Results 191 to 200 of about 61,389 (261)

Metabolic Reprogramming and GM‐CSF Secretion in Areca Nut‐Activated Fibroblasts Drive Oral Precancer Progression

Oral Diseases, EarlyView.
ABSTRACT Objective Oral cancer, with a rising global incidence and poor prognosis, is associated with areca nut use in South and Southeast Asia. In this study, we addressed the effects of areca nut extract (ANE) on oral carcinogenesis by modulating fibroblast behavior in oral tissue.
Yen‐Yun Wang, Chang‐Wei Su, Chih‐Huang Tseng, Pang‐Yu Chen, Hieu D. H. Nguyen, Leong‐Perng Chan, Yuk‐Kwan Chen, Shih Sheng Jiang, Steven Lo, Shyng‐Shiou F. Yuan   +9 more
wiley   +1 more source

VAP1 promotes cardiac fibrosis by enabling PDGFR signaling in myofibroblasts. [PDF]

Exp Mol Med
Huang S, Zhao Q, Shao T, Zhu C, Xue Y, Chen N, Zhang Y, Xu H, Kong M, Wang R.   +9 more
europepmc   +1 more source

Transcriptome Analysis Reveals Distinct Molecular Signatures Between Erosive and Non‐Erosive Oral Lichen Planus

Oral Diseases, EarlyView.
ABSTRACT Objectives To identify molecular mechanisms distinguishing the erosive subtype of oral lichen planus (EOLP) from the non‐erosive subtype (NEOLP) through transcriptomic analysis. Methods We analysed bulk RNA‐seq data from 30 buccal mucosa samples (13 EOLP, 17 NEOLP) using differential expression, Gene Set Enrichment Analysis (GSEA ...
Kisung Sheen, Chaerim Song, Kanghyun Kwon, Seoyeon Kim, Hye‐Ji Park, Man S. Kim   +5 more
wiley   +1 more source

Targeting cGAS-STING-macrophage axis: a novel therapeutic horizon for renal fibrosis. [PDF]

Front Immunol
Wei Q, Zhao K, Jia F, Zhou J, Liu T, Gao S.   +5 more
europepmc   +1 more source

Extracellular Matrix Remodeling in Actinic Cheilitis and Lip Squamous Cell Carcinoma: A Cross‐Sectional Study

Oral Diseases, EarlyView.
ABSTRACT Background Actinic cheilitis is a precursor to lip squamous cell carcinoma. How ultraviolet‐induced stromal degeneration relates to invasion‐related extracellular matrix markers remains unclear. This study investigated basophilic degeneration of collagen, solar elastosis, fibronectin, tenascin‐C, and podoplanin in both lesions.
Caroline Alfaia‐Silva, Polyane Caroline Arruda de Farias, Fernanda de Mello da Silva, Lidiane de Paula Ribeiro, Ericles de Paiva Vieira, Elena Riet Correa Rivero, Filipe Modolo   +6 more
wiley   +1 more source

Optimization of the in vitro Model of Cardiac Fibrosis. [PDF]

Braz J Cardiovasc Surg
Neshati Z, Esmaeili Z, Arzi F.
europepmc   +1 more source

Osteolectin/CLEC11A‐Related Signaling Molecules in Periodontitis and Peri‐Implantitis

Oral Diseases, EarlyView.
ABSTRACT Objective Periodontal and peri‐implant tissues differ histologically and biomechanically, which may be reflected in local osteogenic and mechanosensitive signaling. This exploratory cross‐sectional study aimed to compare expression profiles of Osteolectin (CLEC11A) and related signaling molecules across periodontal health, peri‐implant health,
Gözde Işıker Kara, Feyzanur Caldiran, Hatice Balci Yuce, Busenur Sahin, Ercan Cacan   +4 more
wiley   +1 more source

Fibroblast-derived neuropilin 1 alleviates renal fibrosis progression. [PDF]

J Pathol
Shen Y, Placier S, Louedec L, Frère P, Vandermeersch S, Figueroa S, François H, Chadjichristos CE, Cohen C, Chatziantoniou C, Calmont A.   +10 more
europepmc   +1 more source

Iminostilbene, a Carbamazepine Intermediate, Alleviates Myocardial Fibrosis after Myocardial Infarction via Targeting Galectin3. [PDF]

ACS Pharmacol Transl Sci
Li N, Zhou J, Wang Z, Wang M, Tian Y, Sun G.   +5 more
europepmc   +1 more source

Reviewing the benefits and clinical outcomes of oral fibroblasts over mesenchymal stem cells for repairing periodontal defects during or after orthodontic tooth movement

Periodontology 2000, EarlyView.
Abstract Orthodontic therapy applies forces to teeth, causing an inflammatory reaction in the periodontal ligament. This is repaired by remodeling of the periodontium, allowing tooth displacement. Although orthodontic therapy is mostly initiated during childhood and adolescence, the number of adults seeking this treatment is increasing as our society's
Ludovica Parisi, Eleni Mavrogonatou, Anton Sculean, Dimitris Kletsas, Martin Degen   +4 more
wiley   +1 more source