Results 251 to 260 of about 73,235 (299)
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Experimental Eye Research, 2016
Myofibroblasts are activated in response to tissue injury with the primary task to repair lost or damaged extracellular matrix. Enhanced collagen secretion and subsequent contraction - scarring - are part of the normal wound healing response and crucial to restore tissue integrity.
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Myofibroblasts are activated in response to tissue injury with the primary task to repair lost or damaged extracellular matrix. Enhanced collagen secretion and subsequent contraction - scarring - are part of the normal wound healing response and crucial to restore tissue integrity.
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Advances in Anatomic Pathology, 2004
Malignant tumors composed of myofibroblasts are increasingly being recognized, but their existence remains controversial. Currently accepted examples within this category represent spindle cell or pleomorphic neoplasms of the soft tissues with a spectrum of histological grades.
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Malignant tumors composed of myofibroblasts are increasingly being recognized, but their existence remains controversial. Currently accepted examples within this category represent spindle cell or pleomorphic neoplasms of the soft tissues with a spectrum of histological grades.
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The Myofibroblast in Neoplasia
1999Since its discovery in granulation tissue of healing wounds, now over a quarter of a century ago [22], the myofibroblast has been described in: (1) normal tissue; (2) diverse responses to injury and repair phenomena; (3) quasi-neoplastic proliferative conditions; (4) the stromal response to certain forms of neoplasia; and (5) benign and malignant ...
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50 Years of Myofibroblasts: How the Myofibroblast Concept Evolved
2021Myofibroblasts are key cells in mediating normal wound contraction and promoting connective tissue deformations characteristic of fibrosis and scarring. Five decades ago, myofibroblasts were discovered in electron micrographs of wound granulation tissue as fibroblastic cells containing microfilaments that are organized in bundles like those present in ...
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Inflammatory myofibroblastic tumors
Annals of Surgical Oncology, 2004AbstractIntroductionInflammatory myofibroblastic tumors (IMT) while uncommon may arise within numerous organs. Historically, the literature regarding IMT has been confined to small one organ case series, with few reviews encompassing multiple anatomic sites, and little data regarding adjuvant treatment.MethodsA review of patients with IMT treated at ...
Stephen J, Kovach +6 more
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The Myofibroblast in Dupuytren’s Contracture
Hand Clinics, 1991Dupuytren's contracture nodules, but not cords, contain myofibroblasts. These cells, which combine many electron microscopic, physiologic, and immunohistochemical characteristics of fibroblasts and smooth muscle cells, are probably the active force of contraction.
R, Rudolph, J, Vande Berg
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Myofibroblastic Tumors in Children
Surgical Pathology Clinics, 2010Pediatric myofibroblastic tumors comprise a clinically and pathologically heterogeneous group of neoplasms, including benign tumors, those of intermediate biologic potential, and frankly malignant examples (Box 1). Proper classification is critical for appropriate prognostication, clinical management, and, in some cases, identification of familial ...
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The American Journal of Dermatopathology, 1981
S, Lipper, L B, Kahn, R L, Reddick
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S, Lipper, L B, Kahn, R L, Reddick
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Inflammatory myofibroblastic tumour.
Canadian journal of surgery. Journal canadien de chirurgie, 2009Inflammatory myofibroblastic tumours (IMTs), previously accepted as a subtype of the group of tumours called inflammatory pseudotumours, are now recognized to comprise their own, discrete diagnosis. Since IMTs can arise from various anatomic locations,(1,2) they concern almost every subspecialty in surgical oncology. The management of these tumours can
Firat, Ozgur +3 more
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Inflammatory myofibroblastic tumour
Seminars in Diagnostic Pathology, 2016While initially controversial, the proposal that a subset of inflammatory pseudotumours were myofibroblastic neoplasms is now acknowledged. Inflammatory myofibroblastic tumour is a spindle cell neoplasm of intermediate biological potential that may arise in a wide range of anatomic sites but has a particular propensity for the lung and abdominal soft ...
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