Results 211 to 220 of about 61,389 (261)
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Myofibroblasts

Experimental Eye Research, 2016
Myofibroblasts are activated in response to tissue injury with the primary task to repair lost or damaged extracellular matrix. Enhanced collagen secretion and subsequent contraction - scarring - are part of the normal wound healing response and crucial to restore tissue integrity.
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Myofibroblastic Malignancies

Advances in Anatomic Pathology, 2004
Malignant tumors composed of myofibroblasts are increasingly being recognized, but their existence remains controversial. Currently accepted examples within this category represent spindle cell or pleomorphic neoplasms of the soft tissues with a spectrum of histological grades.
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The Myofibroblast in Neoplasia

1999
Since its discovery in granulation tissue of healing wounds, now over a quarter of a century ago [22], the myofibroblast has been described in: (1) normal tissue; (2) diverse responses to injury and repair phenomena; (3) quasi-neoplastic proliferative conditions; (4) the stromal response to certain forms of neoplasia; and (5) benign and malignant ...
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50 Years of Myofibroblasts: How the Myofibroblast Concept Evolved

2021
Myofibroblasts are key cells in mediating normal wound contraction and promoting connective tissue deformations characteristic of fibrosis and scarring. Five decades ago, myofibroblasts were discovered in electron micrographs of wound granulation tissue as fibroblastic cells containing microfilaments that are organized in bundles like those present in ...
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Inflammatory myofibroblastic tumors

Annals of Surgical Oncology, 2004
AbstractIntroductionInflammatory myofibroblastic tumors (IMT) while uncommon may arise within numerous organs. Historically, the literature regarding IMT has been confined to small one organ case series, with few reviews encompassing multiple anatomic sites, and little data regarding adjuvant treatment.MethodsA review of patients with IMT treated at ...
Stephen J, Kovach   +6 more
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Myofibroblasts: Molecular crossdressers

2001
Myofibroblasts are unique mesenchymal cells with properties inherent to both muscle and nonmuscle cells. They are widely distributed in embryos, are essential for the formation of functional adult tissues, and are intimately involved in tissue homeostasis and wound healing.
G A, Walker   +2 more
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The myofibroblast

The American Journal of Dermatopathology, 1981
S, Lipper, L B, Kahn, R L, Reddick
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The myofibroblast and its tumours

Journal of Clinical Pathology, 2008
Tumours and tumour-like lesions of myofibroblasts may present diagnostic difficulty because of their rarity and because of uncertainties in identifying the myofibroblast. The objectives of this review are to provide a definition of the myofibroblast and an account of its biology for facilitating an understanding of the cell and of myofibroblastic ...
B, Eyden   +3 more
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Inflammatory myofibroblastic tumour

Seminars in Diagnostic Pathology, 2016
While initially controversial, the proposal that a subset of inflammatory pseudotumours were myofibroblastic neoplasms is now acknowledged. Inflammatory myofibroblastic tumour is a spindle cell neoplasm of intermediate biological potential that may arise in a wide range of anatomic sites but has a particular propensity for the lung and abdominal soft ...
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