Results 91 to 100 of about 7,598 (289)

Considerations for drug trials in hypertrophic cardiomyopathy

ESC Heart Failure, Volume 12, Issue 2, Page 1095-1112, April 2025.
Abstract Hypertrophic cardiomyopathy (HCM) is a heterogeneous condition with potentially serious manifestations. Management has traditionally comprised therapies to palliate symptoms and implantable cardioverter‐defibrillators to prevent sudden cardiac death. The need for disease‐modifying therapies has been recognized for decades.
John P. Farrant, Matthias Schmitt, Anna B. Reid, Clifford J. Garratt, William G. Newman, Aneil Malhotra, Rhys Beynon, Masliza Mahmod, Betty Raman, Robert M. Cooper, Dana Dawson, Thomas Green, Sanjay K. Prasad, Anvesha Singh, Susanna Dodd, Hugh Watkins, Stefan Neubauer, Christopher A. Miller   +17 more
wiley   +1 more source

myocardial responses to ischemia

Терапевтический архив, 2010
The paper details the types of a myocardial response to impaired blood flow, such as myocardial stunning, hibernation, ischemic preconditioning, warm-up phenomenon, ischemic postconditoning, remodeling, and infarction.
Viktor Gennad'evich Borisenko, Elena Aleksandrovna Gubareva, Azamat Khalidovich Kade, V G Borisenko, E A Gubareva, A Kh Kade   +5 more
doaj  

Adaptive Reductions in Left Ventricular Diastolic Compliance Protect the Heart From Stretch-Induced Stunning

JACC: Basic to Translational Science, 2019
Summary: Swine subjected to 2 weeks of repetitive pressure overload (RPO) exhibited significant myocyte loss, but left ventricular (LV) systolic function was preserved, and chamber dilatation did not occur. Instead, myocardial remodeling characterized by
Brian R. Weil, PhD, George Techiryan, BS, Gen Suzuki, MD, PhD, Filip Konecny, DVM, PhD, John M. Canty, Jr., MD   +4 more
doaj   +1 more source

Sacubitril/valsartan preserves regional cardiac function following myocardial infarction in rats

ESC Heart Failure, Volume 12, Issue 2, Page 1304-1315, April 2025.
Parts of the figure were drawn by using pictures from Servier Medical Art. Servier Medical Art by Servier is licensed under a Creative Commons Attribution 3.0 Unported License (https://creativecommons.org/licenses/by/3.0/). Abstract Aims Sacubitril/valsartan (Sac/Val) is used for treatment of heart failure. The effect of Sac/Val on regional dysfunction
Einar Sjaastad Nordén, Bård Andre Bendiksen, Kaja Knudsen Bergo, Emil Knut Stenersen Espe, Gary McGinley, Almira Hasic, Ida Marie Hauge‐Iversen, Hege Katrin Ugland, Xin Shen, Michael Frisk, Nishani S. Mabotuwana, William E. Louch, Rizwan I. Hussain, Lili Zhang, Ivar Sjaastad, Alessandro Cataliotti, Geir Christensen   +16 more
wiley   +1 more source

Table1_Ischemic preconditioning affects phosphosites and accentuates myocardial stunning while reducing infarction size in rats.docx [PDF]

Background and aimsIschemic preconditioning (IPC), i.e., brief periods of ischemia, protect the heart from subsequent prolonged ischemic injury, and reduces infarction size. Myocardial stunning refers to transient loss of contractility in the heart after
Erik Axel Andersson (18158083), Linnea Molander (18158080), Elmir Omerovic (85139), Shafaat Hussain (800683), Aaron Shekka Espinosa (18158053), Zahra Sheybani (18158071), Ermir Zulfaj (18158062), Abhishek Jha (673945), Yalda Kakaei (18158056), Björn Redfors (4044476), Valentyna Sevastianova (18158074), Tetiana Pylova (18158059), Ahmed Elmahdy (18158050), Amirali Nejat (18158077), Maryna Krasnikova (18158065), Amin Al-Awar (18158068), Evelin Berger (183544)   +16 more
core   +1 more source

Cardiogenic shock mortality according to Aetiology in a Mediterranean cohort: Results from the Shock‐CAT study

ESC Heart Failure, Volume 12, Issue 2, Page 1336-1345, April 2025.
Abstract Aims Mortality in cardiogenic shock (CS) remains elevated, with the potential for CS causes to impact prognosis and risk stratification. The aim was to investigate in‐hospital prognosis and mortality in CS patients according to aetiology. We also assessed the prognostic accuracy of CardShock and IABP‐SHOCK II scores.
Cosme García‐García, Teresa López‐Sobrino, Esther Sanz‐Girgas, Maria R. Cueto, Jaime Aboal, Pablo Pastor, Irene Buera, Alessandro Sionis, Rut Andrea, Judit Rodríguez‐López, Jose Carlos Sánchez‐Salado, Carlos Tomas, Jordi Bañeras, Albert Ariza, Josep Lupón, Antoni Bayés‐Genís, Ferran Rueda, Grup de Treball de Cures Agudes Cardiològiques Societat Catalana de Cardiologia   +17 more
wiley   +1 more source

Table3_Ischemic preconditioning affects phosphosites and accentuates myocardial stunning while reducing infarction size in rats.docx [PDF]

Background and aimsIschemic preconditioning (IPC), i.e., brief periods of ischemia, protect the heart from subsequent prolonged ischemic injury, and reduces infarction size. Myocardial stunning refers to transient loss of contractility in the heart after
Erik Axel Andersson (18158083), Linnea Molander (18158080), Elmir Omerovic (85139), Shafaat Hussain (800683), Aaron Shekka Espinosa (18158053), Zahra Sheybani (18158071), Ermir Zulfaj (18158062), Abhishek Jha (673945), Yalda Kakaei (18158056), Björn Redfors (4044476), Valentyna Sevastianova (18158074), Tetiana Pylova (18158059), Ahmed Elmahdy (18158050), Amirali Nejat (18158077), Maryna Krasnikova (18158065), Amin Al-Awar (18158068), Evelin Berger (183544)   +16 more
core   +1 more source

Mechanical Unloading Properties of Axial Flow Pumps and their Effect on Myocardial Stunning [PDF]

, 1995
Postischemic myocardial dysfunction affects morbidity and mortality in patients with coronary artery disease. It is known that mechanical unloading of the left heart ventricle can positively influence postischemic myocardial dysfunction. In this respect
W. Flameng, F. R. Waldenberger, B. Meyns, E. Pongo, E. De Ruyter, P. Wouters   +5 more
core   +1 more source

FDG PET/CT imaging and circulating biomarkers of inflammation in desmoplakin cardiomyopathy

ESC Heart Failure, Volume 12, Issue 2, Page 1485-1489, April 2025.
Abstract Aims Inflammation has been implicated in the pathogenesis of desmoplakin (DSP) cardiomyopathy, and retrospective studies have described abnormal myocardial fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) findings in symptomatic patients eventually diagnosed with DSP cardiomyopathy.
Sanjay Divakaran, Vinay Randhawa, Usman A. Tahir, Matthew Robertson, Anam A. Waheed, Anna Perillo, Leanne Barrett, Ron Blankstein, Mark W. Feinberg, Marcelo F. Di Carli, Neal K. Lakdawala   +10 more
wiley   +1 more source

Myocardial stunning in exercise-induced ischemia in dogs: lack of late preconditioning [PDF]

, 2001
Late preconditioning (PC) against myocardial stunning develops after coronary artery occlusion (CAO) at rest and subsequent reperfusion. We investigated whether late PC occurs after exercise-induced ischemia (high-flow ischemia) in dogs.
Olivier Parent De Curzon, Alain Berdeaux, Bijan Ghaleh, Luc Hittinger, Jean-François Giudicelli, Renaud Tissier   +5 more
core   +1 more source