Results 101 to 110 of about 59,231 (244)
Evaluation of Immunological Response to TLR2 and α-SMA in Crohn’s Disease and Ulcerative Colitis
Gastroenterology InsightsInflammatory bowel diseases (IBDs) represent multifactorial chronic inflammatory conditions of the gastrointestinal tract. The main IBDs are Crohn’s disease (CD) and ulcerative colitis (UC). CD may cause perforation, stricture or transmural inflammation,
Anthea Miller +8 more
doaj +1 more source
Advances and Challenges in Micro/Nanocarrier‐Based Dermal Drug Delivery Systems for Acne Treatment
Advanced NanoBiomed Research, EarlyView.Topical acne treatment faces challenges from skin barriers and complex causes. Micro/nanocarriers improve drug delivery by enhancing bioavailability, targeting, and duration. Combining carriers creates synergistic effects for systematic intervention.
Jintao Yang +7 more
wiley +1 more source
Revista de gastroenterologia de Mexico, 2004 Our objective was to present a case of inflammatory myofibroblastic tumor of the colon.Inflammatory myofibroblastic tumors are uncommon. They originate from soft tissues, their appearance is more frequent in childhood and your adulthood and these tumors are composed of myofibroblastic cells, leukocytes, and plasmatic cells.
Ernesto, Salgado-Sánchez +4 more
openaire +1 more source
Advanced NanoBiomed Research, EarlyView.Using a 3D cell culture model of the fibrotic barrier in pancreatic cancer, this work shows that inhibiting NUAK2 kinase in pancreatic stellate cells enhances macromolecular drug delivery. Mechanistically, NUAK2 inhibition disrupted actin stress fiber assembly to downregulate collagen I expression, thus enhancing macromolecular permeability.
Misaki Nakamura +14 more
wiley +1 more source
Wound Repair Using PVA–CA Electrospun Dressings and Cold Plasma In Vivo
Journal of Applied Polymer Science, EarlyView.In vivo wound healing evaluation of different treatments in a murine excisional wound model. (a) Representative photographs of wound closure at 3, 7, and 14 days post‐treatment for the different groups: Control, PVA‐CA, PVA‐CA‐Ag, NTP, PVA‐CA‐NTP, and PVA‐CA‐Ag‐NTP. (b) Experimental design showing six treatment groups with n = 18 wounds per group.
Jonalba M. Pereira +6 more
wiley +1 more source
Cytokine Pathways Driving Diverse Tissue Pathologies in Rheumatoid Arthritis
Arthritis &Rheumatology, EarlyView.Rheumatoid arthritis (RA) is a complex systemic disorder characterized primarily by articular inflammation and destruction with associated functional loss and reduced quality of life. RA is also associated with extra‐articular disease, such as that of the lung, with potentially devastating clinical consequences. The critical importance of comorbidities,
Aurelie Najm +2 more
wiley +1 more source
Ogerin induced activation of Gpr68 alters tendon healing
FASEB BioAdvancesSatisfactory outcomes after acute tendon injuries are hampered by a fibrotic healing response. As such, modulation of extracellular matrix deposition and remodeling represents an important intervention point to improve healing. During fibrosis, matrix is
Andrew Rodenhouse +9 more
doaj +1 more source
Arthritis &Rheumatology, EarlyView.Objective Beyond its role as a ribosome‐targeting antibiotic, linezolid was recently shown to modulate immune responses by inhibiting mitochondrial translation. Because mitochondrial dysfunction is implicated in various fibrotic diseases, including systemic sclerosis (SSc), this study aimed to evaluate the antifibrotic potential of linezolid and ...
Xuezhi Hong +13 more
wiley +1 more source
Arthritis &Rheumatology, Accepted Article.Objective Dermal Systemic Sclerosis (SSc) fibroblasts and their exosomes can activate keratinocytes in SSc, with lncRNA H19 (H19) highlighted as the most upregulated RNA in their cargo compared to healthy control (HC). The role of H19 in SSc pathogenesis has never been investigated.
Begoña Caballero‐Ruiz +3 more
wiley +1 more source