Results 141 to 150 of about 3,082,827 (354)

PAF Triggered Pyroptotic NETosis Aggravates Myocardial Ischemia/Reperfusion Injury

Advanced Science, EarlyView.
Platelet activating factor (PAF) secreted by cardiomyocytes during MI/R, drives NETs formation and subsequent NETosis. PAF/NETosis signaling activation is an initiative and causal factor in driving MI/R injury. This study identifies dapagliflozin as a potent NETosis inhibitor, and demonstrates that manipulating PAF‐NETosis signal by dapagliflozin or ...
Jiawei Wu, Shule Zhang, Ruofan Du, Lina Kang, Guodong Zhao, Xue Bao, Haochi Yang, Ziqing Xie, Tianyu He, Huiyong Sun, Haiping Hao, Lijuan Cao   +11 more
wiley   +1 more source

A cardioplegia oxigenada na proteção miocárdica durante a cirurgia cardíaca: estudo clínico e enzimático Oxygenated cardioplegia in myocardial protection during cardiac surgery: a clinical and enzymatic study

Brazilian Journal of Cardiovascular Surgery, 1988
A cardioplegia tem sido reconhecida como um fator muito importante na proteção oo miocárdio. Sabe-se que, mesmo a 15ºC, o coração consome oxigênio. Testes in vitro demonstraram que a cardioplegia cristalóide libera mais oxigênio que a sangüínea.
Potiguara S. da Costa, Sérgio Nunes Pereira, Luiz B Moraes, Renato S Marques, Manoel A. P Alvarez, Carlos A. S Daudt, Luciane M Deboni, Cleonir Raskoski, Mauro F Silva   +8 more
doaj  

Single-centre, single-blind, randomized, active-controlled phase-3 non-inferiority study to investigate the safety and efficacy of the cardioplegic solution Cardioplexol™

Frontiers in Cardiovascular Medicine
ObjectivesEffective and reliable cardioplegic cardiac arrest is crucial for maximizing myocardial protection and preserving postoperative contractile function. Aim of this study was to demonstrate, in line with an ongoing European registration procedure,
Hendrik T. Tevaearai Stahel, Gabriel Weiss, Gabriel Weiss, Peter Landowski, Peter Landowski, Sandra Folkmann, Sandra Folkmann, Marieluise Harrer, Marieluise Harrer, Bernard Voet, Martin Grabenwöger, Martin Grabenwöger, Martin Grabenwöger   +12 more
doaj   +1 more source

The Effects of Fire Fighting and On-Scene Rehabilitation on Hemostatis [PDF]

, 2010
Fire fighting is a dangerous occupation – in part because firefighters are called upon to perform strenuous physical activity in hot, hostile environments.
Fahey, George C., Fernhall, B., Horn, Gavin P., Illinois Fire Service Institute, Petruzzello, Steven J., Smith, Denise L., University of Illinois at Urbana-Champaign, Woods, Jeffrey   +7 more
core  

Decoding the Cardiac Immune Microenvironment and Fibroblast Crosstalk in Radiotherapy Combined with Immunotherapy‐Induced Cardiac Fibrosis Based on Single‐Cell Transcriptomic Analysis

Advanced Science, EarlyView.
This study highlights that radioimmunotherapy drives crosstalk between fibroblasts and immune cells (especially macrophages) in the cardiac microenvironment, with IL‐6 as the key mediator, and tocilizumab alleviates cardiac fibrosis by targeting this interplay.
Yuxi Luo, Ying Yu, Zhimin Zeng, Yanxin Chen, Yali Yi, Zhiqin Lu, Fujuan Zeng, Peng Xu, Daya Luo, Leifeng Chen, Anwen Liu   +10 more
wiley   +1 more source

Myocardial protection

The Journal of Thoracic and Cardiovascular Surgery, 1979
David M. Lolley, Jefferson F. Ray, William O. Myers, Richard D. Sautter   +3 more
openaire   +3 more sources

Should socioeconomic factors be considered as traditional risk factors for cardiovascular disease, as confounders, or as risk modifiers? [PDF]

, 2008
A large number of studies show that cardiovascular disease and its traditional risk factors are associated with socioeconomic conditions. However, their etiological role in the development of cardiovascular outcomes is not always well understood ...
De Vogli, R., Marmot, M.
core  

Administration of Interleukin-15 Peptide Improves Cardiac Function in a Mouse Model of Myocardial Infarction. [PDF]

, 2020
Interleukin-15 is a pleotropic factor, capable of modulating metabolism, survival, proliferation, and differentiation in many different cell types.
Ameri, Kurosh, Bayardorj, Dulguun, Fredkin, Maxwell, Fuh, Eric, Nguyen, Vien, Samurkashian, Raffi, Yeghiazarians, Yerem   +6 more
core  

Oral Celastrol Nanomedicine Targeting Intestinal Antigen‐Presenting Cells to Effectively Mitigate Autoimmune Uveitis via Gut‐Retina Axis

Advanced Science, EarlyView.
Oral nanoCEL exhibits effective intestinal targeting of antigen‐presenting cells and restores the Th17/Treg balance in lymph nodes and spleen, ultimately protecting the blood‐retinal barrier by inhibiting peripheral immune cell infiltration and suppressing retinal glial cell activation.
Jinrun Chen, Yuqin Wu, Bofei Xu, Jiabei Hou, Yijing Li, Yuhan Hu, Yutuo Zhu, Wenqiao Zhang, Shuqi Feng, Huanting Jin, Yuchen Cheng, Yuanyuan Jin, Jianhong Zhou, Xingyi Li   +13 more
wiley   +1 more source

Upper hemisternotomy vs. full sternotomy for hemiarch and proximal aortic replacement

Frontiers in Cardiovascular Medicine
IntroductionHemiarch replacement with proximal aortic replacement is seldom performed via upper hemisternotomy (UHS). We report our surgical technique and postoperative outcomes in 11 patients who underwent UHS for hemiarch and proximal aortic ...
Jeffrey A. Zucker, Vishal N. Shah, Joshua R. Chen, Christopher Pritting, Colin King, Jacqueline McGee, Megary McCoy, Konstadinos Plestis   +7 more
doaj   +1 more source