Results 21 to 30 of about 337,957 (243)

Safety and feasibility of hyperkalemic cardioplegia with diazoxide in cardiac surgery: The Cardioplegia with Diazoxide in Cardiac Surgery TrialCentral MessagePerspective [PDF]

JTCVS Open
Background: We have demonstrated cardioprotection by the adenosine triphosphate–sensitive potassium (KATP) channel opener diazoxide in multiple animal models in an effort to reduce myocardial stunning following cardiac surgery.
AlleaBelle Bradshaw, MD, Jessica B. Briscoe, MD, Lisa Fornaresio, PhD, Zyriah Robinson, BS, Michelle Carvajal Villalba, MD, Shivani Shirodkar, MBBS, MPH, Hamza Aziz, MD, Jennifer S. Lawton, MD   +7 more
doaj   +2 more sources

Randomized Controlled Trial of Intradialytic Cycling as Kidney Exercise Rehabilitation for Cardiac Stunning in Hemodialysis (TICKERS_HD): A Clinical Research Protocol [PDF]

Canadian Journal of Kidney Health and Disease
Introduction: People with hemodialysis-dependent kidney failure experience significantly higher cardiovascular (CV) morbidity, mortality, symptom burden, and cognitive impairment compared to the general population.
Paul N. Bennett, Jarrin D. Penny, Christopher W. McIntyre, Jessica Vanderlinden, Megan S. Borkum, Gisell Castillo, David Collister, Bonnie Corradetti, Todd A. Duhamel, Haley Farion, Emilie Ford, Eric Garcia, Ruth Getachew, Shilpanjali Jesudason, Mercedeh Kiaii, Richard Le Leu, Justin Presseau, Claudio Rigatto, Ashley K. Seitz, Mitra Shirazi, Anita Soni, Krista Stewart, Brett Tarca, Karthik Tennankore, Nancy Verdin, Reid Whitlock, Ken Wilund, Stephanie Thompson, Jennifer M. MacRae, Clara Bohm   +29 more
doaj   +2 more sources

Q50, an Iron-Chelating and Zinc-Complexing Agent, Improves Cardiac Function in Rat Models of Ischemia/Reperfusion-Induced Myocardial Injury [PDF]

, 2013
Background: Reperfusion of ischemic myocardium may contribute to substantial cardiac tissue damage, but the addition of iron chelators, zinc or zinc complexes has been shown to prevent heart from reperfusion injury.
Faragó, Nóra, Hirschberg Kristóf, Korkmaz S, Merkely Béla Péter, Radovits, Tamás, Hirschberg, Kristóf, Barnucz E, Karck Matthias, Szabó Gábor, Fábián Gabriella, Gyuris Márió, Puskás László G., Loganathan Sivakkanan, Radovits Tamás, Weymann Alexander, Szabó, Csaba, Fábián, Gabriella, Loganathan, Sivakkanan, Karck, Matthias, Merkely, Béla, Kanizsai Iván, Faragó Nóra, Hegedűs Péter, Korkmaz, Sevil, Li Shiliang, Hegedűs, Péter, Gyuris, Márió, Szabó Csaba, Zubarevich Alina, Li, Shiliang, Puskás, László G., Korkmaz Sevil, Ózsvári, Béla, Zubarevich, Alina, Weymann, Alexander, Li S, Merkely Béla, Barnucz, Enikő, Puskás László, Kanizsai, Iván, Szabó, Gábor, Barnucz Enikő, Loganathan S, Ózsvári Béla   +43 more
core   +2 more sources

Non-invasive intradialytic percutaneous perfusion monitoring: a view to the heart through the skin

Frontiers in Nephrology, 2023
IntroductionThe life-sustaining treatment of hemodialysis (HD) induces recurrent and cumulative systemic circulatory stress resulting in cardiovascular injury.
Jarrin D. Penny, Jarrin D. Penny, Jarrin D. Penny, Lisa Hur, Lisa Hur, Fabio R. Salerno, Fabio R. Salerno, Dickson Wong, M. Hussain Jan, Christopher W. McIntyre, Christopher W. McIntyre, Christopher W. McIntyre, Christopher W. McIntyre   +12 more
doaj   +1 more source

Effects of Rosuvastatin and Pitavastatin on Ischemia-Induced Myocardial Stunning in Dogs

Journal of Pharmacological Sciences, 2008
Incomplete recovery of myocardial contraction after reperfusion following brief ischemia is called the “stunning phenomenon” in an animal experiment.
Kumi Satoh, Akira Takaguri, Mai Itagaki, Seiichiro Kano, Kazuo Ichihara   +4 more
doaj   +1 more source

The effectiveness and cost-effectiveness of computed tomography screening for coronary artery disease : systematic review [PDF]

, 2006
Coronary heart disease (CHD) is one of the main causes of mortality and morbidity in the UK and other Western countries. The disease can be asymptomatic until the first event, which may be a fatal myocardial infarction (heart attack).
Black, C. (Corrinda), Cummins, E. (Ewen), N Waugh, L McIntyre, E Cummins, C Black, Walker, S., Hillis, G. S., Waugh, Norman, G Hillis, S Walker, McIntyre, Linda   +11 more
core   +1 more source

Connexins and Nitric Oxide Inside and Outside Mitochondria: Significance for Cardiac Protection and Adaptation

Frontiers in Physiology, 2018
Irreversible myocardial damage happens in the presence of prolonged and severe ischemia. Several phenomena protect the heart against myocardial infarction and other adverse outcomes of ischemia and reperfusion (IR), namely: hibernation related to stunned
Maria Shvedova, Yana Anfinogenova, Yana Anfinogenova, Sergey V. Popov, Dmitriy N. Atochin, Dmitriy N. Atochin   +5 more
doaj   +1 more source

Toxic Myocardial Injury in a Patient With Coronary Atherosclerosis, Caused by Acute Poisoning With Gaseous Chlorine

Неотложная медицинская помощь, 2021
Acute chlorine gas poisoning leads to activation of the sympathetic nervous system and, as a consequence, dysfunction of the cardiovascular system (CVS). We report a clinical case of toxic myocardial injury with gaseous  chlorine.
K. G. Alidzhanova, A. Yu. Moiseyeva, A. M. Pashayeva, M. M. Potskhveriya, G. A. Gazaryan, S. Yu. Kambarov   +5 more
doaj   +1 more source

Myocardial stunning: A therapeutic conundrum [PDF]

, 1995
Dobutamine and pyruvate are two inotropic agents with different mechanisms of action. Although both agents alter postischemic myocardial dysfunction, their potential metabolic effects in the setting of in vivo myocardial stunning have not been addressed.
Lasley, Robert D., Mentzer, Robert M., Zhou, Zhandong, Bünger, Rolf, Hegge, Julia O.   +4 more
core   +1 more source

Myocardial Stunning During Gated Spect Indicates Presence of Severe Coronary Artery Disease. Biswas,G.** Shukkur, A.M.* Sayed, M.** Alsayed, Y.** and Masoud, M.** Department of Nuclear Medicine **and Cardiology*, Chest Hospital, Kuwait. [PDF]

Egyptian Journal of Nuclear Medicine, 2010
Transient left ventricular dysfunction is known to occur in patients following stress in coronary artery disease [CAD]. Also known as myocardial stunning, it is a transient phenomenon occurring during myocardial ischemia after treadmill exercise or ...
doaj   +1 more source