Precision therapies for genetic epilepsies in 2025: Promises and pitfalls
Epilepsia Open, EarlyView.Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang +3 more
wiley +1 more source
Using dezocine to prevent etomidate-induced myoclonus: a meta-analysis of randomized trials
Drug Design, Development and Therapy, 2017 Objective This study was designed to evaluate the efficacy and safety of preinjection of dezocine in preventing etomidate-induced myoclonus. Methods PubMed, Embase, The Cochrane Library, and China National Knowledge Infrastructure (CNKI) were searched to
Yu Zhu +3 more
semanticscholar +1 more source
Generalized myoclonic epilepsy with photosensitivity in juvenile dogs caused by a defective DIRAS family GTPase 1 [PDF]
, 2017 The clinical and electroencephalographic features of a canine generalized myoclonic epilepsy with photosensitivity and onset in young Rhodesian Ridgeback dogs (6 wk to 18 mo) are described.
Arumilli, Meharji +21 more
core +1 more source
Absence seizures: Update on signaling mechanisms and networks
Epilepsia Open, EarlyView.Abstract Absence seizures (AS) are a hallmark of genetic generalized epilepsies (GGE), characterized by brief episodes of impaired consciousness accompanied by electroencephalographic spike‐and‐wave discharges (SWDs). Traditionally attributed to cortico‐thalamo‐cortical (CTC) dysrhythmia, emerging evidence suggests a more intricate pathophysiological ...
Ozlem Akman, Filiz Onat
wiley +1 more source
Opsoclonus-myoclonus syndrome - case report [PDF]
, 2020 Adéla Škvorová, Kateřina Matějová
openalex +1 more source
Opsoclonus-myoclonus syndrome associated with a nasopharyngeal tumor in an adult: a case report [PDF]
, 2015 INTRODUCTION: Opsoclonus-myoclonus syndrome is a rare autoimmune syndrome usually seen in children and very rarely in adults. It typically presents with a triad of opsoclonus, myoclonus and ataxia, and is most often associated with a tumor or after an ...
Andrew J Kinshuck +7 more
core +1 more source
Epileptic drop attacks: More than just atonic seizures
Epilepsia Open, EarlyView.Abstract “Drop attacks” are not officially defined by the International League Against Epilepsy. Seizures are characterized by a sudden loss of control over the trunk and posture, leading to falls and injuries, and resolving within a few seconds. Accurately diagnosing the type of seizure is usually difficult due to limitations in clinical documentation
Tomonori Ono +3 more
wiley +1 more source
Effect of pretreatment with midazolam on etomidate-induced myoclonus: A meta-analysis
Journal of International Medical Research, 2017 Objective To investigate the effect of pretreatment with midazolam on myoclonus induced by etomidate injection. Methods A meta-analysis was performed using Review Manager software, version 5.2.
Chengmao Zhou +3 more
semanticscholar +1 more source
Effects of dance therapy on balance, gait and neuro-psychological performances in patients with Parkinson's disease and postural instability [PDF]
, 2012 Postural Instability (PI) is a core feature of Parkinson’s Disease (PD) and a major cause of falls and disabilities. Impairment of executive functions has been called as an aggravating factor on motor performances. Dance therapy has been shown effective
Agnetti, Virgilio +6 more
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