Results 81 to 90 of about 68,817 (283)

Meta‐analysis of sotagliflozin, a dual sodium‐glucose‐cotransporter 1/2 inhibitor, for heart failure in type 2 diabetes

ESC Heart Failure, Volume 12, Issue 2, Page 968-979, April 2025.
Abstract Sodium‐glucose co‐transporters (SGLTs) mediate sodium and glucose transport across cell membranes. SGLT2 inhibitors have a recognized place within heart failure (HF) guidelines. We evaluated the effect of sotagliflozin on HF and cardiovascular outcomes in participants with type 2 diabetes. Scopus, Medline, Embase and Central were searched from
Maria Anna Bantounou, Panagiotis Sardellis, Josip Plascevic, Ribeya Awaes‐Mahmood, Justyna Kaczmarek, Daniel Black Boada, Rosa Thuemmler, Sam Philip   +7 more
wiley   +1 more source

TRAF1 Exacerbates Myocardial Ischemia Reperfusion Injury via ASK1–JNK/p38 Signaling

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
Background After acute myocardial infarction, the recovery of ischemic myocardial blood flow may cause myocardial reperfusion injury, which reduces the efficacy of myocardial reperfusion.
Weipan Xu, Li Zhang, Yi Zhang, Kai Zhang, Yongbo Wu, Daoqun Jin   +5 more
doaj   +1 more source

NEDD4 ameliorates myocardial reperfusion injury by preventing macrophages pyroptosis. [PDF]

Cell Commun Signal, 2023
Sun W, Lu H, Cui S, Zhao S, Yu H, Song H, Ruan Q, Zhang Y, Chu Y, Dong S.   +9 more
europepmc   +1 more source

Interventional therapies for chronic heart failure: An overview of recent developments

ESC Heart Failure, Volume 12, Issue 2, Page 1081-1094, April 2025.
Abstract Heart failure (HF), the final manifestation of most cardiovascular diseases, has become a major global health concern, affecting millions of individuals. Despite basic drug treatments, patients present with high morbidity and mortality rates. However, recent advancements in interventional therapy have shown promising results in improving the ...
Bingchen Guo, Si Shi, Yutong Guo, Jie Xiong, Bo Wang, Zengxiang Dong, Dianyu Gao, Yingfeng Tu   +7 more
wiley   +1 more source

GSDMD contributes to myocardial reperfusion injury by regulating pyroptosis. [PDF]

Front Immunol, 2022
Ye X, Zhang P, Zhang Y, Luan J, Xu C, Wu Z, Ju D, Hu W.   +7 more
europepmc   +1 more source

Curcumin attenuates myocardial ischemia-reperfusion injury

Oncotarget, 2017
Cardiovascular diseases (CVDs) are at a badly high-risk of morbidity and mortality in the world.Our study was attempted to investigate the cardioprotective role of curcumin. Hearts injury was assessed in isolated hearts and the rats of coronary artery ligated.The inhibition of pro-inflammatory cytokines was observed by curcumin in coronary artery ...
Shuo Wang, Kang-Jun Yu, Qing Ye, Kun Liu, Shuang-Long Zhang, Fei Wang, Qing-Sheng You, Hong-Lin Chen, Qi Lu   +8 more
openaire   +4 more sources

Transendocardial injection of expanded autologous CD34+ cells after myocardial infarction: Design of the EXCELLENT trial

ESC Heart Failure, Volume 12, Issue 2, Page 1455-1463, April 2025.
Abstract Aims The extent of irreversible cardiomyocyte necrosis after acute myocardial infarction (AMI) is a major determinant of residual left ventricular (LV) function and clinical outcome. Cell therapy based on CD34+ cells has emerged as an option to help repair the myocardium and to improve outcomes.
Jerome Roncalli, François Roubille, Nicolas Meyer, Giulio Pompilio, Lionel Leroux, Philippe Henon, Guillaume Trebuchet, Anthony Criquet, Matthieu de Kalbermatten, Eric Saloux, Alain Manrique, Pierre‐Yves Marie, Deepak L. Bhatt, Scott D. Solomon, Gilles Montalescot, David E. Newby, Faiez Zannad, on behalf of the EXCELLENT Trial Investigators   +17 more
wiley   +1 more source

The roles of Th cells in myocardial infarction

Cell Death Discovery
Myocardial infarction, commonly known as a heart attack, is a serious condition caused by the abrupt stoppage of blood flow to a part of the heart, leading to tissue damage.
Jun Liu, Feila Liu, Tingting Liang, Yue Zhou, Xiaohan Su, Xue Li, Jiao Zeng, Peng Qu, Yali Wang, Fuli Chen, Qian Lei, Gang Li, Panke Cheng   +12 more
doaj   +1 more source

JAK2/STAT3 pathway mediates beneficial effects of pterostilbene on cardiac contractile and electrical function in the setting of myocardial reperfusion injury. [PDF]

Physiol Res, 2022
Li S, Wang H, Zhou Y.
europepmc   +1 more source

Superoxide dismutase conjugated to polyethylene glycol provides sustained protection against myocardial ischemia/reperfusion injury in canine heart. [PDF]

, 1988
Yasuo Tamura, L G, Edward M. Driscoll, Paul Hoff, Bruce Α. Freeman, K P Gallagher, Benedict R. Lucchesi   +6 more
openalex   +1 more source