Results 191 to 200 of about 78,026 (273)

Chronic and acute mediators of passive viscoelasticity in human skeletal muscle fibres

Experimental Physiology, EarlyView.
Abstract The cellular viscoelastic modulus in skeletal muscle tissue responds dynamically to chronic stressors, such as age and exercise. Passive tissue mechanics can also be sensitive to acute stimuli, such as mechanical loading and/or activation‐induced muscle fatigue.
Grace E. Privett, Austin W. Ricci, Karen Wiedenfeld Needham, Damien M. Callahan   +3 more
wiley   +1 more source

TRPV2 mediates stress resilience in mouse cardiomyocytes. [PDF]

Commun Biol
Dong Y, Wang G, Ujihara Y, Chen Y, Yoshida M, Nakamura K, Katanosaka K, Naruse K, Katanosaka Y.   +8 more
europepmc   +1 more source

Acute alterations in blood lactate in the setting of transient stress induced myocardial ischaemia

Experimental Physiology, EarlyView.
Abstract An elevation in resting venous blood lactate ([La−]b) levels in conditions of myocardial hypoperfusion is associated with adverse prognosis and survival. This investigation aimed to assess changes in venous [La−]b levels induced by dobutamine stress in the presence and absence of myocardial ischaemia and adverse outcomes at 1 year.
Jamie M. O'Driscoll, Elliot Smith, Matchel Bibat, Jamie J. Edwards, Claire Compton, Konstantina Kipourou, Damian Coleman, Jonathan Wiles, Eliane Cunliffe, Anna Marciniak, Rajan Sharma   +10 more
wiley   +1 more source

Inhibition of Soluble Epoxide Hydrolase Reduces Inflammation and Myocardial Injury in Arrhythmogenic Cardiomyopathy. [PDF]

JACC Basic Transl Sci
Panigrahy D, Kelly AG, Quinlivan KM, Wang W, Yang J, Hwang SH, Gillespie M, Howard IV, Bueno-Beti C, Asimaki A, Penna V, Lavine K, Edin ML, Zeldin DC, Hammock BD, Saffitz JE.   +15 more
europepmc   +1 more source

Exploring the respiratory efficacy of combined chronic glucocorticoid and antioxidant interventions in the mdx mouse: The PREDNAC trial

Experimental Physiology, EarlyView.
Abstract Duchenne muscular dystrophy (DMD) is characterized by respiratory muscle injury and weakness, ultimately leading to respiratory failure. Impaired respiratory muscle performance, fibrosis and inflammation in early disease are evident in the dystrophin‐deficient mdx mouse model of DMD.
Michael N. Maxwell, Ben T. Murphy, Fiona B. McDonald, Ken D. O'Halloran   +3 more
wiley   +1 more source

α- and β-myosin II can be non-uniformly distributed within the cardiac sarcomere. [PDF]

iScience
Hayes JB, Willet AH, Caplan LR, Knapik EW, Tyska MJ, Burnette DT.   +5 more
europepmc   +1 more source

Physical exercise intervention in glycogen storage disease IIIa: Feasibility and multisystem benefits

Experimental Physiology, EarlyView.
Abstract Glycogen storage disease III (GSD‐III) is caused by an inherited deficiency of the glycogen debranching enzyme. Affecting the liver, muscle and heart, GSD‐IIIa is the most common GSD‐III subtype. We evaluated the feasibility and safety of a physical exercise intervention in patients with GSD‐IIIa and its effects at the multisystem level.
Asunción Bustos‐Sellers, Almudena Montalvo‐Pérez, Araceli Boraita, Gonzalo Saco‐Ledo, Lidia B. Alejo, David Barranco‐Gil, Pedro L. Valenzuela, Nerea López‐Maldonado, Roser Ferrer‐Costa, Javier Esparcia‐Estrela, Celia Monteagudo‐López, Tomàs Pinós, Alejando Santos‐Lozano, Alejandro Lucia, Alfredo Santalla   +14 more
wiley   +1 more source

Role of GPCR Signaling in Anthracycline-Induced Cardiotoxicity. [PDF]

Cells
Biswal N, Harish R, Roshan M, Samudrala S, Jiao X, Pestell RG, Ashton AW.   +6 more
europepmc   +1 more source

Isolation of cardiac myocytes and measurement of myocyte shortening v1 [PDF]

, 2019
Gustavo Marchini, Ismar N. Cestari, Idágene A. Cestari   +2 more
openaire   +2 more sources

A human skeletal muscle cross‐bridge model to characterize the role of metabolite accumulation in muscle fatigue

Experimental Physiology, EarlyView.
Abstract Skeletal muscle fatigue is accompanied by the accumulation of metabolites, such as adenosine diphosphate (ADP), inorganic phosphate (Pi), and protons (H+). However, we lack a comprehensive understanding of the contribution of these metabolic changes to the development of muscle fatigue during intense exercise and the underlying mechanisms.
John I. Hendry, Muhammet Enes Erol, Gwenael Layec, Edward P. Debold, Shivendra G. Tewari, Anders Wallqvist, Venkat R. Pannala   +6 more
wiley   +1 more source