Results 111 to 120 of about 206,512 (311)
Advanced Science, EarlyView.This research conducts an in‐depth investigation of cell‐type‐specific regulatory mechanisms underlying molecular and complex phenotypes through integrative analysis of multitissue single‐nucleus RNA sequencing, bulk RNA‐seq, and genome‐wide association study (GWAS) data in pigs.
Lijuan Chen +31 more
wiley +1 more source
Protective Effect of Nigella Sativa Oil on Myocardium in Streptozotocininduced Diabetic Rats
, 2019 Eren Altun
openalex +2 more sources
Endogenous Thrombospondin 1 Protects the Pressure-Overloaded Myocardium by Modulating Fibroblast Phenotype and Matrix Metabolism [PDF]
, 2011 Ying Xia +7 more
openalex +1 more source
Targeting Adipose Tissue Function Protects Against Heart Failure with Preserved Ejection Fraction
Advanced Science, EarlyView.This study explores the role adipose tissue (AT) phenotypes have in determining cardiovascular outcomes in an obesity‐related heart failure with preserved ejection fraction (HFpEF) model. Pharmacological induction of thermogenesis promoted resilience to HFpEF‐induced remodeling of AT and conferred cardioprotection. Surgical and genetic models confirmed
Jordan Jousma +11 more
wiley +1 more source
Modifying Glucose Metabolism Reverses Memory Defects of Alzheimer's Disease Model at Late Stages
Advanced Science, EarlyView.Using spatial transcriptomics, we show that ferul enanthate (SL‐ZF‐01) reverses episodic‐like memory deficits in aged, but not young, Alzheimer’s disease (AD) mice. SL restores glucose metabolism and Glucose Transporter 1/3 expression via an ‘Aging‐AD‐Rescue’ pattern, rescuing deficits seen in aged AD mice.
Fang Liu +14 more
wiley +1 more source
Isolation and characterization of AMP deaminase from mammalian (rabbit) myocardium
, 1993 Jay K. Thakkar +4 more
openalex +2 more sources
ACCURACY OF PATHOLOGIC Q WAVE ON ELECTROCARDIOGRAPHY TO PREDICT NON-VIABLE MYOCARDIUM
, 2023 Kashif Ali Hashmi +4 more
openalex +2 more sources
Advanced Science, EarlyView.METTL1 and its mediated m7G tRNA modification are significantly up‐regulated after partial hepatectomy (PHx). Overexpression of METTL1 improves the efficiency of liver regeneration after PHx, increases the proliferation of hepatocytes, and accelerates the recovery of liver function.
Manling Huang +18 more
wiley +1 more source
Advanced Science, EarlyView.PDAC has a poor prognosis due to chemoresistance. We revealed that MCU upregulation is associated with chemoresistance and stemness in PDAC. MCU‐mediated Ca2+ influx induced ER stress, activating the PERK‐ATF4/NRF2 axis to enhance PSAT1/SLC711 expression and glutathione synthesis, reducing ROS and maintaining stemness.
Zekun Li +17 more
wiley +1 more source
Regional End-Systolic Circumferential Strain Demonstrates Reduced Function in Remote Myocardium after Anterior STEMI [PDF]
Steve Leung +3 more
openalex +1 more source