Results 141 to 150 of about 449,111 (345)

Delivery of Molecular Hydrogen for Precision Immunomodulation: Mechanisms, Detection Methods, and Applications

Advanced Science, EarlyView.
This review focuses on the immunomodulatory mechanisms of molecular hydrogen, the recent detection methods, and the classification advanced molecular hydrogen delivery materials. It provides a detailed description of their applications in areas such as arthritis, chronic wounds, cardiovascular injury, tumors, and bacterial infections, aiming to enhance
Gangfeng Li, Hannan Cui, Ruixiao Fan, Guming Liu, Zishuo Hou, Yibo Zhang, Xuanming Che, Tengjiao Wang, Hongbo Wei, Peng Li   +9 more
wiley   +1 more source

Downhill running regulates cardiac immune response through GCN2. [PDF]

PLoS One
Bai X, Zhang W, Zhang Y, Xu X.
europepmc   +1 more source

Quantifying the Release of Biomarkers of Myocardial Necrosis from Cardiac Myocytes and Intact Myocardium.

Clinical Chemistry, 2017
J. Marjot, T. Kaier, E. D. Martin, Shiney S Reji, O. Copeland, Mohammed Iqbal, Bob Goodson, S. Hamren, S. Harding, M. Marber   +9 more
semanticscholar   +1 more source

PFKM‐Driven Lactate Overproduction Promotes Atrial Fibrillation via Triggering Cardiac Fibroblasts Histone Lactylation

Advanced Science, EarlyView.
The upregulation of PFKM activates glycolysis, thereby enhancing lactate production in atrial tissue. Atrial lactate accumulation promotes global lactylation and H3K18 lactylation in atrial fibroblasts. P300‐mediated H3K18 lactylation up‐regulates TGF‐β1 transcription, leading to fibroblast activation and thereby contributing to atrial fibrosis.
Ning Fang, Ning Zhang, Xiaohui Jiang, Sen Yan, Zhiqi Wang, Qianhui Gao, Mingcheng Xu, Lin Mu, Xiaoming Li, Jiuling Chen, Song Zhang, Yu Duan, Fengxiang Yun, Luyifei Li, Yun Zhang, Yongtai Gong   +15 more
wiley   +1 more source

Rotating Frame Relaxation Time Mapping for the Visualization of the Sinoatrial Node Without Contrast Agent. [PDF]

NMR Biomed
Li Y, Casula V, Huhta T, Mailhiot S, Tolkkinen K, Karjalainen J, Liimatainen T.   +6 more
europepmc   +1 more source

Gut Metabolite Indole‐3‐Propionic Acid Regulates Macrophage Autophagy Through PPT1 Inhibiting Aging‐Related Myocardial Fibrosis

Advanced Science, EarlyView.
IPA is an intestinal tryptophan metabolite whose effects decline with decreased heart function. Supplementing IPA can alleviate the aging‐related myocardial fibrosis through PPT1. PPT1 is a key protein localized to lysosomes, and IPA can restore macrophage autophagy function by regulating PPT1 expresssions, thereby reducing aging‐related myocardial ...
Jing Lu, Hongyan Wang, Haiyu Zhang, Jiahao Li, Hanqi Li, Qiuyu Chen, Dongyu Han, Jialiang Liu, Lin Lv, Jie Xiong, Keying Yuan, Xianpeng Wei, Siqi Sheng, Fukai Liu, Yuanqi Shi, Zengxiang Dong, Yue Li   +16 more
wiley   +1 more source

Calcium Flux in the Mammalian Ventricular Myocardium [PDF]

, 1963
G. A. Langer, A. J. Brady
openalex   +1 more source

Human iPSC-derived myocardium-on-chip with capillary-like flow for personalized medicine.

Biomicrofluidics, 2017
Bradley W Ellis, A. Acun, U. I. Can, P. Zorlutuna   +3 more
semanticscholar   +1 more source

Cytokine Storm Induction Linked to Multi‐Organ Failure in Fatal Jellyfish Stings

Advanced Science, EarlyView.
N. nomurai is the most important injurious species in the coastal area of China. Model construction, omics analysis, mechanism exploration, and intervention measures of N. nomurai envenomation are performed in the current study, and it suggested that cytokine storm played an important role in pathogenesis.
Yichao Wang, Yi Wang, Fengling Yang, Jingbo Chen, Xiaoyu Geng, Qing Sun, Jinyu Zhang, Chang Liu, Jie Lv, Xiaochuan Hou, Yongfang Wang, Huiyan Lin, Jing Zhang, Lingxin Chen, Bing Yan, Liang Xiao   +15 more
wiley   +1 more source

Matrisome remodeling in the myocardium of hypertrophic cardiomyopathy; novel targets for molecular diagnostics. [PDF]

Front Cell Dev Biol
Ibrahim AM, Elfawy HA, Terracciano CM, Yacoub M.   +3 more
europepmc   +1 more source