Results 1 to 10 of about 7,598 (289)

Ischemic preconditioning affects phosphosites and accentuates myocardial stunning while reducing infarction size in rats [PDF]

Frontiers in Cardiovascular Medicine
Background and aimsIschemic preconditioning (IPC), i.e., brief periods of ischemia, protect the heart from subsequent prolonged ischemic injury, and reduces infarction size. Myocardial stunning refers to transient loss of contractility in the heart after
Ahmed Elmahdy, Ahmed Elmahdy, Aaron Shekka Espinosa, Aaron Shekka Espinosa, Yalda Kakaei, Yalda Kakaei, Tetiana Pylova, Tetiana Pylova, Abhishek Jha, Abhishek Jha, Ermir Zulfaj, Maryna Krasnikova, Maryna Krasnikova, Amin Al-Awar, Amin Al-Awar, Zahra Sheybani, Zahra Sheybani, Valentyna Sevastianova, Valentyna Sevastianova, Evelin Berger, Amirali Nejat, Linnea Molander, Linnea Molander, Erik Axel Andersson, Erik Axel Andersson, Elmir Omerovic, Elmir Omerovic, Shafaat Hussain, Shafaat Hussain, Björn Redfors, Björn Redfors, Björn Redfors   +31 more
doaj   +8 more sources

Myocardial stunning [PDF]

Majalah Kedokteran Andalas, 2017
Myocardial stunning adalah penurunan fungsi miokardium pada periode iskemia dan reperfusi. Iskemia dapat menyebabkan perubahan di dalam struktur miosit yang berusaha mengembalikan aliran darah normal. Salah satu teori yaitu teori “Calcium Overload” dapat
Maria Lousiana, Miftah Irramah
doaj   +5 more sources

ATP—Sensitive Potassium Channel Opener Diazoxide Reduces Myocardial Stunning in a Porcine Regional With Subsequent Global Ischemia Model [PDF]

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022
Background ATP‐sensitive potassium channels are inhibited by ATP and open during metabolic stress, providing endogenous myocardial protection. Pharmacologic opening of ATP potassium channels with diazoxide preserves myocardial function following ...
Ana K. Velez, Eric Etchill, Katherine Giuliano, Sean Kearney, Melissa Jones, Jie Wang, Brian Cho, Mary Beth Brady, Jeffrey Dodd‐o, Joseph M. Meyer, Jennifer S. Lawton   +10 more
doaj   +2 more sources

Myocardial stunning secondary to erroneous administration of intravenous epinephrine [PDF]

SAGE Open Medical Case Reports, 2023
Epinephrine is a commonly used medication for emergent conditions, such as anaphylaxis, respiratory distress, and shock. However, its versatility can also lead to iatrogenic errors in dosages, concentrations, and routes of administration. In this case, a
Girish Pathangey, Rohitha Moudgal, Christopher Lee, Stanislav Henkin   +3 more
doaj   +2 more sources

Metformin preconditioning protects against myocardial stunning and preserves protein translation in a mouse model of cardiac arrest [PDF]

Journal of Molecular and Cellular Cardiology Plus, 2023
Cardiac arrest (CA) causes high mortality due to multi-system organ damage attributable to ischemia-reperfusion injury. Recent work in our group found that among diabetic patients who experienced cardiac arrest, those taking metformin had less evidence ...
Cody A. Rutledge, Claudia Lagranha, Takuto Chiba, Kevin Redding, Donna B. Stolz, Eric Goetzman, Sunder Sims-Lucas, Brett A. Kaufman   +7 more
doaj   +2 more sources

Serum neprilysin levels are associated with myocardial stunning after ST-elevation myocardial infarction [PDF]

BMC Cardiovascular Disorders, 2020
Background Left ventricular remodeling following ST-elevation myocardial infarction (STEMI) is associated with poor outcome, including heart failure (HF).
Damien Legallois, Clémence Macquaire, Amir Hodzic, Stéphane Allouche, Ismaïl El Khouakhi, Alain Manrique, Paul Milliez, Eric Saloux, Farzin Beygui   +8 more
doaj   +2 more sources

A review on fueling recovery: the role of metabolic modulation in non-obstructive myocardial stunning [PDF]

European Journal of Medical Research
Non-obstructive myocardial stunning is characterized by transient myocardial contractile dysfunction despite preserved coronary perfusion. Although increasingly recognized, it remains a diagnostic and therapeutic challenge in cardiology.
Uğur Özkan, Kenan Yalta, Muhammet Gürdoğan, Nicholas G. Kounis, Servet Altay   +4 more
doaj   +2 more sources

Cardiac Assessment and Takotsubo-stunning among COPD-exacerbations in-Hospital (CATCH study): when the lungs break your heart—protocol for a prospective observational cohort study [PDF]

BMJ Open Respiratory Research
Introduction Acute exacerbation of chronic obstructive pulmonary disease (AECOPD) may cause stress-induced transient acute cardiac dysfunction through myocardial stunning, in the form of exacerbation-triggered Takotsubo syndrome (referred to as Takotsubo
N David Åberg, Emma Westerlind, Mazdak Tavoly, Roxana Mincheva, Lowie Vanfleteren, Axel Andersson, Johan-Emil Bager, Sara Zooq, Peter Hällgren Nordhage, Johan Lönnbro, Micael Oliveira Diniz, Kanya Said, Per Thysell, Tore Hedbäck   +13 more
doaj   +2 more sources

Safety and feasibility of hyperkalemic cardioplegia with diazoxide in cardiac surgery: The Cardioplegia with Diazoxide in Cardiac Surgery TrialCentral MessagePerspective [PDF]

JTCVS Open
Background: We have demonstrated cardioprotection by the adenosine triphosphate–sensitive potassium (KATP) channel opener diazoxide in multiple animal models in an effort to reduce myocardial stunning following cardiac surgery.
AlleaBelle Bradshaw, MD, Jessica B. Briscoe, MD, Lisa Fornaresio, PhD, Zyriah Robinson, BS, Michelle Carvajal Villalba, MD, Shivani Shirodkar, MBBS, MPH, Hamza Aziz, MD, Jennifer S. Lawton, MD   +7 more
doaj   +2 more sources

Randomized Controlled Trial of Intradialytic Cycling as Kidney Exercise Rehabilitation for Cardiac Stunning in Hemodialysis (TICKERS_HD): A Clinical Research Protocol [PDF]

Canadian Journal of Kidney Health and Disease
Introduction: People with hemodialysis-dependent kidney failure experience significantly higher cardiovascular (CV) morbidity, mortality, symptom burden, and cognitive impairment compared to the general population.
Paul N. Bennett, Jarrin D. Penny, Christopher W. McIntyre, Jessica Vanderlinden, Megan S. Borkum, Gisell Castillo, David Collister, Bonnie Corradetti, Todd A. Duhamel, Haley Farion, Emilie Ford, Eric Garcia, Ruth Getachew, Shilpanjali Jesudason, Mercedeh Kiaii, Richard Le Leu, Justin Presseau, Claudio Rigatto, Ashley K. Seitz, Mitra Shirazi, Anita Soni, Krista Stewart, Brett Tarca, Karthik Tennankore, Nancy Verdin, Reid Whitlock, Ken Wilund, Stephanie Thompson, Jennifer M. MacRae, Clara Bohm   +29 more
doaj   +2 more sources