiyuan ZHAO, Yuantian LU, Di LIU   +5 more
doaj   +1 more source