Results 241 to 250 of about 449,111 (345)

Endothelial‐Derived CCL7 Promotes Macrophage Polarization and Aggravates Septic Acute Lung Injury via CCR1‐Mediated STAT1 Succinylation

Advanced Science, EarlyView.
During sepsis, pulmonary vascular endothelial cells secrete chemokine CCL7, which plays a pivotal role in facilitating the infiltration of C‐C motif chemokine receptor 1‐positive (CCR1+) macrophages into lung tissue. Activation of the CCL7–CCR1 axis enhances the succinylation of STAT1 mediated by KAT2A, thereby driving metabolic reprogramming and ...
Xue Li, Yuqin Long, Yunxi Zhu, Jiahui Gu, Ping Zhou, Changhong Miao   +5 more
wiley   +1 more source

Targeted ablation of the distal Purkinje-myocardium interface for premature ventricular complex-induced cardiomyopathy by delayed Purkinje conduction-induced re-excitation: a case report. [PDF]

Eur Heart J Case Rep
Ter Bekke RMA, van Rooij T, Volders PGA, Hocini M.   +3 more
europepmc   +1 more source

The effect of cardiac glycosides on the contractile function of the myocardium

, 1969
K. F. Kravets
openalex   +2 more sources

Mitochondrial Transplantation Augments the Reparative Capacity of Macrophages Following Myocardial Injury

Advanced Science, EarlyView.
Mitochondrial transplantation induces macrophage polarization toward an anti‐inflammatory M2 phenotype, enhances their reparative capacities, and facilitates mitochondrial transfer to cardiomyocytes, collectively promoting tissue repair and functional recovery post‐myocardial infarction.
Yuning Zhang, Xiaolei Sun, Yawei Jin, Kanghui Chen, Lu Zhang, Xiong Gao, Mohan Li, Ze Yuan, Jianguo Jia, Aijun Sun, Junbo Ge   +10 more
wiley   +1 more source

High resolution-dynamic characterization of cardiac masses: radio-frequency spoiled 3D gradient echo sequence. [PDF]

Br J Radiol
Peker E, Ünal S, Ergüden RE, Yılmazer Zorlu NS, Bozer Uludağ S.   +4 more
europepmc   +1 more source

Macrophage Zc3h12c Limits Tissue Inflammation and Injury via Alternative Splicing of Pre‐mRNA

Advanced Science, EarlyView.
This work defines the context‐dependent function of Zc3h12c in macrophages using the Tnfrsf11a‐Cre system. It reveals Zc3h12c's dual mechanism—regulating RNA degradation and alternative splicing—with STAT1 as a key target. The findings elucidate a novel post‐transcriptional pathway and identify STAT1 isoforms as potential therapeutic targets for kidney
Chenyu Li, Julian Aurelio Marschner, Yoshihiro Kusunoki, Ningxin Zhang, Xiaoxin Li, Hao Deng, Zhibo Zhao, Kanako Watanabe‐Kusunoki, Zhihui Zhu, Yan Xu, Stefanie Steiger, Maciej Lech, Katalin Susztak, Christian Schulz, Hans‐Joachim Anders   +14 more
wiley   +1 more source

Excessive left ventricular trabeculations mimicking a thrombus. [PDF]

Eur Heart J Case Rep
Singh G, Shotwell M, Kalra D.
europepmc   +1 more source

Engineering DNA Origami Captors for TGFβ1 Sequestration to Enhance Tumor Immune Modulation and Therapy

Advanced Science, EarlyView.
Programmable DNA framework captors effectively deplete circulatingtransforming growth factor‐β1 (TGFβ1) through fast systemic clearance and reshape the tumor immune microenvironment, alleviating immunosuppression to inhibit tumor progression. Abstract Efficient modulation of pivotal immune‐regulatory molecules to leverage the tumor microenvironment ...
Xiao Chen, Dunfang Liu, Jiahui Jin, Han Yao, Yao Sheng, Yarong Liu, Jingwei Sun, Yang Yang   +7 more
wiley   +1 more source

SGLT2 Inhibitor Treatment Is Associated With Reduced Cardiac Glucose Metabolism: A Matched FDG-PET Cohort Study. [PDF]

JACC Adv
Sperry BW, Almohtasib Y, Ghaly R, Abdel Jawad M, Sauer AJ, Bateman TM.   +5 more
europepmc   +1 more source